Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-loaded DC Vaccine, PD-1 Inhibitor, and Radiotherapy for Advanced NSCLC Progressed After Second-line Treatment [Phase 2]
Phase 2 trial evaluating a neoantigen-loaded dendritic cell vaccine in combination with a PD-1 inhibitor and radiotherapy for advanced non-s…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: A Study of TY-9591 With Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor NSCLC [Phase 2]
Phase 2 clinical trial update evaluating TY-9591 in combination with chemotherapy as first-line treatment for EGFR-mutated non-small cell lu…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-loaded DC Vaccine, PD-1 Inhibitor, and Radiotherapy for Advanced NSCLC Progressed After First-line Treatment [NA]
This clinical trial investigates a combination therapy for advanced non-small cell lung cancer involving a neoantigen-loaded dendritic cell …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Aumolertinib Versus Osimertinib As First-line Therapy for Patients with EGFR Mutated Locally Advanced or Metastatic Non-small-cell Lung Cancer [Phase 2]
Phase 2 trial comparing Aumolertinib to Osimertinib as first-line therapy for EGFR-mutated locally advanced or metastatic non-small cell lun…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy. [Phase 3]
A Phase 3 trial evaluating AL2846 capsule in combination with TQB2450 injection versus docetaxel in advanced non-small cell lung cancer pati…
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CLINICAL_TRIALS other · 2024-12-30Clinical Trial Update: Expanded Access Program (EAP) Designed to Provide Access to Botensilimab and Balstilimab Before Regulatory Approval
Agenus has launched an Expanded Access Program to provide Botensilimab and Balstilimab to patients before regulatory approval. The program t…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-based Peptide Vaccine, PD-1 Inhibitor, and Radiotherapy for Advanced NSCLC Progressed After First-line Treatment [NA]
A study evaluating a combination of a neoantigen-based peptide vaccine, a PD-1 inhibitor, and radiotherapy for advanced non-small cell lung …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Neoantigen-based Peptide Vaccine, PD-1 Inhibitor, and Radiotherapy for Advanced NSCLC Progressed After Second-line Treatment [Phase 2]
Phase 2 clinical trial evaluating a neoantigen-based peptide vaccine in combination with a PD-1 inhibitor and radiotherapy for advanced non-…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study evaluating CM24 in combination with nivolumab in adults with advanced…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma
This non-interventional real-world study assesses afatinib as first-line therapy and subsequent treatments in patients with advanced EGFR mu…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Disitamab Vedotin in Combination with Tislelizumab and Bevacizumab in a Phase II Clinical Study of Locally Advanced or Metastatic Non-small Cell Lung Cancer with HER2 Mutation/amplification/expression [Phase 2]
Clinical trial update announcing a Phase II study of Disitamab Vedotin in combination with Tislelizumab and Bevacizumab for locally advanced…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting [Phase 2]
This is a Phase 2 exploratory study evaluating tislelizumab in combination with chemotherapy for immuno-experienced patients with EGFR/ALK/R…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Impact of Concomitant Use of Steroids and Immune-Checkpoint Inhibitors on Survival Outcomes in NSCLC Patients
This clinical trial update discusses how the concurrent use of steroids with immune-checkpoint inhibitors may influence survival outcomes in…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: A Phase II Clinical Study to Evaluate the Safety, Pharmacokinetic Profile, and Preliminary Efficacy of IMM2510 in Combination with Chemotherapy As First-line Treatment in Subjects with Non-small Cell Lung Cancer or Triple-negative Breast Cancer [Phase 2]
Phase II clinical study to evaluate safety, pharmacokinetics, and preliminary efficacy of IMM2510 in combination with chemotherapy as first-…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Real-World Immuno-Radiotherapy for Advanced NSCLC
A real-world trial update on immuno-radiotherapy for advanced non-small cell lung cancer, with the study status reported as completed.
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Oral AMXT 1501 Dicaprate in Combination With IV DFMO [Phase 1, Phase 2]
A Phase 1/2 trial of oral AMXT 1501 dicaprate in combination with IV DFMO has been terminated.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer [Phase 1, Phase 2]
Phase 1/2 study assessing safety, tolerability, and preliminary efficacy of CJRB-101 in combination with pembrolizumab in selected advanced …
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating durvalumab after chemoradiation and as consolidation therapy for stage III non-small cell lung cancer was termina…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India [Phase 4]
Phase 4 clinical trial update evaluating lorlatinib in ALK inhibitor-treated unresectable advanced or recurrent ALK-positive non-small cell …
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Neoadjuvant/Adjuvant Cadonilimab Plus Chemotherapy in Patients With Resectable PD-L1 Negative NSCLC [Phase 2]
A Phase 2 clinical trial is investigating neoadjuvant/adjuvant cadonilimab plus chemotherapy in patients with resectable PD-L1 negative non-…
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CLINICAL_TRIALS withdrawal · 2024-12-20Clinical Trial Update: Durvalumab (MEDI4736) and Radiosurgery (fSRT Vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases [Phase 2]
A Phase 2 trial evaluating durvalumab with radiosurgery for brain metastases from non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: FMT+Immunotherapy+Chemotherapy As First-line Treatment for Driver-gene Negative Advanced NSCLC [Phase 2]
A Phase 2 clinical trial evaluating fecal microbiota transplantation combined with immunotherapy and chemotherapy as first-line treatment fo…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Surgery After Verifying Existing Disease in Locally Advanced Operable Lung Cancer: A Pilot Study [Phase 1]
A Phase 1 pilot trial assesses performing surgery after confirming existing disease in locally advanced operable non-small cell lung cancer.…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Phase I/II Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer [NA]
A Phase I/II neoadjuvant study evaluating cemiplimab in combination with dupilumab in patients with early-stage non-small cell lung cancer; …
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Individualized Lung Tumor Stereotactic Ablative Radiotherapy (iSABR) [NA]
The individualized lung tumor stereotactic ablative radiotherapy (iSABR) trial for non-small cell lung cancer has completed and posted resul…