Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 study evaluating tislelizumab in combination with platinum-based chemotherapy for advanced and metastatic non-small cell lung canc…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: A Clinical Study of JMT101 in Combination With Osimertinib Versus Osimertinib Alone as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Sensitive Mutations [Phase 3]
A Phase 3 clinical trial evaluating JMT101 in combination with osimertinib versus osimertinib alone as first-line therapy for locally advanc…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: MRNA Neoantigen Vaccine in Non-Small Cell Lung Cancer [EARLY_Phase 1]
An early-phase 1 clinical trial is testing an mRNA neoantigen vaccine for non-small cell lung cancer, with recruitment not yet started.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies. [Phase 1]
A Phase I/Ib trial of NZV930 alone and in combination with PDR001 and/or NIR178 in patients with advanced malignancies has been terminated.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: A Study Developing a Non-invasive Urine-based Proteomic Model for Early Lung Cancer Detection.
A clinical trial update describing the development of a non-invasive urine-based proteomic model for early detection of lung cancer, includi…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19) [Phase 1]
Phase 1 trial update evaluating how DZD9008 influences the pharmacokinetics of cocktail probe drugs reflecting CYP3A4, P-gp, BCRP, and OATP1…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Randomized Customized Adjuvant Chemotherapy (GECP-SCAT) [Phase 3]
A Phase 3 randomized trial named GECP-SCAT evaluating customized adjuvant chemotherapy for non-small-cell lung cancer has completed. Results…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: MR-Linac Guided Adaptive FSRT for Brain Metastases From Non-small Cell Lung Cancer [Phase 2]
Completed Phase 2 trial evaluating MR-Linac guided adaptive FSRT for brain metastases in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation [Phase 1]
A Phase 1 trial evaluating the SHP2 inhibitor BBP-398 in combination with sotorasib in patients with advanced KRAS-G12C-mutant solid tumors …
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Glycoprotein in Immunotherapy Response and Efficacy Prediction of Lung Cancer
A recruiting clinical trial at Shanghai Chest Hospital is evaluating a glycoprotein as a biomarker to predict immunotherapy response and eff…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: SHP2 Inhibitor BBP-398 in Combination With Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation [Phase 1]
Phase 1 trial of the SHP2 inhibitor BBP-398 in combination with nivolumab for advanced KRAS-mutant non-small cell lung cancer has been termi…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: A Phase 2 Clinical Study of Combination Therapy With ABSK043 and Firmonertinib [Phase 2]
Phase 2 clinical study of combination therapy ABSK043 and Firmonertinib is currently recruiting for non-small cell lung cancer with EGFR mut…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: A Study in Participants With First-Line Nivolumab Plus Ipilimumb Therapy Combined With Two Cycles of Chemotherapy for Metastatic Non-Small Cell Lung Cancer
This clinical trial update describes a first-line study in metastatic non-small cell lung cancer evaluating nivolumab plus ipilimumab with t…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Tumor-specific T Cells in Lung Cancer [NA]
A clinical trial update indicates a study evaluating tumor-specific T cells for non-small cell lung cancer is currently active but not recru…
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CLINICAL_TRIALS withdrawal · 2024-12-12Clinical Trial Update: Pre-Operative Immuno-Modulatory SBRT (POIMS Trial): A Pilot Trial in Early Stage NSCLC [NA]
The POIMS trial investigating pre-operative immuno-modulatory SBRT in early-stage non-small cell lung cancer has been withdrawn. The study i…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study [Phase 2]
Phase II single-arm study evaluating furmonertinib plus bevacizumab as first-line therapy for EGFR-mutant non-small cell lung cancer with br…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Efficacy and Safety of Vorolanib Monotherapy As Third-line or Later Treatment for Advanced Non-small Cell Lung Cancer Patients: a Single-arm, Prospective, Open-label Phase II Clinical Study [Phase 2]
A Phase II single-arm study evaluating vorolanib as third-line or later monotherapy for advanced non-small cell lung cancer; the trial is cu…
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CLINICAL_TRIALS withdrawal · 2024-12-10Clinical Trial Update: Aumolertinib in EGFR-Mutant Resected Stage IB-IIIA NSCLC (AERESA). [Phase 2]
A phase 2 trial of Aumolertinib for EGFR-mutant resected non-small cell lung cancer (AERESA) was withdrawn, with no results reported.
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CLINICAL_TRIALS withdrawal · 2024-12-10Clinical Trial Update: NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations. [Phase 2]
The Phase 2 neoadjuvant gefitinib trial for unresectable stage III non-small cell lung cancer with EGFR mutations has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-12-10Clinical Trial Update: APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLC [Phase 2]
Phase 2 trial of Apatinib plus chemotherapy versus chemotherapy for first-line treatment of advanced non-small cell lung cancer has been wit…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Cognitive Screening in Lung Cancer Patients
A clinical trial investigating cognitive screening in lung cancer patients is currently recruiting, including non-small cell and small cell …
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: ONO-4538 Study in Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study of ONO-4538 (nivolumab) in patients with advanced non-small cell lung cancer has completed. Results were posted on 2024-12-09.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment
This completed clinical trial update examines how prevalent brain metastases are in lung cancer and assesses their impact on survival across…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating immunotherapy combinations in patients with non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors [Phase 2]
This clinical trials update describes a multicenter, open-label Phase IIa study to evaluate the efficacy and safety of B1962 injections in a…