Malaria
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Introduction of Polymerase Chain Reaction (PCR) in Microbiology and Parasitology
This clinical trial update notes the introduction of PCR methods in microbiology and parasitology, with the study currently recruiting for m…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults [Phase 1]
Phase 1 trial evaluated the safety and immunogenicity of PRIMVAC, a placental malaria vaccine candidate, in healthy adults and the study has…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Testing a Biometric Identification System to Improve Malaria Vaccine Completion [NA]
This clinical trial update from the University of Michigan describes testing a biometric identification system to improve completion rates o…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults [Phase 1]
Phase 1 trial update of the Plasmodium vivax Pvs230D1-EPA/Matrix-M malaria vaccine in healthy malaria-naive adults. The study evaluated safe…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: PDMC Implementation Trial in Kenya [Phase 4]
Phase 4 clinical trial in Kenya evaluating the real-world implementation of post-discharge malaria chemoprevention for children hospitalized…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Challenge Study to Assess the Blood-stage Efficacy of Full-length SUM-101 Malaria Vaccine Candidate [Phase 1]
Phase 1 challenge study update for SUM-101 malaria vaccine candidate; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi [Phase 4]
Phase 4 clinical trial in Malawi evaluating malaria prevention in schoolchildren to protect the wider community; the study is currently acti…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Pfs230D1 + R21 in Matrix-M1 in African School Children and Adults [Phase 2]
Phase 2 clinical trial evaluating an R21 malaria vaccine containing Pfs230D1 with the Matrix-M1 adjuvant for prevention of malaria transmiss…
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CLINICAL_TRIALS other · 2025-11-19Clinical Trial Update: Safety of Antimalarials in the FIRst trimEster [Phase 3]
Ongoing Phase 3 clinical trials are evaluating the safety of antimalarial drugs in the first trimester of pregnancy; the study is currently …
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: FocaL Mass Drug Administration for Vivax Malaria Elimination [Phase 3]
Phase 3 clinical trial evaluating focal mass drug administration to eliminate Plasmodium vivax malaria; recruitment is ongoing, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda [Phase 3]
A Phase 3 trial in Uganda evaluating optimal chemopreventive regimens to prevent malaria and improve birth outcomes has completed and posted…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Anti-malaria MAb in Kenyan Children [Phase 2]
Phase 2 trial evaluating an anti-malaria monoclonal antibody in Kenyan children has completed and posted results.
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Platelet-Directed Whole Blood Transfusion Strategy for Malaria [NA]
This clinical trial update describes ongoing recruitment for a study evaluating a platelet-directed whole blood transfusion strategy for sev…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants [Phase 1]
Phase 1 single-ascending-dose trial assessing safety, tolerability, and pharmacokinetics of MMV371 LAI in healthy participants; study comple…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months [Phase 2]
Phase 2 clinical trial to assess the safety and immunogenicity of a malaria vaccine in healthy children aged 5-60 months; recruitment is cur…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Knowledge and Attitude Among Healthcare Workers Towards Malaria Vaccine, Sudan 2025.
This completed clinical trial update assesses healthcare workers' knowledge and attitudes toward a malaria vaccine in Sudan. The study summa…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: L9LS MAb in Malian Infants [Phase 1]
Phase 1 trial update for the L9LS monoclonal antibody in Malian infants; the study investigating malaria prevention is active but not curren…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Study of Oral E1018 in Healthy Adult Participants [Phase 1]
Phase 1 study of oral E1018 in healthy adult participants to assess safety and tolerability in the context of malaria; the trial is currentl…
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EMA approval · 2025-09-04EMA Authorised: Eurartesim (piperaquine tetraphosphate;artenimol) — Alfasigma S.p.A.
The EMA has authorised Eurartesim for malaria treatment in the European Union. The product combines piperaquine tetraphosphate and artenimol…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria [Phase 1]
Phase 1 trial of an investigational RNA-based malaria vaccine by BioNTech assessed safety and immune responses; study completed and results …
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon
This clinical trial update reports the completion of a study led by Karolinska Institutet that investigates the relationship between diabete…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique [Phase 4]
Phase 4 trial in Mozambique evaluating the in vivo efficacy of four ACT regimens for malaria.
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FDA approval · 2025-08-18FDA Approved: PRIMAQUINE PHOSPHATE — Supplemental Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved a supplemental application for Primaquine Phosphate by Unichem Pharmaceuticals (USA), Inc., granting marketing authorization fo…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
This clinical trial update reports the completion and results of a comparative study on thrombocytopenia in Plasmodium vivax malaria versus …
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine
An observational study is being conducted to assess the effectiveness and safety of the R21/Matrix-M malaria vaccine, and the study is curre…