Clinical Trial Update: Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors [Phase 1]

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Summary

Clinical trial update indicating that Loc3CAR (B7-H3-CAR T cells) delivery is in early-phase pediatric CNS tumor trials and currently recruiting.

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Diseases / indications

• Atypical Teratoid Rhabdoid Tumor
• Central Nervous System Neoplasms
• Diffuse Midline Glioma H3 K27m-mutant
• Ependymoma
• Glioblastoma
• High-grade Glioma
• Medulloblastoma

Drugs mentioned

• Loc3CAR (B7-H3-CAR T cells)

Snippet

Sponsor: St. Jude Children's Research Hospital | Conditions: Central Nervous System Neoplasms, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Status: RECRUITING