Malignant Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of Avutometinib and Defactinib in malignant brain tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma [NA]
A clinical trial is currently recruiting to assess the efficacy of a mixed distancial neuropsychological rehabilitation program in patients …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: 18F-Fluciclovine PET-MRI in High-grade Glioma [EARLY_Phase 1]
An early-phase trial evaluating 18F-Fluciclovine PET-MRI for imaging high-grade glioma is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor [Phase 1, Phase 2]
ImmVira Pharma is planning a Phase I/IIa trial of C5252 for malignant glioma, with the study not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients [Phase 1]
A Phase 1 safety study evaluating repeated opening of the blood-brain barrier using the SonoCloud device to treat pediatric malignant brain …
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating simultaneous multinuclear metabolic MRI in patients with glioma, including newly diagnosed and re…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma [EARLY_Phase 1]
Early-phase trial evaluating the intratumoral metabolic impact of DFMO combined with AMXT-1501 in patients with diffuse or high-grade glioma…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM [Phase 1]
Phase 1 clinical trial evaluating a peptide-based tumor-associated antigen vaccine for glioblastoma, a malignant glioma. The study is curren…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma [Phase 1]
Phase 1 study of chlorotoxin-targeted CAR T cells targeting MMP2 in patients with recurrent glioblastoma and other recurrent gliomas. The tr…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Fitness and Nutrition in Glioma [NA]
This document reports a clinical trial update for a study on fitness and nutrition in malignant glioma. The trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas. [Phase 2]
Phase 2 clinical trial evaluating whether hydrogen-rich water improves quality of life in patients receiving radiotherapy for high-grade mal…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Imaging of Solid Tumors Using 18F-TRX [Phase 1]
A Phase 1 study is evaluating imaging of solid tumors with the radiotracer 18F-TRX. The trial is currently recruiting and includes prostate …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Fimepinostat in Treating Brain Tumors in Children and Young Adults [EARLY_Phase 1]
This is an early-phase 1 trial update on fimepinostat for pediatric and young adult brain tumors, including DIPG, recurrent anaplastic astro…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma [Phase 1]
Phase 1 clinical trial update for PEP-CMV in recurrent medulloblastoma and malignant glioma.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial [NA]
Clinical trial update for Proton Pulsed Reduced Dose Rate Radiotherapy (PPRDR) in recurrent CNS malignancies; the trial is currently recruit…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the safety and tolerability of Fb-PMT in patients with recurrent glioblastoma, with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas [NA]
A clinical trial comparing 18F-FET-PET/MRI planning to standard MRI planning for stereotactic radiotherapy in patients with malignant glioma…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases [NA]
Clinical trial comparing intraoperative sonography to fluorescence-guided resection for contrast-enhancing gliomas and brain metastases has …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases [NA]
This clinical trial update reports a recruitment-status study (NCT05474573) evaluating fluorescence- and ultrasound-guided eradication of co…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4) [Phase 3]
A Phase III clinical trial is evaluating resection efficacy using fluorescence-guided surgery with 5-ALA HCl versus conventional white-light…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: D2C7-IT With Atezolizumab for Recurrent Gliomas [Phase 1]
Phase 1 clinical trial update of D2C7-IT in combination with atezolizumab for recurrent malignant glioma; study currently active but not rec…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults [Phase 1]
Phase 1 clinical trial evaluating immunotherapy before and after surgery for recurrent or progressive high-grade glioma in children and youn…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: 5G-EMERALD: Amivantamab in Malignant Brain Tumours [Phase 1]
A Phase 1 clinical trial of amivantamab for malignant brain tumors, including glioblastoma and related gliomas, is currently recruiting in t…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) [Phase 1]
A Phase 1 clinical trial investigating a laparoscopically harvested omental autograft to bypass the blood-brain barrier in recurrent gliobla…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas
This clinical trial update outlines an integrated analysis of how embryonal tumors and gliomas respond to therapy and develop resistance, in…