Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Evaluation of Seasonal Malaria Chemoprevention in Kita
A completed clinical trial in Kita evaluating Seasonal Malaria Chemoprevention (SMC), sponsored by the University of Bamako.
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia [Phase 2, Phase 3]
Phase 2/3 trial evaluating the safety of combining primaquine with dihydroartemisinin-piperaquine in G6PD-deficient males; the study was ter…
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Field Evaluation of Plant-based Mosquito Control [Phase 2]
Phase 2 field trial evaluating a plant-based mosquito control product has been completed, assessing its impact on malaria and arboviral infe…
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Bacillus Calmette-Guerin (BCG) Vaccine and Morbidity From Malaria [Phase 3]
A Phase 3 clinical trial evaluating whether the BCG vaccine affects malaria morbidity has completed.
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children [Phase 3]
Phase 3 trial assessing whether vitamin A with zinc and multivitamin supplementation reduces malaria morbidity in Ghanaian children; the stu…
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CLINICAL_TRIALS trial_result · 2016-08-10Clinical Trial Update: Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects [Phase 1]
Phase 1 trial evaluating ACT-451840 for early blood-stage Plasmodium falciparum infection in healthy subjects completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-08-08Clinical Trial Update: Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum [NA]
A completed clinical trial evaluating how host iron status and iron supplementation influence the erythrocytic stage of Plasmodium falciparu…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Malaria Prevention Cambodia [NA]
A clinical trial in Cambodia studying malaria prevention has terminated; the update provides no results.
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar
This clinical trial update reports completion of a molecular surveillance study of artemisinin resistance in Plasmodium falciparum malaria i…
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA) [Phase 1]
Phase 1 study (CHMI-SIKA) assessing controlled human malaria infection in semi-immune Kenyan adults; the trial status is currently unknown.
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Novel mHealth Platform to Ensure Quality of Community-based Malaria Diagnosis [NA]
This entry reports the completion of a clinical trial evaluating a mobile health platform designed to improve the quality of community-based…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria [NA]
This completed clinical trial assesses the impact of widescale sulfadoxine-pyrimethamine use on newborn outcomes in Nigeria, focusing on mal…
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Malaria Survey in the Tak Province Refugee Camps [NA]
This trial update notes the completion of a malaria survey conducted in refugee camps in Tak Province, sponsored by the University of Oxford…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults [Phase 1]
Phase 1 dose-escalation, randomized trial assessing safety, immunogenicity and efficacy of the PfSPZ Vaccine in Tanzanian adults; the study …
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo [Phase 4]
Phase 4 trial conducted in South Kivu, DR Congo evaluates the efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicat…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Hati Salama (Secure Voucher) [NA]
This update notes that the malaria-focused clinical trial Hati Salama has completed.
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Adults [Phase 1]
A Phase 1 study by Sanaria Inc. to optimize controlled human malaria infection using Plasmodium falciparum sporozoites in non-immune adults …
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults [Phase 1]
Phase 1 trial by Sanaria investigates controlled human malaria infection via intravenous Plasmodium falciparum sporozoites in non-immune adu…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT [NA]
This document reports the completion of a cluster randomized trial evaluating home-based child care to reduce mortality and malnutrition amo…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic
A completed clinical trial evaluating molecular markers of drug resistance in asymptomatic malaria cases and malaria antibody kinetics.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns [Phase 3]
A Phase 3 study evaluating cardiac safety with repeated doses of dihydroartemisinin-piperaquine for mass malaria treatment campaigns has com…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults [Phase 1]
Phase 1 study evaluating the safety and immunogenicity of direct venous inoculation of a radiation-attenuated PfSPZ vaccine in Equatoguinean…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana [Phase 3]
Phase 3 clinical trial update assessing the efficacy, safety, and tolerability of dihydroartemisinin-piperaquine for uncomplicated malaria i…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection [NA]
A completed clinical trial evaluating chemoprophylaxis during Plasmodium falciparum NF54 sporozoite immunization challenged by heterologous …
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: A Phase 1/2b Study of an Investigational Malaria Vaccination Strategy in 5-17 Month Old Infants and Children in Burkina Faso [Phase 1, Phase 2]
This is a completed Phase 1/2b trial evaluating an investigational malaria vaccination strategy in infants and children in Burkina Faso.