Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: Comparing Chemoprevention Drugs for School-based Malaria Control [Phase 4]
A Phase 4 clinical trial comparing chemoprevention drugs for school-based malaria control has completed.
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: Chemoprevention Efficacy Study Nigeria [Phase 4]
Phase 4 clinical trial update focusing on malaria chemoprevention efficacy; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-08-03Clinical Trial Update: A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and Infants [Phase 1, Phase 2]
A multicenter early-phase trial evaluating safety and immunogenicity of a new malaria vaccine in Kenyan adults, children, and infants has co…
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate [Phase 1, Phase 2]
A crossover bioavailability study of parenteral pyronaridine and artesunate is being conducted in Phase 1 and Phase 2 for severe malaria tre…
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CLINICAL_TRIALS trial_result · 2023-07-18Clinical Trial Update: Safety and Efficacy of Maytenus Senegalensis for the Treatment of Uncomplicated Malaria [Phase 2]
Phase 2 trial update evaluating safety and efficacy of Maytenus senegalensis for uncomplicated malaria has completed.
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Blood-Stage Plasmodium Vivax Cell Bank [Phase 1]
Phase 1 clinical trial update for a Blood-Stage Plasmodium vivax cell bank; trial completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-26Clinical Trial Update: Gut and Azithromycin Mechanisms in Infants and Children II [Phase 4]
A Phase 4 clinical trial update on mechanisms of gut and azithromycin in infants and children for malaria, with completed status and posted …
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CLINICAL_TRIALS trial_result · 2023-06-13Clinical Trial Update: Effect of Paracetamol on Kidney Function in Severe Malaria [Phase 3]
Phase 3 trial investigating the effect of paracetamol on kidney function in patients with severe malaria.
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil [Phase 3]
Phase 3 trial comparing DHA-PQP versus chloroquine plus primaquine for radical cure of vivax malaria in Brazil has completed.
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: MSP3-CRM-Vac4All/ Alhydrogel® Vaccine [Phase 1, Phase 2]
Phase 1/2 clinical trial update for the MSP3-CRM-Vac4All/Alhydrogel vaccine addressing malaria caused by Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Trial to Evaluate CIS43LS in Healthy Adults [Phase 1]
Phase 1 trial evaluating CIS43LS in healthy adults for malaria has completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F [Phase 1]
Phase 1 trial update reporting safety, tolerability, pharmacokinetics, and pharmacodynamics of TB31F for malaria caused by Plasmodium falcip…
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: Seasonal Malaria Chemoprevention With Dihydroartemisin Piperaquin vs. Sulfadoxine-pyrimethamin+Amodiaquin [Phase 3]
Phase 3 trial update comparing dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine+amodiaquine for seasonal malaria chemoprevent…
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CLINICAL_TRIALS trial_result · 2023-02-24Clinical Trial Update: Single Low-dose Primaquine Efficacy and Safety. [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of a single low-dose primaquine for malaria.
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CLINICAL_TRIALS trial_result · 2023-02-23Clinical Trial Update: TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014
A completed clinical trial update investigating artemether-lumefantrine for Plasmodium falciparum and chloroquine for Plasmodium vivax malar…
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CLINICAL_TRIALS trial_result · 2023-02-03Clinical Trial Update: Pyronaridine Artesunate-Ritonavir Drug-drug Interaction Study [Phase 1]
Phase 1 trial update evaluating drug-drug interaction with pyronaridine artesunate-ritonavir for malaria; results posted.
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CLINICAL_TRIALS trial_result · 2023-02-03Clinical Trial Update: Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet [Phase 1]
Phase 1 bioequivalence trial comparing pyronaridine artesunate to the reference tablet for a to-be-marketed formulation; completed with resu…
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CLINICAL_TRIALS trial_result · 2023-01-06Clinical Trial Update: Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals [Phase 4]
Phase 4 trial update focused on optimizing malaria treatment in individuals co-infected with HIV.
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CLINICAL_TRIALS trial_result · 2022-11-15Clinical Trial Update: Comparing Chemoprevention Approaches for School-based Malaria Control [Phase 4]
Phase 4 trial update comparing chemoprevention approaches for school-based malaria control completed.
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Ivermectin-artemisinin Combination Therapy for Eradication of Malaria [Phase 4]
A Phase 4 clinical trial evaluating an ivermectin-artemisinin combination for malaria eradication is ongoing, with the status currently unkn…
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali [Phase 2]
Phase 2 trial of the Pfs230D1M-EPA/AS01 malaria transmission-blocking vaccine in Mali (children and family compound setting) has completed a…
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CLINICAL_TRIALS trial_result · 2022-07-15Clinical Trial Update: Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan [Phase 4]
Phase 4 cluster randomized trial evaluating malaria rapid diagnostic tests used by community health workers in Afghanistan has completed.
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... [Phase 1, Phase 2]
Phase I/II randomized trial evaluating PfSPZ-CVac malaria vaccination with pyrimethamine or chloroquine chemoprophylaxis; completed with pos…
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2) [Phase 2]
A Phase 2 clinical trial evaluating a single low dose tafenoquine to reduce transmission of Plasmodium falciparum malaria in Mali has comple…
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: Safety and Efficacy of NF135 CPS Immunization [NA]
Clinical trial update for NF135 CPS immunization shows termination with posted results, involving malaria falciparum and controlled human ma…