Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria. [Phase 2]
Phase 2 trial assessing safety of KAE609 in adults with uncomplicated Plasmodium falciparum malaria has completed and results posted.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria [Phase 3]
Phase 3 trial evaluating tafenoquine co-administered with dihydroartemisinin-piperaquine for radical cure of Plasmodium vivax malaria has co…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Dose Escalation PfSPZ-CVac [Phase 1]
Phase 1 dose-escalation trial of PfSPZ-CVac for malaria has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: Targeted Indoor Residual Spraying Against Malaria [Phase 4]
Phase 4 clinical trial update on targeted indoor residual spraying for malaria; study completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia [Phase 3]
Phase 3 trial evaluating reactive focal mass drug administration with or without reactive focal vector control for malaria in Namibia has co…
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A [Phase 1]
Phase 1 trial update on ascending oral doses of MMV390048 focusing on safety, tolerability, and pharmacokinetics in malaria patients; result…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Longitudinal Antimalarial Combinations in Uganda [Phase 3]
Phase 3 clinical trial update on longitudinal antimalarial combinations conducted in Uganda, completed.
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants [Phase 1]
Phase 1 trial evaluating MMV390048 for early blood-stage infection of Falciparum malaria in healthy participants; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01B [Phase 1]
Phase 1 trial evaluating safety and efficacy of FMP010 malaria protein with AS01B adjuvant completed with posted results in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection [Phase 1, Phase 2]
Phase 1/2 trial evaluating single-dose DSM265 or OZ439 for antimalarial activity and transmission-blocking in healthy subjects with induced …
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent [Phase 1, Phase 2]
Phase 1/2 trial update evaluating OZ439 as a gametocytocidal and transmission-blocking agent for malaria; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Experimental Falciparum Transmission to Anopheles [Phase 1]
Phase 1 trial update on an experimental intervention addressing transmission of malaria to Anopheles mosquitoes; study completed with posted…
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CLINICAL_TRIALS trial_result · 2020-05-15Clinical Trial Update: A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults [Phase 2]
Phase 2 clinical trial evaluating a fractional booster dose of GlaxoSmithKline's malaria vaccine in previously vaccinated malaria-naïve adul…
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CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III) [Phase 4]
Phase 4 trial update evaluating in vivo efficacy of artemether-lumefantrine and amodiaquine-artesunate for malaria in Mozambican children ha…
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 [NA]
A completed clinical trial evaluating transmission-blocking interventions using a controlled human malaria infection model in malaria falcip…
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: Methylene Blue Against Falciparum Malaria in Burkina Faso [Phase 2]
Phase 2 trial evaluating methylene blue for falciparum malaria completed in Burkina Faso with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas [Phase 3]
Phase 3 trial updating hydroxyurea therapy in children with sickle cell disease in malaria-endemic areas has completed.
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection [Phase 2]
Phase 2 clinical trial evaluating artemisinin-based combination therapies for schistosomiasis with malaria co-infection; study status comple…
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Effect of Paracetamol on Renal Function in Plasmodium Knowlesi Malaria [Phase 3]
Phase 3 trial assessing the effect of paracetamol on renal function in patients with malaria (Plasmodium knowlesi).
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study [Phase 1]
Phase 1 study examining pharmacokinetics of OZ439 with different dose volumes and cobicistat co-administration for malaria.
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1 [Phase 1]
Phase 1 trial update evaluating safety and immunogenicity of the malaria vaccine R21 with and without Matrix-M1.
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CLINICAL_TRIALS trial_result · 2019-11-06Clinical Trial Update: A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant [Phase 1, Phase 2]
A clinical trial update for the malaria vaccine R21 with Matrix-M1 adjuvant across Phase 1 and Phase 2 evaluating safety and immunogenicity;…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2) [NA]
Clinical trial update on a public-private partnership related to subsidized antimalarials in the retail sector; study status completed with …
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CLINICAL_TRIALS trial_result · 2019-10-28Clinical Trial Update: Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria Vaccine [Phase 1, Phase 2]
Phase 1/2a trial of a Plasmodium falciparum GAP p52/p36 sporozoite malaria vaccine was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-09Clinical Trial Update: Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa [Phase 3]
Phase 3 trial update for GSK's malaria vaccine candidate 257049 in infants and children in Africa; results posted after completion.