Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Weekly Dosing of Malarone ® for Prevention of Malaria [Phase 2]
Phase 2 trial evaluating weekly dosing of Malarone (atovaquone-proguanil) for prevention of malaria. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®) [Phase 4]
Phase 4 community-setting trial evaluating outcomes after systematic treatment with COA566 (Coartem) in symptomatic carriers of malaria due …
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FDA approval · 2013-11-18FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for COARTEM (artemether and lumefantrine) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1 [Phase 1, Phase 2]
A Phase I/IIa sporozoite challenge trial conducted by the University of Oxford to evaluate malaria vaccine approaches using ChAd63 and MVA v…
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CLINICAL_TRIALS research · 2013-11-08Clinical Trial Update: Safety and Efficacy of Primaquine for P. Vivax [NA]
An update on a clinical trial evaluating the safety and efficacy of primaquine for malaria, with phase and current status not reported.
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CLINICAL_TRIALS trial_result · 2013-11-01Clinical Trial Update: Impact of Enhanced Health Facility Care in Uganda [Phase 4]
A Phase 4 clinical trial in Uganda evaluated the impact of enhanced health facility care on malaria outcomes. The study has completed.
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight [NA]
A completed clinical trial evaluated whether administering Ready to Use Therapeutic Food (RUTF) after a malaria episode influences weight ou…
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection [NA]
Clinical trial update evaluating whether nutritional supplementation can prevent malnutrition in children with infections, including malaria…
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CLINICAL_TRIALS trial_result · 2013-10-11Clinical Trial Update: Interactions Between HIV and Malaria in African Children [Phase 3]
Phase 3 trial evaluating interactions between HIV infection and malaria in African children has completed; the update summarizes the study r…
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CLINICAL_TRIALS research · 2013-10-08Clinical Trial Update: Evaluation of the Efficacy of Artemisinin Combination Therapy in Kenya [Phase 3]
This update covers a Phase 3 clinical trial in Kenya evaluating the efficacy of artemisinin-based combination therapy for malaria; the curre…
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CLINICAL_TRIALS trial_result · 2013-09-24Clinical Trial Update: Efficacy of Iron Fortified Complementary Food and IPT of Malaria in Young Children in Côte d'Ivoire [NA]
A completed clinical trial in Côte d'Ivoire evaluated the efficacy of iron-fortified complementary food and intermittent preventive treatmen…
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CLINICAL_TRIALS trial_result · 2013-09-13Clinical Trial Update: Malaria Treatment With Injectable ArteSunate
A completed clinical trial evaluating an injectable ArteSunate for treatment of severe malaria.
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CLINICAL_TRIALS trial_result · 2013-09-13Clinical Trial Update: Sanaria™ PfSPZ Challenge Vaccine [Phase 1]
Phase 1 trial update for the Sanaria PfSPZ Challenge Vaccine targeting malaria; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-08-23Clinical Trial Update: Artemisinin Resistance in Bangladesh [NA]
The trial update indicates that the study on artemisinin resistance in Bangladesh has completed.
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CLINICAL_TRIALS trial_result · 2013-07-29Clinical Trial Update: Safety and Immunogenicity of Novel Vaccination Schedules With Malaria Vaccines AdCh63 ME-TRAP and MVA ME-TRAP [Phase 1]
A Phase 1 clinical trial reports safety and immunogenicity data for novel vaccination schedules using malaria vaccines AdCh63 ME-TRAP and MV…
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FDA approval · 2013-07-26FDA Approved: MEFLOQUINE HYDROCHLORIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for mefloquine hydrochloride from Chartwell RX, LLC (ANDA 076175).
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FDA approval · 2013-07-26FDA Approved: MEFLOQUINE HYDROCHLORIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved Teva Pharmaceuticals USA, Inc.'s supplemental application for mefloquine hydrochloride, finalizing approval of a generic antima…
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CLINICAL_TRIALS trial_result · 2013-07-25Clinical Trial Update: The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level [Phase 4]
This Phase 4 trial update examines whether rapid diagnostic tests for malaria can better target artemisinin-based combination therapies at t…
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CLINICAL_TRIALS trial_result · 2013-07-24Clinical Trial Update: The Optimal Timing Of Primaquine To Prevent Malaria Transmission After Artemisinin-Combination Therapy [Phase 4]
This Phase 4 clinical trial investigates the optimal timing of primaquine after artemisinin-based combination therapy to prevent malaria tra…
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CLINICAL_TRIALS trial_result · 2013-07-08Clinical Trial Update: Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants [Phase 2]
Phase 2 trial update for a malaria vaccine candidate in Tanzanian infants assessing safety, immunogenicity, and efficacy.
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CLINICAL_TRIALS research · 2013-06-13Clinical Trial Update: Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / Lumefantrine [Phase 1]
Phase 1 trial update examining potential drug-drug interactions between HIV antiretrovirals (etravirine or darunavir/ritonavir) and the anti…
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CLINICAL_TRIALS trial_result · 2013-06-06Clinical Trial Update: Drug Interaction Study Between Antimalarial and Anti-HIV Medications [Phase 1]
This Phase 1 trial update reports the completion of a drug interaction study between antimalarial and anti-HIV medications. The study invest…
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CLINICAL_TRIALS trial_result · 2013-06-06Clinical Trial Update: Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug Combinations [Phase 1]
Phase 1 study assessing pharmacokinetic interactions between antiretroviral agents and antimalarial drug combinations; status completed.
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CLINICAL_TRIALS trial_result · 2013-05-29Clinical Trial Update: Prenatal Iron and Malaria Study [Phase 4]
Phase 4 clinical trial evaluating prenatal iron supplementation in relation to malaria outcomes has completed.
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CLINICAL_TRIALS trial_result · 2013-05-28Clinical Trial Update: Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and Syringe [NA]
This is an update on a clinical trial optimizing controlled human malaria infection using Plasmodium falciparum sporozoites delivered by nee…