Neurofibromatosis Type
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 [Phase 2]
Phase 2 trial assessing N-acetylcysteine as antioxidant therapy in children with Neurofibromatosis Type 1 has completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 [Phase 1]
A Phase 1 trial investigating the transformation of plexiform neurofibromas into malignant peripheral nerve sheath tumors in Neurofibromatos…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
This is an update on a completed observational clinical trial studying the natural history and biology of skin neurofibromas in Neurofibroma…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1 [Phase 2]
Phase 2 open-label trial evaluating safety and effects of HLX-1502 in patients with Neurofibromatosis Type 1 is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas [Phase 2]
Phase 2 clinical trial of crizotinib in children and adults with Neurofibromatosis type 2 and progressive vestibular schwannomas has complet…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas [Phase 1]
A Phase 1 clinical trial is evaluating the combination of cabozantinib and selumetinib for plexiform neurofibromas in Neurofibromatosis type…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs) [NA]
A clinical trial evaluating repeat monthly Alexandrite laser treatment for neurofibromatosis type 1-associated cutaneous neurofibromas is cu…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas [Phase 2]
Phase 2 trial update for the MEK inhibitor selumetinib in adults with Neurofibromatosis Type 1 and inoperable plexiform neurofibromas; the s…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) [Phase 2]
Phase 2 trial of NFX-179 topical gel for adults with Neurofibromatosis Type 1 and cutaneous neurofibromas has completed, and results have be…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Precision Medicine for Neurocutaneous Syndromes in Western China
A completed clinical trial from West China Hospital exploring precision medicine approaches for neurocutaneous syndromes, including NF1, TSC…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing [NA]
A completed study evaluating resiliency training delivered to adults with neurofibromatosis via live videoconferencing.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1
A Stanford University–led clinical trial evaluating genetic modifiers of cutaneous neurofibromas in adults with Neurofibromatosis type 1 has…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas [Phase 1]
Phase 1 trial evaluating whether cooling the skin reduces pain during non-invasive treatments for neurofibromatosis type 1 cutaneous neurofi…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas [Phase 3]
Phase 3 clinical trial results evaluate the efficacy and safety of selumetinib in adults with neurofibromatosis type 1 and symptomatic, inop…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating REC-2282 in progressive NF2-mutated meningiomas has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas [Phase 2]
Phase 2 clinical trial of the MEK inhibitor mirdametinib for Neurofibromatosis type 1–associated plexiform neurofibromas has posted results.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.
A completed clinical trial update exploring the mechanisms behind cutaneous neurofibroma formation in neurofibromatosis type 1 using a trans…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN [Phase 1, Phase 2]
Phase 1/2 trial evaluating pharmacokinetics, safety, and efficacy of a granule formulation of selumetinib in children with Neurofibromatosis…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II [Phase 2]
Phase II clinical trial evaluating photodynamic therapy for benign dermal neurofibromas in Neurofibromatosis Type 1. The study is currently …
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1
The clinical trial evaluating mitochondrial dysfunction in Neurofibromatosis type 1 has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas [Phase 2]
Phase II trial of binimetinib in children and adults with NF1-associated plexiform neurofibromas has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial [NA]
The document reports the completion and posting of results from a clinical trial evaluating the iCanCope mobile app for chronic pain in adul…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Phase II Trial of Poly-ICLC for Low-Grade Gliomas [Phase 2]
A terminated Phase II trial evaluating poly-ICLC for low-grade gliomas in NF1 patients has posted results.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1 [NA]
This clinical trial update reports completion of a study evaluating clinical hypnosis and home blood pressure monitoring for managing hypert…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas [Phase 1]
Phase 1 trial evaluating dosing and tolerability of deoxycholic acid versus polidocanol for treating cutaneous neurofibromas in neurofibroma…