Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating safety, pharmacokinetics, and the transmission-reducing activity of the monoclonal antibody TB31F in …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women [NA]
This update reports the completion of a malaria mass drug administration trial assessing its effect on malaria prevalence in children under …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Clinical Prediction Models for Pediatric In-Hospital Death Risk in Congolese Severe Malaria Children Using Machine Learning Based-Algorithms
This completed clinical trial from the University of Kinshasa evaluates machine learning-based prediction models to estimate in-hospital mor…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: LLIN Evaluation in Uganda Project (LLINEUP3) [NA]
The LLIN Evaluation in Uganda Project (LLINEUP3) trial evaluating long-lasting insecticidal nets for malaria prevention in Uganda has comple…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: RTSS Vaccine and PBO Net Impact on Malaria Infection and Transmission in Malawi
This completed clinical trial in Malawi evaluated the impact of the RTS,S malaria vaccine (RTS,S/AS01) with insecticide-treated bed nets on …
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Vivax Elimination With Tafenoquine (VET) Study [Phase 4]
Phase 4 clinical trial update evaluating tafenoquine for eliminating Plasmodium vivax malaria; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria [Phase 4]
Phase 4 pharmacokinetic study evaluating intravenous artesunate in children with severe malaria has completed; the trial was sponsored by NI…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum [Phase 1]
Phase 1b PK/PD and safety data for MMV367 in experimentally induced blood-stage Plasmodium falciparum infection in healthy adults; the study…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults [Phase 1]
Phase 1 trial evaluated the safety and immunogenicity of PRIMVAC, a placental malaria vaccine candidate, in healthy adults and the study has…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults [Phase 1]
Phase 1 trial update of the Plasmodium vivax Pvs230D1-EPA/Matrix-M malaria vaccine in healthy malaria-naive adults. The study evaluated safe…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: FocaL Mass Drug Administration for Vivax Malaria Elimination [Phase 3]
Phase 3 clinical trial evaluating focal mass drug administration to eliminate Plasmodium vivax malaria; recruitment is ongoing, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda [Phase 3]
A Phase 3 trial in Uganda evaluating optimal chemopreventive regimens to prevent malaria and improve birth outcomes has completed and posted…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Anti-malaria MAb in Kenyan Children [Phase 2]
Phase 2 trial evaluating an anti-malaria monoclonal antibody in Kenyan children has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants [Phase 1]
Phase 1 single-ascending-dose trial assessing safety, tolerability, and pharmacokinetics of MMV371 LAI in healthy participants; study comple…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: L9LS MAb in Malian Infants [Phase 1]
Phase 1 trial update for the L9LS monoclonal antibody in Malian infants; the study investigating malaria prevention is active but not curren…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria [Phase 1]
Phase 1 trial of an investigational RNA-based malaria vaccine by BioNTech assessed safety and immune responses; study completed and results …
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon
This clinical trial update reports the completion of a study led by Karolinska Institutet that investigates the relationship between diabete…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique [Phase 4]
Phase 4 trial in Mozambique evaluating the in vivo efficacy of four ACT regimens for malaria.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
This clinical trial update reports the completion and results of a comparative study on thrombocytopenia in Plasmodium vivax malaria versus …
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Full Assessment of Clinical Transfusion Support
Clinical trial update noting the completion of a study on transfusion support in sickle cell anemia, with attention to malaria parasitaemia.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa [Phase 4]
GlaxoSmithKline completed a Phase 4 epidemiology study on malaria transmission intensity in Sub-Saharan Africa. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield [NA]
A completed clinical trial evaluating radical cure for vivax malaria among highly mobile and hard-to-reach populations in the Guyanese Shiel…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Optimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas [NA]
A completed University of Minnesota–sponsored clinical trial evaluating how to optimize the benefits and reduce risks of iron therapy in mal…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Permethrin-treated Baby-wraps for the Prevention of Malaria in Children [NA]
Completed clinical trial evaluating whether permethrin-treated baby wraps can prevent malaria in children.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso [Phase 1, Phase 2]
A completed Phase 1/2 trial in 5-17 month old children in Nanoro, Burkina Faso evaluated the safety, immunogenicity, and efficacy of the R21…