Malaria
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Integrating Malaria Vaccine With Seasonal Malaria Chemoprevention in West Africa [Phase 4]
A Phase 4 clinical trial update indicates a study in West Africa evaluating integrating a malaria vaccine with seasonal malaria chemoprevent…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: IGHID 12334 - After the Flood: Optimal Strategies to Prevent Malaria Epidemics Caused by Severe Flooding [NA]
An update on the IGHID 12334 trial evaluating strategies to prevent malaria epidemics after severe flooding; the study is currently active b…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Infant Malaria Vaccine Schedule Optimization [Phase 2]
PATH is conducting a Phase 2 study to optimize the vaccination schedule for an infant malaria vaccine, and the trial is currently recruiting…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: DON in Pediatric Cerebral Malaria [Phase 1, Phase 2]
This entry notes an ongoing Phase 1/Phase 2 clinical trial evaluating DON for pediatric cerebral malaria, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Full Assessment of Clinical Transfusion Support
Clinical trial update noting the completion of a study on transfusion support in sickle cell anemia, with attention to malaria parasitaemia.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Monoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital Discharge [Phase 3]
Phase 3 clinical trial evaluating monoclonal antibodies to prevent malaria after hospital discharge in children with severe anaemia or sever…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa [Phase 4]
GlaxoSmithKline completed a Phase 4 epidemiology study on malaria transmission intensity in Sub-Saharan Africa. Results have been posted.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Post-discharge Malaria Chemoprevention Implementation Trial in Benin [Phase 4]
A Phase 4 post-discharge malaria chemoprevention trial in Benin is currently recruiting to evaluate strategies for preventing malaria after …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield [NA]
A completed clinical trial evaluating radical cure for vivax malaria among highly mobile and hard-to-reach populations in the Guyanese Shiel…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Optimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas [NA]
A completed University of Minnesota–sponsored clinical trial evaluating how to optimize the benefits and reduce risks of iron therapy in mal…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Permethrin-treated Baby-wraps for the Prevention of Malaria in Children [NA]
Completed clinical trial evaluating whether permethrin-treated baby wraps can prevent malaria in children.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso [Phase 1, Phase 2]
A completed Phase 1/2 trial in 5-17 month old children in Nanoro, Burkina Faso evaluated the safety, immunogenicity, and efficacy of the R21…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) [NA]
The INDIE-SMC trial led by the London School of Hygiene and Tropical Medicine has completed, investigating how antimalarial treatment affect…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults [Phase 2]
A Phase 2 clinical trial evaluating the safety and immunogenicity of the R21/Matrix-M malaria vaccine in healthy Thai adults has completed. …
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) [NA]
A clinical trial is investigating whether L-Arginine can prevent adverse pregnancy outcomes and is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Clinical Practices for Treating Severe Malaria Caused by P. Falciparum
This document provides an update on clinical practices for treating severe malaria caused by Plasmodium falciparum, based on completed trial…
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FDA approval · 2025-06-13FDA Approved: HYDROXYCHLOROQUINE — Supplemental Application (Chartwell RX, LLC)
The FDA approved a supplemental application for hydroxychloroquine (HYDROXYCHLOROQUINE) from Chartwell RX, LLC under an ANDA. The action upd…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Star Homes Project 2 [NA]
University of Oxford is conducting Star Homes Project 2 and currently recruiting participants for malaria, acute respiratory tract infection…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy [Phase 3]
This clinical trial update describes a Phase 3 study evaluating sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine for intermitte…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: EaveTubes for Vector Control [NA]
The University of Notre Dame is updating a clinical trial for the EaveTubes vector-control intervention targeting malaria, with the study cu…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Burden of Schistosomiasis and Soil-transmitted Helminth Infections in Schoolchildren in Banfora, Burkina Faso
This clinical trial update reports on the burden of schistosomiasis and soil-transmitted helminth infections among schoolchildren in Banfora…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Efficacy of Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Children Under 12 Years at Four Sentinel Sites in Mozambique [NA]
This completed clinical trial evaluates the efficacy of artemether-lumefantrine for treating uncomplicated Plasmodium falciparum malaria in …
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Repellents as Added Control Measure to Long Lasting Insecticidal Nets [NA]
This clinical trial evaluated repellents added to long-lasting insecticidal nets for malaria control. The study has completed.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia [Phase 3]
PATH-sponsored Phase 3 clinical trial in Ethiopia evaluating targeted antimalarial drug administration for seasonal migrant populations in t…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Pan-Malaria Transmission-Blocking Vaccine AnAPN1 [Phase 1]
Phase 1 trial of the AnAPN1 pan-malaria transmission-blocking vaccine has been completed.