Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2) [Phase 2]
Phase 2 CAPTURE-2 study assessing the efficacy, safety, and pharmacokinetics of M5717 in combination with Pyronaridine for chemoprevention o…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of Ghana [NA]
An ongoing Ghana-based clinical trial is evaluating the feasibility of combining dihydroartemisinin-piperaquine with primaquine for malaria …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa [Phase 4]
Phase 4 clinical trial updating on optimizing malaria and HIV treatment in Africa; study currently recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Long-acting Spatial Emanators / Repellents (LASER) [NA]
This clinical trial update describes a study of long-acting spatial emanators/repellents (LASER) for malaria transmission and prevention, cu…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Characterizing Humoral Immune Response to Mosquito Bites [NA]
A completed University of Oxford clinical trial studied the humoral immune response to mosquito bites in the contexts of malaria and dengue …
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FDA approval · 2026-02-02FDA Approved: PRIMAQUINE PHOSPHATE — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application for Primaquine Phosphate from Sanofi-Aventis U.S. LLC, leading to a labeling update for the product.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: CHILD (Child Health and Infection With Low Density) Malaria [NA]
This update states that the CHILD malaria trial sponsored by the University of California, San Francisco has completed.
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Efficacy, Safety and Tolerability of KLU156 in Adults and Children With Uncomplicated P. Falciparum Malaria [Phase 3]
Phase 3 trial update showing efficacy, safety and tolerability of KLU156 in adults and children with uncomplicated Plasmodium falciparum mal…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Severe Malaria in Remote Areas- Closing the Evidence Gap
Enrollment is ongoing by invitation for a study addressing severe malaria in remote areas to close the evidence gap.
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention
A completed clinical trial evaluating multiple doses of intermittent preventive treatment in infants (IPTi) for malaria.
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya
A completed clinical trial conducted in western Kenya examined health-system implementation and molecular surveillance across multiple first…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating safety, pharmacokinetics, and the transmission-reducing activity of the monoclonal antibody TB31F in …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women [NA]
This update reports the completion of a malaria mass drug administration trial assessing its effect on malaria prevalence in children under …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
An ongoing recruitment update for a One Health study evaluating the risk of community spread of multiple endemic infectious diseases. The st…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Clinical Prediction Models for Pediatric In-Hospital Death Risk in Congolese Severe Malaria Children Using Machine Learning Based-Algorithms
This completed clinical trial from the University of Kinshasa evaluates machine learning-based prediction models to estimate in-hospital mor…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics [Phase 4]
A Phase 4 trial from Duke University is investigating a high-sensitivity rapid malaria test in early pregnancy to improve neonatal health ou…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: LLIN Evaluation in Uganda Project (LLINEUP3) [NA]
The LLIN Evaluation in Uganda Project (LLINEUP3) trial evaluating long-lasting insecticidal nets for malaria prevention in Uganda has comple…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission [Phase 4]
Phase 4 clinical trial update evaluating intermittent preventive treatment of malaria in school-age children to reduce community transmissio…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia
A clinical trial update from NIAID describing a study of malaria transmission dynamics in humans and mosquitoes in Liberia, currently active…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: RTSS Vaccine and PBO Net Impact on Malaria Infection and Transmission in Malawi
This completed clinical trial in Malawi evaluated the impact of the RTS,S malaria vaccine (RTS,S/AS01) with insecticide-treated bed nets on …
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Vivax Elimination With Tafenoquine (VET) Study [Phase 4]
Phase 4 clinical trial update evaluating tafenoquine for eliminating Plasmodium vivax malaria; the study has completed.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency [NA]
The study investigates whether iron treatment in Kenyan infants with iron deficiency influences malaria outcomes and the response to measles…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria [Phase 4]
Phase 4 pharmacokinetic study evaluating intravenous artesunate in children with severe malaria has completed; the trial was sponsored by NI…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: MDA and Targeted Control Against Plasmodium Carriage in the Sahel [NA]
A clinical trial in the Sahel is evaluating targeted control against Plasmodium carriage in malaria, with the study currently active but not…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum [Phase 1]
Phase 1b PK/PD and safety data for MMV367 in experimentally induced blood-stage Plasmodium falciparum infection in healthy adults; the study…