Myeloproliferative Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: WELL-MPN: A Digital Lifestyle App for Patients With MPNs [NA]
This entry notes a not-yet-recruiting clinical trial assessing a digital lifestyle app (WELL-MPN) for patients with myeloproliferative neopl…
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EMA approval · 2026-01-13EMA Authorised: Inrebic (fedratinib dihydrochloride monohydrate) — Bristol Myers Squibb Pharma EEIG
The European Medicines Agency authorised Inrebic for myeloproliferative neoplasms, including primary myelofibrosis, with Bristol Myers Squib…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE) [NA]
This clinical trial evaluates whether NETosis biomarkers can predict thrombosis risk in patients with myeloproliferative neoplasms and is cu…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT [Phase 1]
Phase 1 trial evaluating a combination of CD25/Treg-depleted donor lymphocyte infusion with ipilimumab for relapse of myeloid diseases after…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating GVHD prophylaxis with post-transplant cyclophosphamide plus sirolimus and VIC-1911 in myeloablative peripheral bl…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms [Phase 2]
Phase 2 study evaluating luspatercept for anemia in patients with lower-risk myelodysplastic syndromes or non-proliferative myeloproliferati…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Aprepitant Versus Hydroxyzine in Persistent Aquagenic Pruritus for Patients With Myeloproliferative Neoplasms [Phase 3]
A Phase 3 randomized trial comparing aprepitant to hydroxyzine in persistent aquagenic pruritus for patients with myeloproliferative neoplas…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched Donor [Phase 2]
Phase 2 clinical trial update evaluating post-transplantation benadamustine and cyclophosphamide in high-risk myeloid malignancies with part…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation [Phase 1]
A Phase 1 clinical trial is evaluating the combination of ivosidenib and ruxolitinib in adults with advanced myeloproliferative neoplasms ha…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Investigation of the Genetics of Hematologic Diseases
A St. Jude-sponsored clinical trial update indicates a study on the genetics of hematologic diseases is currently recruiting, covering sever…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
This ClinicalTrials.gov update describes an ongoing study that collects tissue, blood, and body fluid samples from patients with hematologic…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CPI-0610 with and without ruxolitinib in patients with hematologic and myeloproliferative malignancies. …
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial from University of Alabama at Birmingham evaluating a two-step anti-thymocyte globulin regimen to prevent acute gra…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating a two-step anti-thymocyte globulin (ATG) regimen to prevent acute graft-versus-host disease after myeloablative all…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)
Clinical Trial Update for the MPN-IFN study shows that it remains active but not recruiting, studying autoantibodies against Type I Interfer…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Unveiling the Germline Predisposition to Myeloproliferative Neoplasms
A clinical trial update from Fondazione IRCCS Policlinico San Matteo di Pavia on germline predisposition to myeloproliferative neoplasms, cu…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients [NA]
A pilot lifestyle intervention trial is recruiting patients with myeloproliferative neoplasms and leukemia at Massachusetts General Hospital…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY).
Clinical trial PROPHECY investigates patient-reported outcomes in Philadelphia-negative cytogenetic myeloproliferative neoplasms. The study …
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Myeloproliferative Neoplasms (MPN) and COVID-19
Clinical trial update indicating completion of a study on myeloproliferative neoplasms and COVID-19. Sponsor: Fondazione per la Ricerca Ospe…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Establishment of a Strategy for Preventing Graft-versus-host Disease After Allogeneic Hematopoietic Cell Transplantation by Exploring Immune Mechanisms of Regulatory and Effector T Cells
This clinical trial update outlines an approach to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation by …
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk [Phase 3]
A Phase 3 clinical trial evaluating P1101 in patients with early or overt primary myelofibrosis at low or intermediate-1 risk is currently r…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Hematological Disorders in EHPVO Patients
A clinical trial update describes a study on hematological disorders in patients with Extrahepatic portal vein obstruction and thrombophilia…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Role of Monocytes Sub-populations in Thrombosis Associated With Myeloproliferative Neoplasms (MonSThr)
Update on a completed clinical trial investigating how monocyte sub-populations contribute to thrombosis in myeloproliferative neoplasms (Mo…