Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: Efficacy and Safety of Almonertinib Combined With Stereotactic Body Radiotherapy (SBRT) in the Treatment of Non-small Cell Lung Cancer With EGFR Sensitive Mutation: a Single-arm, Open-label Clinical Trial [NA]
This entry reports on a single-arm, open-label trial evaluating almonertinib in combination with stereotactic body radiotherapy for EGFR-mut…
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CLINICAL_TRIALS research · 2024-09-04Clinical Trial Update: Testing the Addition of Activity Monitoring With a Wearable Electronic Device to Improve Patient Care During Treatment for Lung Cancer [NA]
This clinical trial update reports that the study evaluating adding activity monitoring with a wearable device to patient care during lung c…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Pembrolizumab in Elderly Patients With Advanced Lung Cancer [Phase 2]
Phase 2 clinical trial of pembrolizumab in elderly patients with advanced non-small cell lung cancer has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Phase 2 Study of S-1 as 2nd Line Therapy in Advanced Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating S-1 as second-line therapy for advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer [NA]
A pilot study evaluating response-driven adaptive radiation therapy for locally advanced non-small cell lung cancer has completed, with resu…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Phase 2 Study of S-1 in Combination With Cisplatin as 1st Line Therapy in Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of S-1 in combination with cisplatin for first-line treatment of advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS withdrawal · 2024-09-03Clinical Trial Update: SCION: SABR and Checkpoint Inhibition of NSCLC [Phase 2]
A Phase 2 trial (SCION) evaluating stereotactic ablative radiotherapy (SABR) with checkpoint inhibition for non-small cell lung cancer has b…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Phase III trial evaluating durvalumab in combination with chemotherapy in completely resected stage II-III non-small cell lung cancer comple…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Cryoablation with or Without Serplulimab in Treating Patients with Stage I-IIA Non-small Cell Lung Cancer [NA]
A clinical trial is evaluating cryoablation with or without serplulimab for Stage I-IIA non-small cell lung cancer; the study is not yet rec…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial is evaluating stereotactic body radiotherapy for oligoprogression in metastatic non-small cell lung cancer and is c…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in NSCLC [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of combining Sintilimab with chemotherapy and cryoablation in non-small cell lung …
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC [Phase 2]
Phase 2 clinical trial evaluating high-dose radiation followed by chemotherapy and radiation for locally advanced non-small cell lung cancer…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations [Phase 2]
A Phase 2 clinical trial is evaluating the combination of lenvatinib with carboplatin, pemetrexed, and pembrolizumab for EGFR-mutant non-sma…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Active Brain Metastasis [Phase 2]
A Phase 2 clinical trial from Fudan University evaluates cranial radiotherapy combined with chemoimmunotherapy for untreated driver-mutation…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis [Phase 2]
A Phase 2 clinical trial update on cranial radiotherapy combined with chemoimmunotherapy for untreated driver-mutation negative non-small ce…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Perioperative Immunotherapy for NSCLC (ECTOP-1030) [Phase 2]
Phase 2 clinical trial update for perioperative immunotherapy in non-small cell lung cancer (ECTOP-1030), currently not yet recruiting; spon…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Incidence and Characterization of Drivers Oncogenes in the Population With Lung Cancer Afferents to the Cancer Institute in Aviano (IN.ON.D.)
This update notes an ongoing clinical trial in Italy investigating the incidence and characterization of driver oncogenes in patients with N…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing adjuvant alectinib to adjuvant platinum-based chemotherapy in ALK-positive non-small cell lung cancer; results were …
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Study Of Comparing SAF-189s With Crizotinib In First Line ALK-Positive Advanced and Metastatic NSCLC [Phase 3]
A Phase 3 trial compares SAF-189s to Crizotinib as first-line therapy for ALK-positive advanced/metastatic non-small cell lung cancer; the s…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Nintedanib for the Prevention of Radiation Pneumonia in Unresectable NSCLC
A clinical trial is evaluating nintedanib for preventing radiation pneumonitis in patients with unresectable non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Vaccine-Based Immunotherapy Regimen For NSCLC and TNBC [Phase 1]
Pfizer's Phase 1 trial of a vaccine-based immunotherapy regimen for non-small cell lung cancer and triple-negative breast cancer was termina…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer [Phase 2]
Betta Pharmaceuticals is updating a Phase 2 clinical trial evaluating Befotertinib and Icotinib in treatment-naive patients with advanced EG…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: CTS2190 Phase I /II Clinical Study in Patients [Phase 1, Phase 2]
CTS2190 is a Phase 1/2 clinical study by CytosinLab Therapeutics evaluating CTS2190 in solid tumors, including pancreatic cancer, non-small …
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Ensartinib as Adjuvant Treatment in Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating ensartinib as adjuvant therapy for ALK-positive non-small cell lung cancer is currently recruiting.
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EMA withdrawal · 2024-08-22EMA Withdrawn: Tremelimumab AstraZeneca (tremelimumab) — AstraZeneca AB
EMA has withdrawn the marketing authorization for tremelimumab for non-small cell lung cancer.