Malaria
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates
Clinical trial update detailing laboratory evaluation and in-vitro testing of pregnancy malaria vaccine candidates, with recruitment current…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
This clinical trial update notes that healthy volunteers are being screened for investigational antimalarial drugs, malaria vaccines, and co…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda [Phase 1]
Phase 1 trial update on the safety and pharmacokinetics of MMV371 LAI in healthy adults and adolescents in Rwanda; the study is not yet recr…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays [Phase 1]
Phase 1 clinical trial in healthy malaria-naive adults to assess the safety and infectivity of a Plasmodium vivax challenge agent and to eva…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
NIAID-sponsored clinical trial update indicates recruitment is ongoing to collect human biospecimens for basic and clinical research into gl…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad [Phase 4]
Phase 4 clinical trial update evaluating two strategies for administering the R21-Matrix M malaria vaccine in Chad during seasonal transmiss…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) [Phase 3]
Phase 3 clinical trial update for the malaria treatment dihydroartemisinin-piperaquine in children (MIC-DroP); the study is active but not c…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ [Phase 1]
Phase 1 study of escalating-dose, multi-prime R21/Matrix-M malaria vaccine is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
A clinical trial in Mali is investigating how host and parasite factors influence susceptibility to malaria infection and disease during pre…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults [Phase 1]
Phase 1 clinical trial in healthy adults assessing the safety and pharmacology of a fixed-dose combination of piperaquine, pyronaridine, and…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso
The clinical trial NCT04650815 on malaria transmission in humans and mosquitoes in Sabou, Burkina Faso has completed. Sponsored by NIAID, th…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar [Phase 3]
Phase 3 clinical trial evaluating serological testing and treatment for malaria caused by Plasmodium vivax and Plasmodium falciparum in Ethi…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
A National Institute of Allergy and Infectious Diseases sponsored clinical trial evaluating how to evaluate, treat, and monitor patients wit…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: R21/MM Dosing, Presentations, and Preservatives [Phase 4]
This clinical trial update covers Phase 4 dosing for the R21/MM malaria vaccine, along with recent presentations and preservatives used in t…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Pregnancy Registry in Mali
A pregnancy registry trial in Mali sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) is currently recruiting to…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 With Matrix-M in Combination With R21/Matrix-M [Phase 2]
Phase 2 study evaluating malaria vaccines R78C and RH5.1 with the Matrix-M adjuvant, in combination with R21/Matrix-M, is currently active b…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine) [Phase 1]
Phase 1 clinical trial update describing a study of three malaria vaccine candidates (R78C, RH5.1, and the multi-stage R21/Matrix-M) from th…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Non-invasive Malaria Diagnostic Data Collection in Ethiopia
This clinical trial aims to collect non-invasive malaria diagnostic data in Ethiopia. Recruitment is not yet underway.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Leveraging the Seasonal Malaria Chemoprevention Platform to Address Malaria and Malnutrition [NA]
An update on a clinical trial that uses the Seasonal Malaria Chemoprevention platform to address malaria and malnutrition through an integra…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria [Phase 2]
A Phase 2 clinical study is evaluating the safety and rapid anti-malarial activity of combining SJ733 with tafenoquine for radical cure of P…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Dose Finding Trial of R21/Matrix-M in School Children [Phase 2]
A Phase 2 dose-finding trial of the R21/Matrix-M malaria vaccine in schoolchildren is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe Adults [Phase 2]
A Phase 2 field trial of Sanaria's PfSPZ-LARC2 malaria vaccine in Burkinabe adults is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease
A clinical trial is evaluating whether malaria vaccines can reduce the risk of invasive non-typhoidal Salmonella disease, with recruitment o…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: L9LS in Women of Childbearing Potential in Mali [Phase 2]
A Phase 2 clinical trial evaluating L9LS for malaria in women of childbearing potential in Mali is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Investigating the Pharmacology of Tafenoquine in Papua New Guinean Children With Uncomplicated Malaria [Phase 4]
Phase 4 clinical trial examining the pharmacology of tafenoquine in Papua New Guinean children with uncomplicated malaria. The study is not …