Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Study of IBI363 in Subjects with Advanced Solid Malignancies [Phase 2]
Phase 2 study of IBI363 in advanced solid malignancies is currently recruiting, with indications including melanoma, non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Integrating Machine Learning for Prognostic Prediction in Stage I NSCLC by CT Images and Pathological Factors
A completed clinical trial reports on integrating machine learning with CT imaging and pathological factors to prognosticate stage I non-sma…
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FDA approval · 2024-12-18FDA Approved: ENSACOVE — Original Application (Xcovery Holdings, Inc.)
FDA approved ENSARTINIB (ENSACOVE) from Xcovery Holdings in an original application for adults with ALK-positive metastatic non-small cell l…
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FDA approval · 2024-12-18FDA Approved: RETEVMO — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for RETEVMO (selpercatinib) by Eli Lilly, expanding its approved indications for RET fusion-positive…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluated the combination of eftilagimod alpha (IMP321) with pembrolizumab in patients with previously untreated unresectabl…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer [Phase 3]
An ongoing Phase 3 clinical trial comparing photon therapy to proton therapy for non-small cell lung cancer. The study is currently ACTIVE_N…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: A Randomized, Placebo Controlled Study to Evaluate the Safety and Potential Efficacy of MS-20 in Combination with Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer [NA]
This completed randomized, placebo-controlled study evaluated the safety and potential efficacy of MS-20 in combination with pembrolizumab f…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors [Phase 1]
This Phase 1 clinical trial update evaluates CAR-macrophages targeting HER2-overexpressing solid tumors, sponsored by Carisma Therapeutics. …
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Pulsed Electric Field Ablation Devices in the Treatment of Lung Tumors [NA]
A clinical trial update describes evaluating the efficacy and safety of pulsed electric field ablation devices for treating lung tumors, inc…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: PRedictive Value of Multiparametric Dynamic WB 18F-FDG-PET Imaging on a LAFOV System for FIRST-line Chemo-immunotherapy Efficacy in Advanced Non-small-cell Lung Cancer: PROFIL-1
This clinical trial investigates the predictive value of multiparametric dynamic whole-body 18F-FDG-PET imaging on a long-axial FOV system f…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial [NA]
This clinical trial evaluates the diagnostic value of bronchoscopic needle-based confocal laser endomicroscopy (nCLE) as a real-time tool to…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Cross-sectorial Rehabilitation of Patients with Lung Cancer [NA]
An ongoing clinical trial examining cross-sector rehabilitation for patients with non-small cell lung cancer, currently recruiting.
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EMA approval · 2024-12-17EMA Authorised: Vizimpro (dacomitinib monohydrate) — Pfizer Europe MA EEIG
The European Medicines Agency authorised Vizimpro (dacomitinib monohydrate) for non-small cell lung cancer, with Pfizer Europe MA EEIG as th…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Multicenter Analysis of Different Approaches in Segmentectomies in Early-stage Lung Cancer
A multicenter trial is recruiting to compare different segmentectomy approaches for early-stage lung cancer, including non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Dose Individualization of Pemetrexed - IMPROVE-I [Phase 4]
This report provides an update on the Phase 4 IMPROVE-I trial evaluating dose individualization of pemetrexed in non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A Study Comparing SB8 and Avastin® in Patients With Advanced Non-squamous Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing the bevacizumab biosimilar SB-8 to Avastin in adults with advanced non-squamous non-small cell lung cancer; results …
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 dose-escalation study of JAB-3068, an SHP2 inhibitor, in adults with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Clinical Outcomes of Patients With Resectable Non-Small Cell Lung Cancer Receiving Neoadjuvant Nivolumab Plus Chemotherapy in France
A completed clinical trial reports outcomes for patients with resectable non-small cell lung cancer who received neoadjuvant nivolumab in co…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: A Multicenter Real-world Clinical Study on the Efficacy and Safety of Ensartinib As Neoadjuvant Treatment for Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer (NSCLC) Patients.
The document describes a multicenter real-world study evaluating ensartinib as neoadjuvant therapy for ALK-positive non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A Phase I/IIa Study of UV1 Vaccination in Patients With Non Small Cell Lung Cancer. [Phase 1, Phase 2]
A Phase 1/2a clinical trial evaluating UV1 vaccination in non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Neoadjuvant Envafolimab Plus Disitamab Vedotin and Carboplatin in Resectable HER2-Mutant Non-Small-Cell Lung Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating Envafolimab in combination with Disitamab Vedotin and Carboplatin for resectable HER2-mutant non-s…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Adebrelimab Plus Chemo and Recaticimab in Perioperative Treatment of Resectable NSCLC [Phase 2]
Phase 2 clinical trial evaluating adebrelimab plus chemotherapy and recaticimab as perioperative treatment for resectable non-small cell lun…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Liquid Biopsy for Early Non-small Lung Cancer Detection
A completed clinical trial evaluating a liquid biopsy approach for early detection of non-small cell lung cancer.
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study
MEKANOS is a clinical trial evaluating tumoral bone strength using numerical simulation with quantitative CT in patients with bone metastase…