Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-08-20Clinical Trial Update: Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali [Phase 1]
Phase 1 trial assessing safety, immunogenicity, and protective efficacy of two regimens of radiation-attenuated PfSPZ vaccine in healthy adu…
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine [Phase 1]
Phase 1 trial update evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of ruxolitinib with artemether-lumefantrine for…
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon [Phase 3]
Phase 3 trial update for an artemisinin-based combination therapy in Cameroon for malaria; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults [Phase 1]
Phase 1 trial evaluating a malaria protein vaccine (FMP012) and PfCelTOS in malaria-naive adults has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-26Clinical Trial Update: Improving Anti-malarial Treatment Options in Guinea-Bissau - Part A [Phase 4]
Phase 4 clinical trial evaluating improvements in anti-malarial treatment options in Guinea-Bissau has completed.
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1 [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1/Phase 2 results for the NMRC-M3V-Ad-PfCA vaccine targeting Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2021-04-14Clinical Trial Update: Prevention of Malaria in HIV-uninfected Pregnant Women and Infants [Phase 3]
Phase 3 trial update on prevention of malaria in HIV-uninfected pregnant women and infants; results posted.
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CLINICAL_TRIALS trial_result · 2021-04-09Clinical Trial Update: Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model [Phase 1]
Phase 1 trial assessing safety, tolerability, and chemoprotective activity of P218 in a PfSPZ Challenge malaria model has completed with pos…
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde [Phase 4]
Phase 4 trial evaluating effectiveness and safety of artesunate-amodiaquine and artemether-lumefantrine for treating malaria in Yaounde, com…
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CLINICAL_TRIALS trial_result · 2021-03-30Clinical Trial Update: Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 [Phase 1]
Phase 1 clinical trial assessing infectivity equivalence between current and new lots of Plasmodium falciparum NF54 strain; completed with p…
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) [Phase 4]
Phase 4 trial evaluating three artemisinin-based combinations for uncomplicated malaria in children in Burkina Faso.
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Malaria Elimination Pilot Study in Military Forces in Cambodia [Phase 4]
A Phase 4 clinical trial update for a malaria elimination pilot study conducted with military forces in Cambodia.
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia [Phase 4]
Phase 4 trial comparing atovaquone-proguanil vs. artesunate-atovaquone-proguanil for malaria in Cambodia.
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: Efficacy of a Synthetic Vaccine Derived From Plasmodium Vivax Circumsporozoite Protein (PvCS) in naïve and Semi-immune Volunteers [Phase 2]
Phase 2 clinical trial assessing a synthetic PvCS-derived vaccine for malaria in naive and semi-immune volunteers.
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Household-level Impact of IPT of Malaria in Schoolchildren [Phase 3]
Phase 3 clinical trial update examining household-level impact of intermittent preventive therapy for malaria in schoolchildren.
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating malaria vaccines for safety, immune response, and protection; study completed.
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration [Phase 4]
Phase 4 trial comparing reactive case detection versus reactive drug administration for malaria elimination; completed.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania [Phase 2]
Phase 2 trial update evaluating the cardiac safety of dihydroartemisinin-piperaquine in pregnant women with malaria in Tanzania.
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CLINICAL_TRIALS trial_result · 2020-12-11Clinical Trial Update: Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults. [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of RTS,S/AS02A and RTS,S/AS01B malaria vaccines in malaria-experienced adults.
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial assessing artefenomel and ferroquine for uncomplicated Plasmodium falciparum malaria with pharmacokinetics and parasiticidal a…
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CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected Patients [Phase 4]
A Phase 4 trial update evaluating drug interaction between atovaquone and antiretroviral agents in HIV-1 infected patients completed.
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CLINICAL_TRIALS trial_result · 2020-11-12Clinical Trial Update: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 [NA]
Clinical trial update for TESTsmART trial AIM 1 focusing on malaria diagnostic testing and subsidies for ACTs in retail settings; study comp…
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CLINICAL_TRIALS trial_result · 2020-11-03Clinical Trial Update: Malaria High-Risk Populations in Namibia [Phase 4]
Phase 4 clinical trial update focused on malaria in high-risk populations in Namibia has completed.
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria [Phase 2]
Phase 2 pediatric pharmacokinetics, safety, and efficacy study of tafenoquine for Plasmodium vivax malaria has been completed with results p…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial evaluating ferroquine and artefenomel for uncomplicated Plasmodium falciparum malaria was terminated; results posted in 2020.