Malaria
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: DON in Pediatric Cerebral Malaria [Phase 1, Phase 2]
This entry notes an ongoing Phase 1/Phase 2 clinical trial evaluating DON for pediatric cerebral malaria, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Monoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital Discharge [Phase 3]
Phase 3 clinical trial evaluating monoclonal antibodies to prevent malaria after hospital discharge in children with severe anaemia or sever…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Post-discharge Malaria Chemoprevention Implementation Trial in Benin [Phase 4]
A Phase 4 post-discharge malaria chemoprevention trial in Benin is currently recruiting to evaluate strategies for preventing malaria after …
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) [NA]
A clinical trial is investigating whether L-Arginine can prevent adverse pregnancy outcomes and is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Clinical Practices for Treating Severe Malaria Caused by P. Falciparum
This document provides an update on clinical practices for treating severe malaria caused by Plasmodium falciparum, based on completed trial…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Star Homes Project 2 [NA]
University of Oxford is conducting Star Homes Project 2 and currently recruiting participants for malaria, acute respiratory tract infection…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy [Phase 3]
This clinical trial update describes a Phase 3 study evaluating sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine for intermitte…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: EaveTubes for Vector Control [NA]
The University of Notre Dame is updating a clinical trial for the EaveTubes vector-control intervention targeting malaria, with the study cu…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia [Phase 3]
PATH-sponsored Phase 3 clinical trial in Ethiopia evaluating targeted antimalarial drug administration for seasonal migrant populations in t…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Evaluation of IR3535 as a Spatial Repellent for Malaria Control. [NA]
This clinical trial update concerns evaluating IR3535 as a spatial repellent for malaria control. The study is currently active but not recr…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth [Phase 3]
Phase 3 clinical trial evaluating gestational sulfadoxine-pyrimethamine and azithromycin to prevent preterm birth; the study is active but n…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite With the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAP [Phase 1]
Phase 1 clinical trial update for experimental malaria infection in healthy malaria-naive adults using genetically modified Plasmodium falci…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso. [Phase 1, Phase 2]
A Phase 1/2 clinical trial in Burkina Faso is evaluating an experimental blood-stage malaria vaccine; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine
A clinical trial update indicating ongoing recruitment in Ghana for the RTS,S/AS01 malaria vaccine to strengthen policy evidence.
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Trajectories and Mechanisms of Recovery From Malaria: An Observational Study
An observational study conducted by Imperial College London examining how patients recover from malaria, including trajectories and underlyi…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Host Immunity, Plasmodium and Pathogens Co-Infections [NA]
Clinical trial from Institut Pasteur studying host immunity in Plasmodium infection and bacterial co-infections; not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Perennial Malaria Chemoprevention (PMC) in Côte D'Ivoire
The Perennial Malaria Chemoprevention trial in Côte d'Ivoire is listed as ACTIVE_NOT_RECRUITING, sponsored by the London School of Hygiene a…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial [Phase 2, Phase 3]
Recruitment is ongoing for a Phase 2/3 randomized trial evaluating a triple artemisinin-based combination therapy aimed at delaying drug res…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Evaluation of Artesunate in Infants Being Treated for Severe Malaria
This clinical trial is evaluating artesunate in infants with severe malaria and is currently recruiting.
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: A Study to Compare Two Dosing Regimens for a New Malaria Vaccine [Phase 1]
Phase 1 study comparing two dosing regimens for a new malaria vaccine to assess safety and preliminary immunogenicity.
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, and pharmacokinetics of different orally administered regimens of the ZY19489-Ferroq…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Diagnostic Access to Self-Care and Health Services in Low and Middle Income Countries (DASH) - Phase II [NA]
This DASH Phase II trial assesses diagnostic access to self-care and health services in low- and middle-income countries, with focus areas i…
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: Seasonal R21 Mass Vaccination for Malaria Elimination [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate the seasonal R21 malaria vaccine for malaria elimination. The study is sponsored by the L…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Malaria Molecular Surveillance in Mozambique (Phase 2)
Phase 2 malaria molecular surveillance trial in Mozambique is currently recruiting.
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Evaluation of a Comprehensive School Health Programme in Zambia [NA]
Status update on an ongoing trial in Zambia evaluating a comprehensive school health programme targeting helminth infections, malaria and re…