Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-09-30Clinical Trial Update: Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections [Phase 2]
Phase 2 trial update for Pyramax in asymptomatic carriers of Plasmodium falciparum monoinfections; status not disclosed.
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CLINICAL_TRIALS trial_result · 2019-09-26Clinical Trial Update: An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP [Phase 1, Phase 2]
An efficacy study of IV boosting with ChAd63/MVA ME-TRAP for malaria completed its Phase 1 and Phase 2 trials.
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. [Phase 3]
Phase 3 trial evaluating immunogenicity and safety of GSK's malaria vaccine given with routine vaccines at 6, 7.5, and 9 months, followed by…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetics study of oral formulations of MMV390048 in healthy volunteers completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: An Extension to Study MALARIA-055 PRI (NCT00866619) to Evaluate the Long-term Efficacy, Safety and Immunogenicity of GSK Biologicals' Candidate Malaria Vaccine in Infants and Children in Africa [Phase 3]
Phase 3 trial extension evaluating long-term efficacy, safety, and immunogenicity of GlaxoSmithKline's malaria vaccine in infants and childr…
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CLINICAL_TRIALS trial_result · 2019-08-01Clinical Trial Update: A FIH Study to Investigate the Safety, Tolerability and PK of P218 [Phase 1]
Phase 1 trial update for a first-in-human study evaluating safety, tolerability, and pharmacokinetics of P218 in malaria.
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Malaria Vaccine Safety and Immunogenicity Study in Healthy Adults [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of a malaria vaccine in healthy adults completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults [Phase 2]
Phase 2 trial assessing efficacy, immunogenicity, and safety of different dose schedules for GSK's malaria vaccine in malaria-naïve adults; …
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Cohort Event Monitoring Study of Pyramax® [Phase 4]
Phase 4 cohort event monitoring study of Pyramax for malaria caused by Plasmodium falciparum has completed.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults [Phase 1, Phase 2]
Clinical trial update for a malaria vaccine study (VMP001 with AS01B adjuvant) in healthy adults shows completed Phase 1/2 with posted resul…
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating the PfSPZ vaccine for safety, tolerability, and efficacy in healthy children and infants aged 5 month…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI) [Phase 4]
A Phase 4 randomized controlled trial evaluating primaquine treatment for uncomplicated malaria in Timika, Indonesia has completed.
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Spirulina Supplementation and Infant Growth, Morbidity and Motor Development [NA]
Completed clinical trial evaluating spirulina supplementation and its effects on infant growth, morbidity, and motor development.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: The Effectiveness of Non-Pyrethroid Insecticide-Treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania [Phase 3]
Phase 3 trial evaluating non-pyrethroid insecticide-treated durable wall liners for malaria control in rural Tanzania was terminated.
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected [Phase 1, Phase 2]
Phase 1/2 trial comparing protease inhibitor–based ART to a non-nucleoside reverse transcriptase inhibitor–based ART for clearance of Plasmo…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Sequential Optimization of Dose and Schedule of PfSPZ Vaccine [Phase 1]
Phase 1 trial completed to evaluate sequential optimization of dose and schedule for the PfSPZ Vaccine in malaria. The study aimed to identi…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Time to Infection With Malaria Parasites
This clinical trial update summarizes a completed study on the time to infection with Plasmodium falciparum malaria parasites.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Plasmodium Resistance in A. Gambiae
Completed clinical trial update examining Plasmodium resistance in Anopheles gambiae in the context of malaria (Plasmodium falciparum).
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: PfSPZ Challenge in Non-immune Adults in Baltimore, USA [Phase 1]
Phase 1 clinical trial of PfSPZ Challenge in non-immune adults in Baltimore has completed.
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CLINICAL_TRIALS trial_result · 2019-01-16Clinical Trial Update: Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children [Phase 3]
Phase 3 trial assessing safety and immunogenicity of GSK's investigational malaria vaccine in HIV-infected infants and children completed wi…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study [Phase 2, Phase 3]
Pilot safety and efficacy study evaluating repeat mass drug administrations of ivermectin for malaria control, completed with results posted…
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CLINICAL_TRIALS trial_result · 2018-12-28Clinical Trial Update: HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children [Phase 3]
Phase 3 trial evaluating HIV protease inhibitors for prevention of malaria in Ugandan children has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults [Phase 2]
Phase 2 trial assessing efficacy, safety, and immunogenicity of a GlaxoSmithKline malaria vaccine candidate in healthy malaria-naïve adults;…
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
Phase I/II clinical trial update for a malaria vaccine in adults in the United States (completed; results posted).
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants [Phase 3]
Phase 3 trial results evaluating strategies to reduce malaria burden in HIV-uninfected pregnant women and their infants were posted. The stu…