Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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FDA approval · 2025-02-11FDA Approved: PAROXETINE — Supplemental Application (Padagis US LLC)
FDA approved a supplemental application for paroxetine (Padagis US LLC), updating the labeling to reflect expanded indications for the antid…
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FDA approval · 2025-02-11FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Lupin Pharmaceuticals, Inc.)
The FDA approved a supplemental application to authorize Lupin Pharmaceuticals' generic Bupropion Hydrochloride XL.
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: MonPsy&Moi: A Digital Platform for Collecting Patient-Reported Experience and Outcome Measures in Psychiatry
Clinical trial update describing MonPsy&Moi, a digital platform to collect patient-reported experiences and outcomes in psychiatry, sponsore…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: You Are What You Eat: Food As a Risk Factor and a Treatment for Depression [NA]
This completed University of Michigan clinical trial investigates whether diet influences depression risk and whether dietary interventions …
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Early Intervention Coping Kids (TIM) Follow up Study [NA]
This clinical trial update covers the University of Oslo's TIM Follow-up Study, a pediatric trial on coping interventions for anxiety disord…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Implementation of Internet-based Psychotherapy for Symptoms of Depression, Insomnia and Anxiety in Primary Care in the Cities of Indaiatuba and Jaguariuna [NA]
Clinical trial update on implementing internet-based psychotherapy for depression, insomnia, and anxiety in primary care in Indaiatuba and J…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset [NA]
A clinical trial evaluating NeuroStar TMS Therapy for major depressive disorder with postpartum onset was terminated, with results subsequen…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: ICBT and IEMDR-FT for Mental Health in Breast Cancer Patients [NA]
This completed trial examined internet-based cognitive behavioral therapy (ICBT) and internet-based EMDR-FT for mental health in breast canc…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Optimization of ITBS for Depression [NA]
This clinical trial is evaluating optimization of ITBS for depression and is currently recruiting at Université de Sherbrooke. It involves a…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial [Phase 1]
This update reports the completion of a Phase 1 pilot trial investigating AMPA receptor components in the antidepressant response to ketamin…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response [Phase 1]
A Phase 1 clinical trial at Yale University is recruiting to investigate AMPA receptor components involved in the antidepressant response to…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: The Community Youth Development Study: A Test of Communities That Care [NA]
This clinical trial update reports on The Community Youth Development Study, a community-based evaluation of the Communities That Care progr…
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CLINICAL_TRIALS withdrawal · 2025-02-07Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of REL-1017 As Adjunctive Treatment of Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 study evaluating REL-1017 as an adjunctive treatment for major depressive disorder has been withdrawn. The sponsor is MGGM LLC.
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Effects of a Virtual Reality Intervention on Mental Health Outcomes and Academic Success in Physical Therapy Students [NA]
Ongoing clinical trial evaluating a virtual reality intervention to affect mental health outcomes and academic success among physical therap…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Inflammation and Depression Following SCI [NA]
This clinical trial is evaluating transcutaneous auricular vagus nerve stimulation (taVNS) to reduce inflammation and depression in people w…
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CLINICAL_TRIALS withdrawal · 2025-02-06Clinical Trial Update: Clinical Investigation of Syndi [NA]
The clinical investigation of Syndi, sponsored by Newcastle University, has been withdrawn; the trial targeted depression and anxiety-relate…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults with SCI [NA]
Clinical trial update on a home-based action observation and motor imagery intervention for cognitive function and depression in adults with…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: TACS on High-inflammatory and Refractory Depression [NA]
A clinical trial is evaluating transcranial alternating current stimulation (TACS) for patients with treatment-resistant depression and infl…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Healthy Expectations - a Program for Pregnant Women Experiencing Depressive Symptoms [NA]
The Healthy Expectations trial, a program for pregnant women experiencing depressive symptoms, has completed.
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination [NA]
This clinical trial update reports completed results for a study exploring personalized effects of affective bias modification on symptoms a…
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CLINICAL_TRIALS withdrawal · 2025-02-05Clinical Trial Update: Immediate Effects of DLPFC tDCS on Attention Bias [NA]
A Johns Hopkins University-sponsored trial evaluating the immediate effects of dorsolateral prefrontal cortex transcranial direct current st…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: RTMS Feasibility Study on Adolescent Depression Stimulation [NA]
A completed feasibility study evaluating repetitive transcranial magnetic stimulation (RTMS) for adolescent depression.
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: A Systems-Level Intervention for Rural Adults With Depression [NA]
University of Michigan completed a systems-level intervention trial for rural adults with depressive symptoms; results have been posted.
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Baby Swim As an Intervention for Depressive Symptoms and Lacking Attachment During the Postpartum Period [NA]
This clinical trial is evaluating Baby Swim as an intervention for depressive symptoms and attachment issues in the postpartum period. The s…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: rTMS for MDD: 5.5cm Rule vs. F3 Targeting [NA]
Completed study comparing 5.5 cm rule versus F3 targeting for repetitive transcranial magnetic stimulation (rTMS) in major depressive disord…