Medulloblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma [Phase 1]
Phase 1 clinical trial evaluating IL13Ralpha2-CAR T cells for treating leptomeningeal metastasis, glioblastoma, ependymoma, and medulloblast…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma [Phase 2]
Phase 2 clinical trial evaluating DFMO as maintenance therapy for molecular high/very high risk and relapsed medulloblastoma is currently re…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Digoxin Medulloblastoma Study [Phase 2]
Phase 2 clinical trial evaluating digoxin for medulloblastoma is currently recruiting at H. Lee Moffitt Cancer Center; the study targets Med…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation [EARLY_Phase 1]
This is a pediatric early-phase 1 trial update evaluating intrathecal topotecan with maintenance chemotherapy for high-risk embryonal centra…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate sodium thiosulfate for reducing hearing loss in children with medulloblastoma.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors [Phase 2]
A Phase 2 clinical trial update describes an antiangiogenic therapy for children with recurrent medulloblastoma, ependymoma, ATRT, and other…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: An Intermediate Expanded Use Trial of DFMO
This is an update on an intermediate expanded-use trial of DFMO for neuroblastoma and several embryonal CNS tumors, including medulloblastom…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma [Phase 2]
A Phase 2 clinical trial investigating reduced craniospinal radiation therapy and chemotherapy for younger patients with newly diagnosed WNT…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma [Phase 2]
This is a Phase 2 clinical trial update from St. Jude investigating molecular and clinical risk-directed therapy for newly diagnosed medullo…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors [Phase 4]
Phase 4 HeadStart4 trial for newly diagnosed children under 10 with medulloblastoma and other CNS embryonal tumors. The study status is ACTI…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma [Phase 2]
An update on an ongoing Phase 2 clinical trial evaluating 131I-Omburtamab for recurrent Medulloblastoma and recurrent Ependymoma. The trial …
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Components of Social Functioning in Survivors of Pediatric Brain Tumors
This clinical trial update reports on social functioning components in survivors of pediatric brain tumors, including medulloblastoma, and n…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: B7-H3.CD28Z.CART in CNS Neoplasms [Phase 1]
A Phase 1 clinical trial evaluating B7-H3.CD28Z.CART for central nervous system neoplasms is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults [Phase 1]
Stanford is conducting a Phase 1 study of GPC2-CAR T cell therapy for relapsed or refractory medulloblastoma and related CNS embryonal tumor…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour [Phase 3]
A Phase 3 clinical trial is investigating whether metformin improves behavior and brain function in children treated for medulloblastoma, an…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors [Phase 1]
Clinical trial update indicating that Loc3CAR (B7-H3-CAR T cells) delivery is in early-phase pediatric CNS tumor trials and currently recrui…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study of liothyronine in combination with the BIT regimen for medulloblastoma, with or without …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer [Phase 1]
A Phase 1 trial evaluating the safety of a chemo-immunotherapy combo of ibrutinib and indoximod in pediatric brain tumor patients, including…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG [Phase 2]
Phase 2 pediatric trial evaluating indoximod with chemotherapy and radiation for relapsed brain tumors or newly diagnosed diffuse intrinsic …
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CLINICAL_TRIALS withdrawal · 2026-01-08Clinical Trial Update: Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies [Phase 1]
A Phase 1 trial investigating fourth-ventricular administration of nivolumab with methotrexate or 5-azacytidine for recurrent medulloblastom…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma [Phase 3]
A Phase 3 clinical trial compares two standard regimens for treating low-risk medulloblastoma, focusing on neurocognitive outcomes. The stud…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms [Phase 1]
Phase I trial update indicates ONC206 is being studied for recurrent and rare primary central nervous system neoplasms and the study is curr…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional HER2-targeted CAR T-cell therapy for pediatric recurrent or refractory central nervous system tumors a…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Medulloblastoma Online Video-based Exercise Pilot Study [NA]
The document reports a recruiting pilot study evaluating an online video-based exercise program for children with medulloblastoma.