Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-03-27Clinical Trial Update: Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine [Phase 2]
Phase 2 trial follow-up assesses two-year safety and immunogenicity of the GSK 257049 malaria vaccine in children, with results posted after…
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy [Phase 3]
Phase 3 trial comparing two regimens of artemether-lumefantrine for treating malaria in pregnancy; the study has completed.
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CLINICAL_TRIALS trial_result · 2014-03-21Clinical Trial Update: Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease [Phase 1, Phase 2]
This entry reports the completion status of a Phase 1/2 trial evaluating intermittent preventive treatment for malaria in people with sickle…
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CLINICAL_TRIALS trial_result · 2014-03-21Clinical Trial Update: Preserving ACTs - Text Reminders to Increase Adherence to ACT Treatment [NA]
Completed clinical trial assessing text message reminders to increase adherence to artemisinin-based combination therapy for malaria.
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CLINICAL_TRIALS trial_result · 2014-03-20Clinical Trial Update: Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy [NA]
This clinical trial update reports the completion of a study evaluating alternative antimalarial drugs for malaria in pregnancy.
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Long-term Iron Supplements and Malaria Risk in Early Pregnancy: a Randomized Controlled Trial [NA]
This entry notes the completion of a randomized controlled trial investigating whether long-term iron supplementation affects malaria risk i…
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: Parasite Clearance Time and Time to Recurrent Infection Following Treatment With Artemether/Lumefantrine [Phase 4]
Phase 4 clinical trial update evaluating parasite clearance time and time to recurrent infection after treatment with Artemether/Lumefantrin…
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CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: Pharmacokinetic Study of Multi-dose Chloroquine [Phase 4]
A Phase 4 pharmacokinetic study evaluated multi-dose chloroquine for malaria; the trial has been completed.
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FDA approval · 2014-03-05FDA Approved: DOXYCYCLINE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approves Lupin Pharmaceuticals' generic doxycycline (DOXYCYCLINE) under an original application.
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CLINICAL_TRIALS trial_result · 2014-02-26Clinical Trial Update: HCU: Can VHVs Trained in ICCM Improve Care for Children [NA]
A University of Calgary trial evaluated whether volunteer health workers trained in ICCM can improve care for children with diarrhea, pneumo…
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FDA approval · 2014-02-25FDA Approved: PRIMAQUINE PHOSPHATE — Original Application (Unichem Pharmaceuticals (USA), Inc.)
The FDA approved the original application for PRIMAQUINE PHOSPHATE, a generic antimalarial manufactured by Unichem Pharmaceuticals (USA), In…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: a Randomized Controlled Trial [Phase 1, Phase 2]
This update reports the completion of a randomized Phase 1/2 trial evaluating inhaled nitric oxide as adjunctive therapy for severe malaria.
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CLINICAL_TRIALS trial_result · 2014-02-17Clinical Trial Update: Impact of Malaria Prevention on Health and Education in Kenyan Schoolchildren [NA]
The completed trial evaluated how malaria prevention affected health outcomes and education in Kenyan schoolchildren. It focused on malaria …
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Initial Study of Malaria Vaccine Pfs25-EPA/Alhydrogel(Registered Trademark) [Phase 1]
Phase 1 clinical trial evaluating the malaria vaccine Pfs25-EPA/Alhydrogel has been completed.
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) [Phase 3]
Phase 3 trial evaluating immunogenicity of the Hepatitis B antigen of GSK's candidate malaria vaccine has completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: Examination of ACT Implementation in a Vivax / Falciparum Co-endemic Area [Phase 4]
Phase 4 clinical trial evaluating implementation of artemisinin-based combination therapy for malaria in vivax- and falciparum-endemic areas…
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children [Phase 3]
A Phase 3 trial evaluating four artemisinin-based combination therapies for treating uncomplicated malaria in African children has completed…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine [Phase 4]
Phase 4 clinical trial update evaluating surveillance and treatment of malaria with dihydroartemisinin-piperaquine plus primaquine; the stud…
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis [NA]
This clinical trial update reports the outcomes of an experimental human malaria infection study in volunteers immunized with Plasmodium fal…
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CLINICAL_TRIALS trial_result · 2014-01-16Clinical Trial Update: Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina Faso [Phase 4]
Phase 4 pharmacokinetic study of dihydroartemisinin-piperaquine in children with uncomplicated malaria in Burkina Faso. The trial provides p…
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CLINICAL_TRIALS trial_result · 2014-01-15Clinical Trial Update: Exposure of Naive and Pre-immune Subjects to P. Vivax Challenge [Phase 1, Phase 2]
Completion of a Phase 1/2 clinical trial evaluating exposure of malaria-naive and pre-immune subjects to Plasmodium vivax in a malaria chall…
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Efficacy of Malaria Vaccines in Kenyan Adults [Phase 2]
This document reports an update on the efficacy results from Phase 2 clinical trials of malaria vaccines tested in Kenyan adults.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Efficacy of Candidate Malaria Vaccines in Senegalese Adults [Phase 2]
Phase 2 clinical trial in Senegalese adults evaluated the efficacy of candidate malaria vaccines and has completed, with results reported.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Children in a Malaria Endemic Area [Phase 1]
Phase 1 trial evaluating AdCh63 ME-TRAP and MVA ME-TRAP malaria vaccines in healthy children in a malaria-endemic area has been completed.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) [Phase 3]
Phase 3 TRANSACT2 trial reports on treatment efficacy and malaria transmission after artemisinin-based combination therapy.