Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Fecal Microbiota Transplant for Neuroblastoma in a Single Patient
A clinical trial update reports fecal microbiota transplant for neuroblastoma in a single patient, and the study is no longer available.
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial [Phase 1]
Phase 1 GD2-targeted CAR-T cell therapy (GD2CART) for recurrent/refractory neuroblastoma and osteosarcoma has a suspended status as of the u…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Phase I Study of 131-I mIBG Followed by Nivolumab & Dinutuximab Beta Antibodies in Children With Relapsed/Refractory Neuroblastoma [Phase 1]
Phase I study of 131-I mIBG followed by nivolumab and dinutuximab beta for children with relapsed/refractory neuroblastoma is listed as acti…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors [Phase 1]
A Phase 1 trial evaluating ribociclib in combination with topotecan and temozolomide (TOTEM) in pediatric patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastoma [Phase 2]
Phase 2 trial evaluating Hu3F8/GM-CSF immunotherapy plus isotretinoin in patients in first remission of high-risk neuroblastoma has complete…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Local Control With Reduced-dose Radiotherapy for High-Risk Neuroblastoma [EARLY_Phase 1]
This EARLY Phase 1 trial evaluated reduced-dose radiotherapy for high-risk neuroblastoma and has completed.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: 67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma [Phase 1, Phase 2]
A pediatric Phase 1/2 trial of the radiopharmaceutical 67Cu-SARTATE for high-risk, relapsed, or refractory neuroblastoma has been terminated…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922) [Phase 1]
This update reports the completion of a Phase 1 study of lorlatinib (PF-06463922) in neuroblastoma. Results from the trial have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Evaluation of 2 Intensification Treatment Strategies for Neuroblastoma Patients With a Poor Response to Induction [Phase 2]
This update reports a Phase 2 trial evaluating two intensified treatment strategies for patients with very high-risk neuroblastoma who had a…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma [Phase 1, Phase 2]
Phase 1/2 study evaluating abemaciclib in combination with other anti-cancer therapies in children and young adults with solid tumors, inclu…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastoma [Phase 1, Phase 2]
Clinical trial update for high-risk neuroblastoma evaluating allogeneic tumor cell vaccination with oral metronomic cyclophosphamide (Phase …
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma [Phase 1]
Phase 1 study evaluating the combination of Hu3F8, a humanized anti-GD2 antibody, with allogeneic natural killer cells for high-risk neurobl…
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CLINICAL_TRIALS trial_result · 2025-07-21Clinical Trial Update: Clinical Application Study of [123I]Metaiodobenzylguanidine and Somatostatin Receptor-Targeted Imaging in the Diagnosis and Staging of Neuroblastoma
This clinical trial update describes an imaging-based diagnostic study using [123I]Metaiodobenzylguanidine and somatostatin receptor-targete…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: 9-ING-41 in Pediatric Patients With Refractory Malignancies. [Phase 1]
Phase 1 trial of 9-ING-41 in pediatric patients with refractory malignancies was terminated; the update does not include study results.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Biomarkers of Renal Dysfunction in Neuroblastoma Survivors
A completed clinical trial from Memorial Sloan Kettering Cancer Center examining biomarkers of renal dysfunction in survivors of neuroblasto…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma [Phase 1]
Phase 1 feasibility trial evaluating prolonged naxitamab, irinotecan, and temozolomide in relapsed or refractory neuroblastoma; the study is…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells [Phase 1, Phase 2]
Phase I/II trial evaluating immunization with lymphotactin and interleukin-2 gene-modified neuroblastoma tumor cells; study has completed.
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant after chemotherapy for recurrent or refractory high-risk solid tumors in pediatric and…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Phase II Study of Combined Chemotherapy With Arsenic Trioxide in Stage 4/M Neuroblastoma [Phase 2]
Phase II clinical trial evaluating arsenic trioxide in combination with chemotherapy for stage 4/M neuroblastoma; results posted on 2025-05-…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: MIBG With Dinutuximab +/- Vorinostat [Phase 1]
Phase 1 trial evaluating MIBG with dinutuximab, with or without vorinostat, in neuroblastoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: GVAX Plus Checkpoint Blockade in Neuroblastoma [Phase 1]
The Phase 1 trial of GVAX plus checkpoint blockade in neuroblastoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…