Malaria
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Study to Assess the Vaccine Efficacy Against Malaria Infection, in Children Immunized With the Primary and Yearly Booster of the RTS,S/AS01E Vaccine, as Part of Their Participation in the Malaria-094 (204889/NCT03276962) Study.
This clinical trial update reports the completion and posted results of a study evaluating vaccine efficacy against malaria infection in chi…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates [Phase 4]
A Phase 4 clinical trial in Burkina Faso completed, evaluating simultaneous screening and treatment of roommates to enhance the effectivenes…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003) [Phase 1]
MK-7602-003 has completed a Phase 1 trial evaluating the safety and potential antimalarial activity of MK-7602 in healthy adults.
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Perennial Malaria Chemoprevention (PMC) in Cameroon
The document provides an update on the Cameroon trial of Perennial Malaria Chemoprevention (PMC). It indicates the study is currently ACTIVE…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Extended Duration Artemether-lumefantrine Treatment for Malaria in Children [Phase 4]
Phase 4 clinical trial update on extended-duration artemether-lumefantrine treatment for uncomplicated Plasmodium falciparum malaria in chil…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Malaria Vaccine Pilot Evaluation
A pilot evaluation of a malaria vaccine has completed, reporting feasibility and safety outcomes in relation to Plasmodium falciparum malari…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria [Phase 2]
Phase 2 trial evaluating the safety, tolerability, immunogenicity, and protective efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian adu…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults [Phase 1, Phase 2]
This clinical trial entry describes an adult malaria vaccine study comparing PfSPZ-CVac to MVA ME-TRAP and ChAd63 ME-TRAP across Phase 1 and…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: LAMP Detection of Malaria in PREGnancy (LAMPREG) Trial [NA]
The LAMPREG trial, evaluating LAMP-based detection of malaria in pregnancy, has completed enrollment with the study status shown as complete…
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: MMV533 Plasmodium Falciparum Volunteer Infection Study [Phase 1]
Phase 1 clinical trial update for MMV533 in a Plasmodium falciparum volunteer infection study; the study is completed and results have been …
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Cluster Randomized Trial of Peer Health Education in Malaria in The Gambia [Phase 3]
Phase 3 cluster-randomized trial assessing peer health education for malaria control in The Gambia has completed.
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Efficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets [NA]
Clinical trial results evaluating the efficacy of three novel bi-treated long-lasting insecticidal nets for malaria prevention.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI [Phase 1]
Phase 1 trial of PfSPZ Vaccine in healthy adults to evaluate safety, tolerability, and efficacy against heterologous controlled human malari…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Safety and Immunogenicity of RH5.1/Matrix-M in Adults and Infants Living in Tanzania [Phase 1]
Phase 1 trial evaluating safety and immunogenicity of the RH5.1/Matrix-M malaria vaccine in adults and infants in Tanzania; study completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania [Phase 4]
This Phase 4 trial update evaluates the implementation and effectiveness of intermittent preventive treatment for malaria in school-aged chi…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: LLIN Evaluation in Uganda Project [NA]
The LLIN Evaluation in Uganda Project has completed and posted results, evaluating long-lasting insecticidal nets for malaria prevention in …
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating two experimental malaria vaccines sponsored by the University of Oxf…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo [Phase 4]
Phase 4 trial completed evaluating the efficacy of the recommended antimalarial drugs for uncomplicated Plasmodium falciparum malaria in the…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Open-Label Study to Assess Meplazumab in Adult Patients Diagnosed with Plasmodium Falciparum [Phase 2]
An open-label, Phase 2 trial evaluating meplazumab in adults with Plasmodium falciparum malaria. The study is currently active but not recru…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Antimalarial Pharmacology in Children and Pregnant Women in Uganda
This update reports on a completed clinical trial evaluating antimalarial pharmacology in children and pregnant women in Uganda. The study i…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Community Dynamics of Malaria Transmission in Humans and Mosquitoes at Maferinyah Sub-Prefecture, Guinea
A completed clinical trial evaluated the community dynamics of malaria transmission in humans and mosquitoes in Maferinyah Sub-Prefecture, G…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Efficacy of Two Dual Active Ingredient Long Lasting Insecticidal Nets for Control of Malaria Transmitted by Pyrethroid Resistant Vectors in Benin [NA]
This clinical trial update reports on the efficacy of two dual active ingredient long-lasting insecticidal nets for reducing malaria transmi…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533. [Phase 1]
A Phase 1 study of MMV533 in malaria completed, assessing safety, tolerability, and pharmacokinetics after a single dose, with results poste…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Malaria as a Protection Factor Against Severe COVID-19 (Known as SARS-COV-2) in the Democratic Republic of Congo (Palu-COVID)
A terminated clinical trial in the Democratic Republic of Congo (Palu-COVID) evaluated whether malaria infection provides protection against…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Adaptive Interventions for Optimizing Malaria Control: a Cluster-Randomized SMART Trial [NA]
A completed cluster-randomized SMART trial evaluating adaptive interventions (LLIN, PBO-LLIN, IRS, and larviciding) for optimizing malaria c…