Malaria
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CLINICAL_TRIALS trial_result · 2017-08-18Clinical Trial Update: A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh [Phase 4]
Phase 4 clinical trial assessing safety of current standard malaria treatment and G6PD status in Southeast Bangladesh; study completed with …
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children [Phase 3]
A Phase 3 trial update reports consistency of immunogenicity and non-inferiority for GlaxoSmithKline's malaria vaccine lots in children.
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria [Phase 1]
A first-in-human Phase 1 study in healthy volunteers to investigate a new medicine for malaria conducted by GlaxoSmithKline has been termina…
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CLINICAL_TRIALS trial_result · 2017-07-31Clinical Trial Update: Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali [Phase 1]
A Phase 1 safety study of the malaria vaccine FMP1/AS02A in healthy adults in Mali has been completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali [Phase 1]
Phase 1 trial update for the malaria vaccine FMP2.1/AS02A in malaria-experienced adults in Mali; the study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region
This completed clinical trial assessed using Sysmex technology to differentiate malaria from bacterial infections in a malaria-endemic regio…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313 [Phase 1]
An update on a Phase 1 trial evaluating the safety and immunogenicity of two malaria vaccine candidates, ChAd63 Pfs25-IMX313 and MVA Pfs25-I…
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: Impact Evaluation of Community-Based Health Programs in Rwanda [NA]
A completed clinical trial in Rwanda evaluated community-based health programs addressing diarrhea and malaria.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase 1 Study of the Safety, Reactogenicity, and Immunogenicity of AMA1-C1/ISA 720: Blood Stage Vaccine for Plasmodium Falciparum [Phase 1]
Phase 1 study evaluating safety, reactogenicity, and immunogenicity of the AMA1-C1/ISA 720 blood-stage malaria vaccine; study completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Malaria Vaccine in Children in Mali [Phase 1, Phase 2]
The document reports the completion of Phase 1 and Phase 2 clinical trials of a malaria vaccine studied in children in Mali.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase I Study of AMA1-C1/Alhydrogel® (Registered Trademark) + CPG 7909 Malaria Vaccine [Phase 1]
Phase I study evaluating AMA1-C1/Alhydrogel with CpG 7909 as a malaria vaccine completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... [Phase 1]
Phase 1 trial evaluated the safety and protective efficacy of the Sanaria PfSPZ Challenge when given with pyrimethamine chemoprophylaxis to …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Phase I Study of Safety and Immunogenicity of AMA1-C1Alhydrogel + CPG 7909 Vaccine for Malaria [Phase 1]
A Phase I trial evaluating the safety and immunogenicity of the AMA1-C1 malaria vaccine formulated with Alhydrogel and CpG 7909; the study h…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Malaria Vaccine for Children in Mali [Phase 1]
A Phase 1 malaria vaccine trial in children in Mali has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Immune Parameters in the Cord Blood of Newborns Exposed to Malaria in the Womb
This entry describes a completed clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) examining imm…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Study of Factors Involved in Resistance to Severe Malaria
This clinical trial update reports a completed study investigating factors involved in resistance to severe malaria.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Examination of Protective Factors Against Severe Malaria
A completed clinical trial examining protective factors against severe malaria, sponsored by the National Institute of Allergy and Infectiou…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Improving the Efficacy of Experimental Malaria Vaccine AMA1-C1/Alhydrogel® (Registered Trademark) [Phase 1]
Phase 1 trial update on the malaria vaccine candidate AMA1-C1 formulated with Alhydrogel. The study status is completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Severe Malaria and Anti-malarial Drug Resistance in Cambodia
This clinical trial update from NIAID reports completed results related to severe malaria and antimalarial drug resistance in Cambodia.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Medical Implications of Coinfection With Malaria and Filariasis Parasites
A completed clinical trial update from NIAID examining the medical implications of coinfection with malaria and lymphatic filariasis.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Immune Response Regulation in People Infected Concurrently With Malarial and Filarial Parasites
A completed clinical trial by the National Institute of Allergy and Infectious Diseases examining immune response regulation in people co-in…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Estivation of Malaria Vector Mosquitoes in the Sahelian Region of Mali
A completed clinical trial sponsored by the National Institute of Allergy and Infectious Diseases investigated the estivation (seasonal dorm…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Malaria Incidence in Infants in Bancoumana, Mali
This entry reports a completed clinical trial studying malaria incidence and related anemia in infants in Bancoumana, Mali, sponsored by the…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Experimental Vaccine for Malaria [Phase 1]
This update notes the completion of a Phase 1 clinical trial evaluating an experimental malaria vaccine sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: A Study to Assess the Safety and Immunogenicity of a Malaria Vaccine Candidate, R21, Administered With AS01B [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of the malaria vaccine candidate R21 with AS01B has completed.