Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers [Phase 1]
Phase 1 open-label pharmacokinetic study assessing OZ439 in combination with Piperaquine, using OZ439+TPGS granules for oral suspension with…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Experimental Human Malaria Infection by PfSPZ [Phase 1]
Phase 1 trial update reporting that the experimental PfSPZ vaccine study in humans reached completion, evaluating safety and immune response…
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FDA approval · 2015-04-16FDA Approved: PRIMAQUINE PHOSPHATE — Supplemental Application (Sanofi-Aventis U.S. LLC)
The FDA approved a supplemental application for Primaquine phosphate submitted by Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS research · 2015-04-16Clinical Trial Update: Evaluating the Ottawa Malaria Decision Aid [NA]
This document provides an update on a clinical trial evaluating the Ottawa Malaria Decision Aid.
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: A Study of Safety and Immunogenicity of a Malaria Vaccine Candidate [Phase 1]
A Phase 1 study evaluating safety and immunogenicity of a malaria vaccine candidate has completed. The sponsor reported completion of a Phas…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children [NA]
A completed clinical trial assessing whether repeated anthelmintic treatment influences the risk of malaria in Kenyan schoolchildren.
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CLINICAL_TRIALS trial_result · 2015-04-09Clinical Trial Update: P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine [Phase 3]
Phase 3 trial comparing artesunate-mefloquine versus chloroquine for uncomplicated malaria due to Plasmodium knowlesi has completed.
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State [Phase 1]
This Phase 1 healthy volunteer study assessed the pharmacokinetics of an oral piperaquine-based antimalarial combination containing OZ439 an…
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers [Phase 1]
Phase 1 safety, tolerability, and pharmacokinetics update for co-administered OZ439 and mefloquine in healthy volunteers. The study was term…
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP) [Phase 1]
Phase 1 study assessing the bioavailability of oral OZ439 prototype formulations when administered with Piperaquine Phosphate (PQP) in malar…
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: A Dose-escalation Study to Investigate Safety and Toleration of OZ439 [Phase 1]
Phase 1 dose-escalation trial evaluating safety and tolerability of OZ439 in malaria, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-20Clinical Trial Update: Effectiveness of Malaria Treatment in Mexico [Phase 4]
A Phase 4 clinical trial evaluating the effectiveness of a malaria treatment conducted in Mexico has completed.
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CLINICAL_TRIALS trial_result · 2015-03-10Clinical Trial Update: Sustainable Financial Incentives To Improve Prescription Practices For Malaria [NA]
A completed clinical trial assessing whether sustainable financial incentives can improve malaria prescription practices.
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire [Phase 4]
A Sanofi-sponsored Phase 4 trial evaluating artesunate plus amodiaquine for malaria in Cote d'Ivoire has completed.
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates [Phase 1, Phase 2]
A Challenge Study evaluating the protective efficacy of two malaria vaccine candidates in Phase 1/2 has completed.
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: Malaria and the Safety of Iron Supplements and Iron Fortification [NA]
This completed clinical trial update examines the safety of iron supplementation and iron fortification in the context of malaria, focusing …
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CLINICAL_TRIALS trial_result · 2015-02-03Clinical Trial Update: Evaluation of Insecticide Treated Nets and Wall Liners for the Prevention of Malaria [Phase 3]
A Phase 3 trial evaluated insecticide-treated nets and wall liners for malaria prevention and has completed.
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FDA approval · 2015-01-20FDA Approved: COARTEM — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for COARTEM (artemether and lumefantrine) from Novartis Pharmaceuticals Corporation to update labeli…
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FDA approval · 2015-01-20FDA Approved: HYDROXYCHLOROQUINE SULFATE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for hydroxychloroquine sulfate submitted by Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2015-01-19Clinical Trial Update: Phase2a Primaquine Dose Escalation Study [Phase 2]
A Phase 2a dose-escalation trial of primaquine for malaria has completed, providing early safety and dosing information.
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: Stimulating Private Sector Malaria Control [NA]
Clinical trial update indicating completed study on malaria with results posted.
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: Adjuvanting Viral Vectored Malaria Vaccines With Matrix M [Phase 1]
Phase 1 trial evaluating Matrix-M adjuvant with Oxford viral-vectored malaria vaccines (ChAd63-MVA ME-TRAP); the study has completed.
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum Strains [NA]
This clinical trial update reports a completed study of controlled human malaria infection in which participants were bitten by mosquitoes i…
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CLINICAL_TRIALS research · 2014-11-19Clinical Trial Update: A Cluster-randomised Trial of Interventions to Improve Antimalarial Prescribing With Malaria Tests [NA]
This entry notes that a cluster-randomized trial aiming to improve antimalarial prescribing with malaria testing has completed.
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CLINICAL_TRIALS trial_result · 2014-11-17Clinical Trial Update: Micronutrients and Child Health Study [Phase 3]
A Phase 3 clinical trial evaluating micronutrient supplementation for child health in malaria-affected populations has completed.