Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-10-22Clinical Trial Update: Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria [Phase 3]
Phase 3 trial evaluating whether artemisinin-based combination therapy together with quinine affects treatment failure and resistance in unc…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: Chloroquine and Post Malaria Anaemia Study [NA]
This trial update reports the completion of a study evaluating chloroquine for post-malaria anemia with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-09-23Clinical Trial Update: Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania [NA]
A completed clinical trial in Tanzania assessed schistosome and intestinal worm infections and their impact on malaria morbidity among schoo…
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: Adenovirus Vaccine for Malaria [Phase 1]
Phase 1 clinical trial of an adenovirus-based malaria vaccine sponsored by NIAID has completed. The trial focused on Plasmodium falciparum i…
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CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults [Phase 1]
Phase 1 study documenting controlled human malaria infection via intradermal injection of Plasmodium falciparum sporozoites in Tanzanian adu…
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CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: Clinical Trial of the PfSPZ Vaccine [Phase 1]
Phase 1 clinical trial of the PfSPZ malaria vaccine by Sanaria has completed.
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria [Phase 1, Phase 2]
This document reports safety and efficacy findings from Phase 1/Phase 2 trials of the RTS,S AS02A/AS01B malaria vaccine.
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FDA approval · 2014-08-12FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for COARTEM (artemether and lumefantrine) from Novartis Pharmaceuticals Corporation, detailing t…
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CLINICAL_TRIALS trial_result · 2014-08-08Clinical Trial Update: Malaria Challenge With NF54 Strain [Phase 1]
A Phase 1 malaria-challenge trial using the Plasmodium falciparum NF54 strain has completed.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo [Phase 1]
This completed Phase 1 study investigated the pharmacokinetics and pharmacodynamics of artesunate in pregnant women with malaria in the Demo…
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Safe Pregnancy by Infectious Disease Control
Clinical trial update on Safe Pregnancy by Infectious Disease Control (NCT00489619), sponsored by NICHD Global Network, with completed statu…
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CLINICAL_TRIALS research · 2014-07-25Clinical Trial Update: Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania
INDEPTH Network reports the introduction of Eurartesim for malaria in Burkina Faso, Mozambique, Ghana, and Tanzania.
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CLINICAL_TRIALS trial_result · 2014-07-23Clinical Trial Update: Molecular Assessment of Artemisinin Resistance Markers in Eastern and Western Border Areas of Myanmar
The completed trial in Myanmar assessed molecular markers of artemisinin resistance in malaria and reported on Day-3 parasitaemia and resist…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children [Phase 4]
Phase 4 trial update on the in vivo efficacy of two malaria drug combinations, artemether-lumefantrine and amodiaquine-artesunate, in Mozamb…
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CLINICAL_TRIALS trial_result · 2014-06-06Clinical Trial Update: Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso [Phase 1]
Phase 1 trial of an Ad35-based circumsporozoite malaria vaccine in Burkina Faso has completed, evaluating safety and immunogenicity.
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FDA label_change · 2014-06-04FDA Approved: ATOVAQUONE AND PROGUANIL HYDROCHLORIDE PEDIATRIC — Supplemental Application (Glenmark Pharmaceuticals Inc.,USA)
FDA supplemental approval adds pediatric labeling for atovaquone and proguanil hydrochloride, expanding its use to pediatric patients.
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CLINICAL_TRIALS trial_result · 2014-06-03Clinical Trial Update: Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers [Phase 2]
Phase 2 study evaluating reproducibility of a sporozoite challenge model for Plasmodium vivax in human volunteers; results posted after comp…
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CLINICAL_TRIALS other · 2014-05-30Clinical Trial Update: Home Management of Malaria and Pneumonia [Phase 4]
This is an update on a Phase 4 clinical trial studying home management of malaria and pneumonia, which has completed.
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FDA approval · 2014-05-27FDA Approved: ATOVAQUONE AND PROGUANIL HYDROCHLORIDE — Original Application (Mylan Pharmaceuticals Inc.)
FDA approves a generic version of atovaquone and proguanil hydrochloride for the treatment and prevention of malaria (ANDA 202362, Mylan).
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Pharmacology of Antimalarial Therapy With or Without Antiretroviral Therapy [Phase 4]
Phase 4 clinical trial evaluating the pharmacology of antimalarial therapy with or without antiretroviral therapy; the study status is TERMI…
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FDA label_change · 2014-05-06FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for COARTEM (artemether and lumefantrine) submitted by Novartis, resulting in changes to the pro…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)
This completed clinical trial evaluated the performance of the Fyodor Urine Malaria Test (UMT) for detecting malaria.
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FDA approval · 2014-04-17FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for COARTEM (artemether and lumefantrine) from Novartis Pharmaceuticals Corporation, representing an…
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy [Phase 4]
Phase 4 trial comparing intermittent preventive treatment versus scheduled screening and treatment for malaria in pregnancy has completed.
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Impact of School-based Delivery of Long Lasting Insecticide Nets [NA]
A completed clinical trial assessing school-based delivery of long-lasting insecticide nets to reduce malaria burden.