Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali [Phase 2]
A Phase 2 trial in Mali evaluating the gametocytocidal and transmission-blocking effects of ASAQ and ALAQ with or without primaquine in falc…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Improving Maternal heAlth by Reducing Malaria in African HIV Women [Phase 3]
A Phase 3 trial evaluating strategies to improve maternal health by reducing malaria in African HIV-infected pregnant women has completed.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire [Phase 3]
A Phase 3 clinical trial evaluating insecticide resistance management for malaria control in Burkina Faso and Côte d'Ivoire has completed.
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial evaluating KAF156 (ganaplacide) with Lumefantrine Solid Dispersion Formulation (LUM-SDF) in children with uncomplicated Plasmo…
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study [Phase 3]
Phase 3 extension study evaluating seasonal malaria vaccination RTS,S/AS01 with seasonal malaria chemoprevention SP/AQ in children has compl…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine
A completed surveillance study in African children evaluated adverse events of special interest and other events leading to hospitalization …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Improving Knowledge, Attitudes and Practices for Malaria Prevention in the Embera Katio Population [NA]
A completed clinical trial sponsored by Universidad de Antioquia evaluated strategies to improve knowledge, attitudes, and practices for mal…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Short Course Radical Cure of P. Vivax Malaria in Nepal [Phase 4]
This clinical trial update reports the completion of a Phase 4 study in Nepal evaluating a short-course radical cure for Plasmodium vivax ma…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Performance of an Ultrasensible Malaria Rapid Diagnostic Test Among Pregnant Women in Burkina Faso
This trial update reports on the performance of an ultrasensitive malaria rapid diagnostic test among pregnant women in Burkina Faso, using …
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Proactive Community Case Management for Malaria in Zambia [NA]
PATH-sponsored clinical trial on proactive community case management for malaria in Zambia has completed.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Studies of a Candidate Aminoquinoline Antimalarial (AQ-13) [Phase 2]
Phase 2 trials of AQ-13, a candidate aminoquinoline antimalarial, have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Anti-malaria MAb in Malian Children [Phase 2]
Phase 2 clinical trial of an anti-malaria monoclonal antibody in Malian children has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Efficacy of Only IV Artesunate Versus IV Artesunate Plus IV Quinine in the Treatment of Severe Malaria in Children: A Comparative Study [NA]
A completed comparative trial in children with severe malaria evaluates the efficacy of IV artesunate alone versus IV artesunate plus IV qui…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities [NA]
A completed clinical trial evaluating mass drug administration with dihydroartemisinin-piperaquine and a single low-dose primaquine to accel…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Evaluating ATSBs for Malaria Reduction in Kenya [NA]
This document reports the completion of a clinical trial evaluating Attractive Targeted Sugar Baits (ATSBs) for malaria reduction in Kenya.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: Controlled Human Malaria Infection Transmission Model - Phase A [Phase 1, Phase 2]
This update reports that the Phase A controlled human malaria infection transmission model trial (Phase 1/2) led by the University of Oxford…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age [Phase 2]
Phase 2 trial results update for GSK's malaria vaccine candidate SB257049, evaluating efficacy, safety and immunogenicity with schedules inc…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP [Phase 1]
Phase 1 study reports safety, tolerability, and antimalarial activity of single doses of OZ439 and PQP in malaria; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia [Phase 4]
Phase 4 trial update evaluating the efficacy of artesunate-amodiaquine and artemether-lumefantrine for treating uncomplicated Plasmodium fal…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Mali [Phase 1]
A Phase 1 study of the malaria transmission-blocking vaccine Pfs230D1-EPA/Matrix-M in adults in Mali has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria [NA]
This completed trial update reports results of TESTsmART Aim 2 in Nigeria, evaluating malaria diagnostic testing and conditional subsidies i…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali [Phase 2]
Phase 2 trial in Mali evaluating the safety and efficacy of CIS43LS, an anti-malaria monoclonal antibody, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Chemoprophylactic Activity of M5717 in PfSPZ Challenge Model [Phase 1]
Phase 1 trial update evaluating the chemoprophylactic activity of M5717 against malaria using the PfSPZ Challenge model in healthy volunteer…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar [NA]
This clinical trial update describes the efficacy of focal primaquine mass administration to eliminate Plasmodium vivax malaria in northern …
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays
This clinical investigation assesses the consistency and reproducibility of two consecutive mosquito feeding assays in malaria research; res…