Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: Ketamine Alcohol (in Treatment-Resistant Depression) [Phase 2]
A Phase 2 trial evaluating ketamine in treatment-resistant depression with comorbid alcohol use is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: In Vivo Cortical Excitability Modulation in Major Depressive Disorder
A clinical trial funded by Fundação Champalimaud is evaluating in vivo cortical excitability modulation for Major Depressive Disorder. The s…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Preventing Postpartum Depression With Intranasal Oxytocin [Phase 2]
Phase 2 trial evaluating intranasal oxytocin to prevent postpartum depression has completed, with results posted. The study also collected d…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions [Phase 1]
A Phase 1 study sponsored by Boehringer Ingelheim evaluating BI 1358894 in adults with major depressive disorder to examine effects on brain…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Managing Cancer and Living Meaningfully (CALM) Therapy in Individuals Diagnosed With a Primary Brain Tumor [NA]
Completed clinical trial evaluating CALM therapy for individuals with a primary brain tumor who have depression; results have been posted. T…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Acceptance and Commitment Therapy for Depressed Individuals Living With Spinal Cord Injury Sustained Within 5 Years [NA]
A completed clinical trial evaluating Acceptance and Commitment Therapy for depression in individuals with spinal cord injury within five ye…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: The Association Between Physical Symptoms and Depression Among Medical Students in Egypt
A Cairo University–sponsored clinical trial completed in Egypt investigates the association between physical symptoms and depression among m…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression [NA]
A clinical trial is investigating whether extended cannabis abstinence improves symptoms and cognition in adults with major depressive disor…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Internet-based Support for Adjustment to Prostate Cancer [NA]
An internet-based support program to help patients adjust to prostate cancer is being studied in a clinical trial. The study targets outcome…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD) [Phase 2]
Phase 2 clinical trial evaluating lemborexant for residual insomnia in adults with major depressive disorder; the study is not yet recruitin…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Conversations With Caregivers About Health and Appearance [NA]
A University of Oregon-led clinical study is recruiting participants to explore conversations with caregivers about health and appearance, f…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Opiate Suicide Study in Patients With Major Depression [Phase 3]
This is an update on a Phase 3 clinical trial examining an opiate-related intervention for major depressive disorder, with status listed as …
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: 7T Amygdala and Citalopram Study [NA]
This entry notes an ongoing University of Oxford study using 7T amygdala imaging to investigate the effects of citalopram on emotional proce…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury [NA]
Updates on a clinical trial evaluating intermittent fasting to address inflammation and depression in people with spinal cord injury. The st…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Community Intervention to Improve Depressive Symptoms Among Older Adults (VIDACTIVA) [NA]
This clinical trial update reports the completion of a community-based intervention (VIDACTIVA) aimed at reducing depressive symptoms among …
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women [NA]
Clinical trial completion and results posted for a mindfulness-based intervention targeting post-traumatic stress disorder and depressive sy…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Stress and Pain in People Living With HIV [NA]
Yale University is conducting a clinical trial on stress and pain in people living with HIV, including depression and cannabis use disorder,…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Precision Transcranial Magnetic Stimulation for Depression Based on Orbital Frontal Cortex-habenula Circuitry [NA]
This clinical trial update describes a precision transcranial magnetic stimulation study for depression targeting the orbital frontal cortex…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression [NA]
This clinical trial update describes a study on attentional biases toward affective cues in infants of mothers with depression; the trial is…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications [NA]
A completed clinical trial tested a mobile app–based cognitive behavioral therapy plus real-time pain management for people with sickle cell…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: NMDA Modulation in Antidepressant Nonresponders With Major Depressive Disorder [Phase 2]
Phase 2 clinical trial evaluating NMDA modulation in antidepressant nonresponders with major depressive disorder is currently recruiting. Th…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Single Ascending Dose Study of NH102 in Healthy Subjects [Phase 1]
Phase 1 single ascending dose study of NH102 conducted in healthy subjects has completed. The trial focused on safety, with Depression liste…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: ELE-101 Safety & Tolerability Study in Healthy Participants and Patients With Depression [Phase 1, Phase 2]
Overview of ELE-101 safety and tolerability evaluated in healthy volunteers and individuals with Major Depressive Disorder in Phase 1/2, cur…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Potency and Precision Investigation [NA]
A completed clinical trial sponsored by Woebot Health evaluating potency and precision, with results posted on 2025-02-19, focusing on depre…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Pharmacogenomics on Individualized Precise Treatment of Patients With Depression [NA]
Completed clinical trial update on pharmacogenomics-guided, individualized treatment for depression conducted by Tongji University.