Myeloproliferative Neoplasms
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase 2 Study Of Imetelstat for Patient With Myelodysplastic/Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial update for imetelstat in patients with myelodysplastic/myeloproliferative neoplasms; the study status is NOT_YET_RECR…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms [Phase 1, Phase 2]
The Phase 1/2 study evaluating the combination of ruxolitinib and CPX-351 in advanced phase myeloproliferative neoplasms was terminated, wit…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015 [NA]
This clinical trial update reports on predictive clinical and biological parameters across acute leukemia, myelodysplastic syndromes, and my…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL) [Phase 2]
Phase 2 study of fedratinib in myeloproliferative neoplasms, chronic neutrophilic leukemia, and myelodysplastic syndromes; the trial is not …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms [Phase 1]
This clinical trial update describes a Phase 1 study evaluating INCA033989 as a monotherapy or in combination with ruxolitinib in participan…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm [Phase 2]
This clinical trial update reports a Phase 2 study evaluating olutasidenib in combination with hypomethylating agents for IDH1-mutated highe…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Study of INCA036978 in Participants With Myeloproliferative Neoplasms [Phase 1]
This clinical trial update reports a Phase 1 study of INCA036978 in participants with myeloproliferative neoplasms, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms [Phase 1]
This clinical trial update announces a Phase 1 study of JNJ-88549968 for CALR-mutated myeloproliferative neoplasms and indicates the trial i…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia [NA]
The ENERGIA study tests a personalized exercise program to reduce fatigue in patients with myeloproliferative neoplasms and chronic myeloid …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft [Phase 1]
A Stanford-sponsored Phase 1 trial is evaluating reduced-intensity, allogeneic hematopoietic cell transplantation with a T-cell–depleted gra…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms [Phase 1]
A Phase 1 clinical trial is evaluating the safety and tolerability of INCB160058 in participants with Myeloproliferative Neoplasms and is cu…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms [Phase 1]
This clinical trial update describes a Phase 1 study evaluating INCA035784 in participants with myeloproliferative neoplasms, currently recr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation [Phase 1]
Phase 1 trial evaluating CIML NK cell infusion for relapse of myeloid disease after hematopoietic cell transplantation; the study is current…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms [Phase 1]
An update on a Phase 1 safety and tolerability study of INCB057643 in myelofibrosis and other advanced myeloid neoplasms, with the trial cur…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of PRT12396 in select myeloproliferative neoplasms is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms [Phase 1]
This entry describes a Phase 1 clinical trial evaluating INCA033989 as a monotherapy or in combination with ruxolitinib in participants with…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clonal Hematopoiesis of Immunological Significance
This is a clinical trial update about clonal hematopoiesis of immunological significance (CHIS) sponsored by Assistance Publique - Hôpitaux …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Pacritinib With Aza for Upfront Myelodysplastic Syndrome [Phase 1, Phase 2]
An ongoing Phase 1/2 trial is evaluating pacritinib in combination with azacitidine for upfront treatment of myelodysplastic syndromes; the …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders [Phase 2]
Phase 2 clinical trial evaluating cord blood transplant in children and young adults with blood cancers and select non-malignant disorders; …
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating CMV-MVA Triplex vaccination in HLA-matched related stem cell donors to prevent cytomegalovirus infection i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms [Phase 1, Phase 2]
This clinical trial aims to identify the optimal dose of N-acetylcysteine in patients with myeloproliferative neoplasms. It spans Phase 1/2 …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Feasibility of a Multi-omics Platform for Hematological Malignancies [NA]
This clinical trial update assesses the feasibility of a multi-omics platform for hematological malignancies and is currently recruiting. It…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders [Phase 2]
Phase 2 clinical trial update evaluating a geriatric assessment to guide treatment planning for older adults with myelodysplastic syndromes,…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Exercise Training in Patients With Myeloproliferative Neoplasms [NA]
This entry updates a clinical trial registry for an exercise training study in patients with myeloproliferative neoplasms that is not yet re…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)
This entry describes the MPN PROGRESSion Registry, an observational study to track symptoms, treatments, and disease progression in people w…