Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers [Phase 1]
Phase I study of ascending doses of MMV390048 in healthy adults completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Study of the Safety of Intravenous Artesunate [Phase 1]
Phase 1 study assessing the safety of intravenous artesunate in malaria-related conditions, with completed status and results posted in 2018…
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults [Phase 2]
Phase 2 trial update on PfSPZ Vaccine exploring dose optimization with heterologous challenge in malaria-naïve adults completed.
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CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa [NA]
Clinical trial update on epidemiology of malaria transmission intensity completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: Novel Use Of Hydroxyurea in an African Region With Malaria [Phase 3]
Phase 3 trial assessing novel use of hydroxyurea in Africans with sickle cell disease; results completed and posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon [Phase 3]
Phase 3 clinical trial assessing artemisinin-based antimalarial combinations in Cameroon has completed.
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Evaluation of Weekly Tafenoquine [Phase 2]
Phase 2 clinical trial evaluating weekly tafenoquine for malaria has completed.
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum [Phase 2]
A phase 2 randomized, double-blind trial assessing increasing weekly doses of tafenoquine for chemosuppression of Plasmodium falciparum mala…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study [Phase 2]
Phase 2 trial evaluating efficacy and safety of high-dose ivermectin for reducing malaria transmission.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib [Phase 1]
This Phase Ia/Ib trial updates safety and immunogenicity data for the malaria blood-stage vaccine candidate P27A, with the study status show…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children [NA]
This clinical trial update describes the impact of preventive and therapeutic zinc supplementation programs among young children. The study …
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Testing Pfs25-EPA/Alhydrogel as a Potential Malaria Transmission Blocking Vaccine [Phase 1]
Phase 1 clinical trial evaluating Pfs25-EPA/Alhydrogel as a potential malaria transmission-blocking vaccine has completed. The study was spo…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Experimental PfSPZ Vaccine in Adults Without Malaria [Phase 1]
Phase 1 trial of the PfSPZ malaria vaccine in adults without malaria has completed, with the sponsor focusing on malaria prevention and immu…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: ELISA Validation of Hypersensitive Rapid Diagnostic Test Results for Detection of P. Falciparum
This completed study reports validation results for an ELISA-based hypersensitive rapid diagnostic test to detect Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children. [Phase 2]
A Phase 2 trial evaluated the efficacy of the RTS,S/AS01 malaria vaccine in children against episodes of malaria caused by Plasmodium falcip…
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses [Phase 1]
Phase 1 trial of the PfSPZ Vaccine in healthy malaria-naïve adults comparing heterologous vs homologous controlled human malaria infection a…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Cohort Event Monitoring in Sub Saharan Africa
A cohort event monitoring study conducted in Sub-Saharan Africa under the African Collaborating Centre for Pharmacovigilance has completed. …
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: Severe and Cerebral Malaria Investigated Through Host Metabolomics
A University of Oxford study investigating severe and cerebral malaria using host metabolomics has completed.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali
A completed clinical trial from Doneguebougou, Mali, assesses how antimalarial treatment affects measures of T cell suppression and regulati…
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria [NA]
A University of Oxford trial evaluated whether paracetamol affects oxidative stress and renal function in severe malaria; the study has comp…
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: A Safety and Efficacy Study of ChAdOx1 LS2 and MVA LS2 [Phase 1, Phase 2]
A safety and efficacy Phase 1/2 trial of malaria vaccine candidates ChAdOx1 LS2 and MVA LS2 by the University of Oxford has completed.
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP [Phase 1, Phase 2]
Update on safety and efficacy results from a phase 1/2 study of the malaria vaccines R21 with ChAd63/MVA ME-TRAP; the trial has completed.
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CLINICAL_TRIALS trial_result · 2018-05-15Clinical Trial Update: Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1 [Phase 1]
Phase 1 study investigating metabolism and pharmacokinetics of primaquine enantiomers in human volunteers related to malaria. The study is c…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Indonesia [NA]
A completed clinical trial evaluating spatial repellent products for malaria control in Indonesia.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia
The update reports Plasmodium falciparum clearance rates following artesunate treatment in eastern Cambodia. The study is sponsored by NIAID…