Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: NMDA Modulation in Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial evaluating NMDA receptor modulation as treatment for Major Depressive Disorder is currently recruiting at China Med…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Trazodone on NREM Sleep Stage Ⅲ in Depressed Insomniac Co-morbid Patients [Phase 4]
Phase 4 clinical trial evaluating trazodone's effect on NREM sleep stage III in patients with comorbid depression and insomnia; recruitment …
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Impact of Psychomotor Therapy on the Quality of Life in Depression [NA]
A clinical trial evaluating whether psychomotor therapy improves quality of life for adults with major depressive disorder is currently recr…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Social Stress and Suicide [NA]
A clinical trial examining the effects of social stress on suicide risk in individuals with a history of major depressive episodes has compl…
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FDA approval · 2025-02-18FDA Approved: ARIPIPRAZOLE — Supplemental Application (Bionpharma Inc.)
FDA approved a supplemental application from Bionpharma Inc. for aripiprazole (generic), enabling its continued commercialization with the a…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects [NA]
Clinical trial evaluating the EDIT-B blood test in patients with bipolar disorder or major depressive disorder, assessing its impact on heal…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Snack Foods and Their Impact on Mental Health and the Gut-brain Axis [NA]
A completed clinical trial from King's College London examining whether snack foods influence depression, anxiety, and the gut-brain axis.
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Evolution of the Sensory Profile in Depression
A clinical trial investigating the evolution of the sensory profile in major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD) [Phase 2]
A Phase 2 trial evaluating TNX-601 ER as monotherapy versus placebo in adults with major depressive disorder has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature [NA]
Completed clinical trial evaluating the NeuroStar SoftStart Treatment Feature for Major Depressive Disorder; results have been posted.
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Game-Based Digital Intervention for Depression in Adolescents [NA]
This entry reports a clinical trial update for a game-based digital intervention aimed at treating depression and anxiety in adolescents, wi…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Consultation-Liaison Intervention for Patients with Depression and Anxiety in Primary Care [NA]
This completed clinical trial from the University of Zurich evaluated a consultation-liaison intervention for patients with depression and a…
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FDA approval · 2025-02-15FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (XLCare Pharmaceuticals, Inc.)
The FDA approved a supplemental application for Sertraline Hydrochloride from XLCare Pharmaceuticals, Inc., authorizing the generic product.
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FDA approval · 2025-02-14FDA Approved: ARIPIPRAZOLE — Supplemental Application (Bionpharma Inc.)
FDA approved a supplemental application for aripiprazole from Bionpharma Inc., enabling the generic product to be marketed in the United Sta…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline
Clinical trial evaluating tamoxifen in women with breast cancer and in women at high risk who are taking certain antidepressants or gabapent…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression [Phase 3]
Phase 3 clinical trial investigating Ammoxetine Hydrochloride Enteric-coated Tablets for major depressive disorder is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Implementation Science Approach to Enhancing Depression Treatment in Collaborative Depression Care Settings ( DepCare ) [NA]
The clinical trial update reports a completed study (DepCare) that tests an implementation science approach to enhancing depression treatmen…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: The Efficacy and Safety of Task-state-based Temporal Interference Stimulation (TI) in the Treatment of Patients With Depression [NA]
This update describes a planned clinical trial evaluating Task-state-based Temporal Interference Stimulation for Major Depressive Disorder, …
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Ketamine As an Adjunctive Therapy for Major Depression (2) [Phase 3]
A Phase 3 study evaluating ketamine as an adjunctive therapy for major depressive disorder has completed.
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Stepped Care Model of Lifestyle-based Mental Health Care for Depression [NA]
This clinical trial update describes a stepped care model of lifestyle-based mental health care for depression, sponsored by the Chinese Uni…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Veteran's Perceptions of Ketamine-Assisted Psychotherapy for Depression and End-of-Life
A ClinicalTrials.gov update indicates a study evaluating ketamine-assisted psychotherapy for depression in veterans is currently recruiting.…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Beyond Efficacy- Eliciting Preference for Face-to-face and Internet-based Psychotherapy Among People with Depression
A completed clinical trial update examining preferences for face-to-face versus internet-based psychotherapy among people with depression.
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Efficacy of Mindfulness-cognitive Oriented Group Intervention Program on Depressed University Students [NA]
A completed clinical trial evaluated the efficacy of a mindfulness-cognitive oriented group intervention for depression among university stu…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Investigating the Impacts of Early Life Experience on the Brain & Behaviour
The University of Manchester reports an ongoing recruiting study investigating how early life experiences influence brain and behavior relat…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Ketogenic Diet for Treatment-Resistant Depression: Dietary Interventions for MEntal Health Study (DIME) [NA]
The DIME study from the University of Oxford evaluating a ketogenic diet for treatment-resistant depression has completed; no efficacy resul…