Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: Tafenoquine/Chloroquine DDI Study [Phase 1]
A Phase 1 study evaluating potential drug-drug interactions between tafenoquine and chloroquine in malaria has been completed.
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Tafenoquine Thorough QTc Study in Healthy Subjects [Phase 1]
Phase 1 thorough QTc study of tafenoquine in healthy subjects has been completed to assess potential effects on the QT interval.
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults [Phase 2]
Phase 2 clinical trial update evaluating safety, immunogenicity, and efficacy of a combined malaria vaccine in healthy malaria-naïve adults;…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) [Phase 1]
Phase 1 study evaluating the hemolysis risk of tafenoquine (TFQ) in relation to G6PD status. The trial has been completed.
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention [Phase 3]
A Phase 3 trial update evaluating the field efficacy of insecticide-treated uniforms and skin repellents for malaria prevention.
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: Computerized Cognitive Rehabilitation in Children After Severe Malaria [NA]
A clinical trial evaluating computerized cognitive rehabilitation in children after severe malaria has completed.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis [Phase 1]
Phase 1 trial evaluating immunity conferred by immunization with cryopreserved Plasmodium falciparum sporozoites under chloroquine prophylax…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis [Phase 1]
Phase 1 trial assessing safety and protective efficacy of intravenous immunization with cryopreserved Plasmodium falciparum sporozoites unde…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy [Phase 4]
Phase 4 trial update evaluating in vivo and in vitro efficacy of an artemisinin-based combination therapy for malaria.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands [NA]
This completed clinical trial conducted in the Solomon Islands studied seroprevalence and genetics related to flavivirus and alphavirus infe…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Phase Ia Study of ChAd63/MVA PvDBP [Phase 1]
A Phase Ia study of the ChAd63/MVA PvDBP vaccine for malaria caused by Plasmodium vivax has been completed.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children [Phase 2]
A Phase 2 double-blind study evaluated the safety and immunogenicity of two candidate malaria vaccines in Gabonese children; the trial has c…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Characterisation of the Immune Responses of 2 Experimental Malaria Vaccines [Phase 2]
Phase 2 trial update characterizes the immune responses to two experimental malaria vaccines developed by GlaxoSmithKline; the study status …
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection [Phase 2]
Phase 2 study evaluating the safety and protective efficacy of Bacillus Calmette-Guérin (BCG) vaccination against controlled human malaria i…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Surveillance of Effectiveness/Safety of Artemether-lumefantrine in Patients With Malaria
A completed study evaluating the effectiveness and safety of artemether-lumefantrine for malaria has reported its surveillance results. The …
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Safety and Efficacy Study of IV Artesunate to Treat Malaria [Phase 2]
A Phase 2 trial evaluating intravenous artesunate for malaria safety and efficacy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension [Phase 1]
Phase 1 single-dose study evaluating Atovaquone/Proguanil hydrochloride combination tablets and Atovaquone suspension for malaria; the trial…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Prevention of Malaria With Dihydroartemisinine + Piperaquine for Forest Rangers [Phase 4]
Phase 4 trial evaluating dihydroartemisinin plus piperaquine for malaria prevention in forest rangers has completed.
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: An Evaluation of Weekly Tafenoquine [Phase 2]
A Phase 2 trial evaluated weekly tafenoquine for falciparum parasitaemia (malaria) with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation [Phase 2]
Phase 2 trial OZ439 for Plasmodium falciparum malaria completed with extended observation. Results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Comparison of Two Strategies for the Delivery of IPTc [Phase 4]
Phase 4 trial comparing two strategies for delivering intermittent preventive treatment in children (IPTc) for malaria has completed.
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B [Phase 1, Phase 2]
This clinical trial update reports on MMV390048's antimalarial activity against Plasmodium falciparum in healthy adult subjects in a Phase 1…
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali [Phase 1, Phase 2]
A completed Phase 1/2 trial in Mali assessing the tolerable dose of primaquine in G6PD-deficient individuals without malaria.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers [Phase 1]
Phase 1 study update presents physiologically-based pharmacokinetic modeling of ivermectin in healthy volunteers to characterize its PK prof…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan [Phase 4]
The document reports the completion of a Phase 4 clinical trial assessing current standard malaria treatment guidelines in the Republic of t…