Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in Uganda
A completed clinical trial evaluated the impact of TMP-SMX prophylaxis on malaria infection and immunity in Ugandan children.
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CLINICAL_TRIALS trial_result · 2018-03-27Clinical Trial Update: "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania" [Phase 4]
A Phase 4 clinical trial conducted in Tanzania aims to prolong the therapeutic life span of artemisinin-based combination therapies for falc…
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax [Phase 2]
Phase 2 trial evaluating the protective efficacy of a vaccine derived from the synthetic circumsporozoite protein of Plasmodium vivax has be…
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: Immunization of Human Volunteers With P. Vivax Irradiated Sporozoites [Phase 1, Phase 2]
Phase 1/Phase 2 trial update of immunizing volunteers with Plasmodium vivax irradiated sporozoites for malaria.
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 [Phase 1, Phase 2]
This update reports the completion of Radboud University Medical Center's Study 1, a Phase 1/2 controlled human malaria infection model used…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Feasibility of the Vapor Nanobubble Technology for Malaria Diagnostics (MalariaSense) [NA]
A completed feasibility study evaluated Vapor Nanobubble Technology (MalariaSense) for malaria diagnostics.
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers [Phase 3]
Phase 3 trial evaluating primaquine's gametocytocidal efficacy in asymptomatic malaria carriers has completed.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Clinical Performance of the Histidine Rich Protein 2 (HRP2) Highly Sensitive Rapid Diagnostic Test (HS-RDT) for Malaria Diagnosis in Pregnant Women in Papua New Guinea
Clinical trial update evaluating the performance of the Histidine Rich Protein 2 Highly Sensitive Rapid Diagnostic Test for diagnosing malar…
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children [Phase 3]
Phase 3 trial update shows completion of testing for Seasonal Malaria Chemoprevention plus azithromycin in African children. The study evalu…
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CLINICAL_TRIALS trial_result · 2018-02-23Clinical Trial Update: Have Malaria Infections in Kenya Become Less Responsive to Artemisinin Treatment? [Phase 4]
Phase 4 trial update evaluating whether malaria infections in Kenya have become less responsive to artemisinin-based therapy; the trial stat…
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of two malaria vaccines in Ghanaian children.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Evaluating the Role of Chloroquine for Malaria Elimination [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluating the role of chloroquine for malaria elimination.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil [NA]
A completed clinical trial evaluating the efficacy of a treatment against malaria (Plasmodium vivax) conducted in Cruzeiro do Sul, Acre, Bra…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria [Phase 2]
Phase 2 clinical trial evaluating oral activated charcoal to assess its impact on the effectiveness of an antimalarial drug in Malian childr…
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi [Phase 3]
Phase 3 clinical trial update evaluating delivery of malaria chemoprevention in post-discharge management of children with severe anaemia in…
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot [Phase 4]
Phase 4 trial update comparing lumefantrine concentrations in venous plasma versus dried capillary blood spots for malaria.
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of artemisinin-based combination treatments for malaria conducted in the De…
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure [Phase 4]
Phase 4 clinical trial comparing artemether/lumefantrine vs dihydroartemisinin-piperaquine for uncomplicated malaria and evaluating parasite…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi [NA]
This completed trial evaluated whether sending text message reminders to health workers improves case management for malaria, pneumonia, and…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients [Phase 1]
Phase 1 clinical trial comparing mefloquine with sulfadoxine-pyrimethamine as malaria prophylaxis in pregnant HIV-positive patients has comp…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients [Phase 1]
Phase 1 clinical trial comparing azithromycin and sulfadoxine-pyrimethamine as malaria prophylaxis in HIV-positive pregnant women has comple…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women [Phase 3]
Phase 3 trial evaluating protease inhibitors to reduce malaria morbidity in HIV-infected pregnant women has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria [Phase 3]
Phase 3 study evaluating the efficacy and safety of pyronaridine-artesunate and artemether-lumefantrine in paediatric malaria; trial complet…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults [Phase 1]
Phase 1 trial evaluating safety and immunogenicity of the Plasmodium falciparum vaccine candidate FMP012 with AS01B in healthy malaria-naïve…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil [NA]
A clinical trial evaluating artemether-lumefantrine for treating Plasmodium falciparum malaria in Brazil has completed, with results posted …