Malaria
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CLINICAL_TRIALS trial_result · 2026-08-28Clinical Trial Results: A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria [Phase 1, Phase 2]
Phase 1/2 trial results for an investigational RNA-based malaria vaccine assessing safety, efficacy, and immune responses were completed wit…
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Results: Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria [Phase 4]
Phase 4 pharmacokinetic study evaluating intravenous artesunate in children with severe malaria completed, with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-12Clinical Trial Results: Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults [Phase 1]
Phase 1 trial assessing safety, tolerability, pharmacokinetics, and protective efficacy of MAM01 in healthy adults for malaria.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Update: Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) [Phase 3]
Phase 3 clinical trial update evaluating dihydroartemisinin-piperaquine for modifying immunity in children with malaria; study status is act…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: First-in-Human PfSPZ-LARC2 Vaccination/CHMI [Phase 1]
First-in-human Phase 1 trial update for the PfSPZ-LARC2 malaria vaccine (CHMI), sponsored by NIAID, currently not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) [Phase 1]
Phase 1 safety evaluation of the PfSPZ Vaccine in pregnant women in Mali (MalVIP1) is currently suspended.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso [Phase 1]
A Phase 1 safety trial testing age de-escalation of the PfSPZ-LARC2 malaria vaccine in Burkina Faso has completed, sponsored by Sanaria Inc.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating an investigational RNA-based malaria vaccine for safety, efficacy, and immune responses.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial evaluating intravenous cipargamin in severe malaria has completed and posted results, detailing efficacy, safety, tolerability…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Xpert® Tropical Fever Test on GeneXpert® Edge X System
A clinical trial update indicates Cepheid is enrolling by invitation to evaluate the Xpert Tropical Fever Test on the GeneXpert Edge X Syste…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines [Phase 1]
Phase 1 study evaluating the safety and immunogenicity of a single-vial R21/Matrix-M malaria vaccine, co-administered with EPI vaccines; the…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire [NA]
Clinical trial evaluating the efficacy of two next-generation insecticide-treated nets for malaria control in Cote d'Ivoire; sponsor London …
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
A completed NIAID-sponsored trial assessing malaria (and other parasites) in pregnant women and children in Margibi and Montserrado counties…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX
A completed clinical trial (IMMETASEX) investigating host immune and metabolic determinants of sexual conversion in Plasmodium parasites to …
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Study Assessing the Safety, Efficacy, and Impact of GlaxoSmithKline Biologicals' RTS, S/AS01E Malaria Vaccine in Young Children Across Sub-Saharan Africa
Completed clinical trial assessing safety, efficacy, and impact of GlaxoSmithKline's RTS,S/AS01E malaria vaccine (Mosquirix) in young childr…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat. [Phase 4]
Phase 4 clinical trial update from MAHAN Trust reports completion of a mortality control program targeting economically productive adults in…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali [Phase 2]
Phase 2 clinical trial update on the safety, immunogenicity and efficacy of the R21/Matrix-M1 malaria vaccine in healthy women of childbeari…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV [Phase 1]
Phase 1 trial assessing safety and immunogenicity of the malaria vaccine candidate R21/Matrix-M in African children living with HIV has comp…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy [EARLY_Phase 1]
This is an early Phase 1 clinical trial evaluating focal mass drug administration to prevent malaria during pregnancy. The trial is not yet …
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Dose-Escalating Study of Pfs230D1 in Combination With R21 in Matrix-M in African Adults [Phase 1]
A Phase 1 dose-escalation trial evaluating Pfs230D1 with the R21 malaria vaccine in Matrix-M adjuvant in African adults has completed.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2) [Phase 2]
Phase 2 CAPTURE-2 study assessing the efficacy, safety, and pharmacokinetics of M5717 in combination with Pyronaridine for chemoprevention o…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Characterizing Humoral Immune Response to Mosquito Bites [NA]
A completed University of Oxford clinical trial studied the humoral immune response to mosquito bites in the contexts of malaria and dengue …
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Efficacy, Safety and Tolerability of KLU156 in Adults and Children With Uncomplicated P. Falciparum Malaria [Phase 3]
Phase 3 trial update showing efficacy, safety and tolerability of KLU156 in adults and children with uncomplicated Plasmodium falciparum mal…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention
A completed clinical trial evaluating multiple doses of intermittent preventive treatment in infants (IPTi) for malaria.
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya
A completed clinical trial conducted in western Kenya examined health-system implementation and molecular surveillance across multiple first…