Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-04-22Clinical Trial Update: Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon [Phase 4]
Phase 4 trial update assessing the efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in malaria.
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for Treating Malaria [Phase 4]
Phase 4 trial assessing the effectiveness and safety of two artemisinin-based combination therapies for malaria has completed.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine [Phase 2, Phase 3]
Phase 2/3 trial comparing pyronaridine-artesunate to artemether-lumefantrine for malaria shows efficacy and safety data from completed study…
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CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy [Phase 3]
Phase 3 randomized trial evaluating three artemisinin-based combination therapies for malaria in pregnancy has completed.
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CLINICAL_TRIALS trial_result · 2022-03-14Clinical Trial Update: Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination [Phase 3]
Phase 3 trial evaluating mass drug administration of ivermectin and dihydroartemisinin-piperaquine as an additional intervention for malaria…
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CLINICAL_TRIALS trial_result · 2022-02-24Clinical Trial Update: Adjunctive Ivermectin Mass Drug Administration for Malaria Control [Phase 3]
Phase 3 clinical trial update on adjunctive ivermectin MDA for malaria control and related neglected tropical diseases.
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CLINICAL_TRIALS trial_result · 2022-02-18Clinical Trial Update: A Challenge Study to Assess the Safety, Immunogenicity and Efficacy of a Malaria Vaccine Candidate [Phase 1, Phase 2]
Phase 1/2 trial update evaluating a malaria vaccine candidate for safety, immunogenicity, and efficacy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo [Phase 4]
Phase 4 trial update assessing safety and efficacy of a recommended antimalarial in the Democratic Republic of the Congo has completed.
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CLINICAL_TRIALS trial_result · 2022-01-28Clinical Trial Update: Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) [Phase 3]
Phase 3 trial update on seasonal malaria vaccination (RTS,S/AS01) and seasonal malaria chemoprevention (SP/AQ) completed with results posted…
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CLINICAL_TRIALS trial_result · 2022-01-28Clinical Trial Update: Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali [Phase 1]
This Phase 1 trial assessed safety and immunogenicity of two malaria transmission-blocking vaccines, Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01,…
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria [Phase 3]
Phase 3 trial comparing pyronaridine artesunate to chloroquine in children and adults with acute vivax malaria; the study was terminated wit…
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: Human Mass Balance Study of Pyronaridine [Phase 1]
Phase 1 study evaluating human mass balance of pyronaridine in malaria patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali [Phase 2]
Phase 2 clinical trial evaluating gametocytocidal and transmission-blocking efficacy of PQ with AL and TQ with SPAQ in malaria patients in M…
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: Safety and Protective Efficacy of Pb(PfCS@UIS4) [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and protective efficacy of Pb(PfCS@UIS4); results completed with posted results in 2021.
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects [Phase 1]
Phase 1 trial assessing safety, tolerability, and pharmacokinetics of intravenous KAE609 in healthy subjects for malaria; study completed wi…
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CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria [Phase 2]
Phase 2 trial update for MMV390048 in Plasmodium vivax and Plasmodium falciparum malaria; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: Vectron T500 (Broflanilide 50WP) for IRS in Tanzania Tanzania [Phase 3]
Phase 3 clinical trial update for Vectron T500 (Broflanilide 50WP) investigating its use for indoor residual spraying against Falciparum mal…
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CLINICAL_TRIALS trial_result · 2021-11-22Clinical Trial Update: Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients [Phase 3]
Phase 3 trial comparing pyronaridine-artesunate 3:1 granules to crushed Coartem tablets in pediatric Plasmodium falciparum malaria; study co…
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CLINICAL_TRIALS trial_result · 2021-11-12Clinical Trial Update: Assessing a Risk Model for G6PD Deficiency [Phase 4]
Phase 4 trial assessing a risk model for glucose-6-phosphate dehydrogenase (G6PD) deficiency related to malaria; study terminated with resul…
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CLINICAL_TRIALS trial_result · 2021-10-13Clinical Trial Update: VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules [Phase 1, Phase 2]
A Phase 1/2 trial evaluating different dose schedules of R21/MM for malaria has been completed.
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CLINICAL_TRIALS trial_result · 2021-10-07Clinical Trial Update: Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children [Phase 2]
Phase 2 trial update assessing safety, tolerability, and protective efficacy of the PfSPZ Vaccine in Gabonese children for malaria.
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CLINICAL_TRIALS trial_result · 2021-09-20Clinical Trial Update: Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients [Phase 3]
Phase 3 trial comparing Pyronaridine Artesunate (3:1) to Coartem in Plasmodium falciparum malaria; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-09-20Clinical Trial Update: Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria [Phase 3]
Phase 3 trial update of Pyronaridine Artesunate (3:1) in children and adults with acute Plasmodium vivax malaria; study completed with resul…
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites [Phase 1]
Phase 1 clinical trial investigating blood-stage malaria infection after direct venous inoculation of cryopreserved Plasmodium falciparum NF…
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland [Phase 3]
Phase 3 trial update on reactive focal mass drug administration for malaria elimination conducted in Swaziland, completed.