Neurofibromatosis Type
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial [NA]
This clinical trial update describes an internal pilot feasibility study and follow-up randomized controlled trial of Acceptance and Commitm…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1 [Phase 1]
Phase 1 study evaluating the feasibility and tolerability of talimogene laherparepvec (IMLYGIC) for treating cutaneous neurofibromas in adul…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: FARD (RaDiCo Cohort) (RaDiCo-FARD)
The RaDiCo-FARD clinical trial sponsored by INSERM is currently recruiting, studying a cohort of patients with inherited skin and ectodermal…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs
An update on an observational study evaluating the effect and safety of selumetinib in pediatric patients with NF1-associated plexiform neur…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas [Phase 2]
A Phase 2 clinical trial evaluating a combination of selumetinib, a bromodomain inhibitor, and durvalumab for sarcomas, with recruitment not…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST] [EARLY_Phase 1]
Early-phase window-of-opportunity trial evaluating the combination of mirdametinib and vorinostat for NF1-associated, H3K27 trimethylation-d…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN) [Phase 1]
A Phase 1 study of selumetinib in Chinese pediatric and adult subjects with Neurofibromatosis Type 1 and inoperable plexiform neurofibromas …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: NF-1, Nutraceutical Intervention [Phase 1]
This Phase 1 clinical trial update investigates a nutraceutical intervention for Neurofibromatosis type 1, sponsored by the Masonic Cancer C…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1
This Johns Hopkins University study is developing multi-parameter biomarkers to predict malignant transformation in Neurofibromatosis type 1…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) [Phase 2]
This update covers an ongoing Phase 2 clinical trial (INTUITT-NF2) evaluating targeted therapies for NF2-related schwannomatosis. The study …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Neurofibromatosis Type 1 Tumor Early Detection Study
This clinical trial update announces a study for early detection of tumors in Neurofibromatosis Type 1, and the study is currently recruitin…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Resiliency Training in Adolescents With NF1 and NF2 [NA]
Clinical trial update describing resiliency training for adolescents with neurofibromatosis types 1 and 2; the study is currently active but…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: RASopathy Biorepository
This clinical trial update indicates that the RASopathy Biorepository is currently recruiting participants with various RASopathy-related co…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study of Aspirin in Patients With Vestibular Schwannoma [Phase 2]
Phase 2 clinical trial update for aspirin in vestibular schwannoma patients; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Doxycycline in Cutaneous Schwannoma (NF2) [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating doxycycline for cutaneous schwannomas in Neurofibromatosis Type 2, sponsored by Massachusetts Eye a…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas [Phase 1]
Phase 1 clinical trial evaluating PAS-004 in adults with Neurofibromatosis Type 1 and related plexiform neurofibromas; currently recruiting.
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Natural History Study of Cutaneous Neurofibromas in People With NF1
Observational natural history study of cutaneous neurofibromas in people with Neurofibromatosis Type 1; the study is active but not currentl…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1 [NA]
A decentralized clinical trial at Massachusetts General Hospital is investigating evidence-based care for underserved patients with Neurofib…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)
This ClinicalTrials.gov entry describes a National Cancer Institute-sponsored study to surveil malignant transformation of NF1-related perip…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Function of the Pigment Epithelium in Patients With Type 1 Neurofibromatosis
A completed clinical trial evaluating the function of the pigment epithelium in patients with Neurofibromatosis Type 1.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1 Using Novel Magnetic Resonance Imaging Techniques Paired With Artificial Intelligence [NA]
This clinical trial is recruiting pediatric patients with Neurofibromatosis Type 1 to identify pre-malignant lesions using novel MRI techniq…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1
This ongoing clinical trial aims to develop biomarkers to measure plexiform tumor burden in patients with neurofibromatosis type 1.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Phase II Study of FCN-159 in NF2 Nerve Sheath Tumors [Phase 2]
Phase II clinical trial of FCN-159 for NF2-related nerve sheath tumors is currently recruiting at the Cancer Institute and Hospital, Chinese…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST [Phase 1, Phase 2]
An early-phase clinical trial is evaluating the combination of a MEK inhibitor and an MDM2 inhibitor in patients with Neurofibromatosis type…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Interventions for Reading Disabilities in NF1 [Phase 2]
Phase 2 clinical trial evaluating interventions for reading disabilities in Neurofibromatosis Type 1 is currently active but not recruiting.