Major Depressive Disorder
📧 Sign up to get email alerts when something new happens for Major Depressive Disorder.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND) [Phase 2]
A Phase 2 clinical trial investigating psilocybin for treatment-resistant depression and chronic pain is currently recruiting.
-
CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Does Psilocybin Require Psychedelic Effects to Treat Depression? [Phase 2]
A Phase 2 clinical trial is exploring whether psilocybin's psychedelic effects are necessary to treat treatment-resistant depression, and th…
-
CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Post-Stroke Optimization of Walking Using Explosive Resistance [Phase 2]
Phase 2 trial evaluating explosive-resistance training to improve walking after stroke; results were posted in April 2025.
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Leucine in Midlife Depression [Phase 2]
A Phase 2 trial from Emory University is evaluating leucine for midlife depression and is currently recruiting.
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD [Phase 2]
A Phase 2 dose-finding trial is evaluating the efficacy and safety of LV232 capsules for major depressive disorder. The study is currently r…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Youth Depression and Suicide Research Network
This update indicates that the Youth Depression and Suicide Research Network is currently enrolling by invitation to study depression and su…
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Sensory Synchronized Imaging and Neuromodulation [NA]
A new clinical trial investigating sensory synchronized imaging and neuromodulation for major depressive disorder is currently recruiting.
-
CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Temporal Interference and Depression [NA]
This clinical trial update shows that a study on Temporal Interference for Major depressive disorder is currently recruiting. The phase is n…
-
CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: LSD Therapy for Persons Suffering From Major Depression [Phase 2]
A Phase 2 clinical trial evaluating LSD-based therapy for major depressive disorder has completed.
-
FDA approval · 2025-04-23FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA approved a supplemental application for venlafaxine hydrochloride submitted by Macleods Pharmaceuticals Limited.
-
CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: A Study to Evaluate Efficacy and Safety of GW117 Tablets in Major Depressive Disorder [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of GW117 tablets for major depressive disorder has completed.
-
CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Disentangling Pharmacological and Expectation Effects in Antidepressant Discontinuation [NA]
Clinical trial update examining pharmacological versus expectation effects in antidepressant discontinuation, sponsored by Universitätsklini…
-
CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Effects of an ACT-based Psychological Treatment in Patients With Chronic Kidney Disease [NA]
This entry describes a recruiting clinical trial evaluating Acceptance and Commitment Therapy-based psychological treatment for patients wit…
-
CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Maintenance rTMS for Depression (Maitr-De) [NA]
Clinical trial update for maintenance rTMS in depression shows a recruiting study for major depressive disorder and treatment-resistant depr…
-
CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Neuroinflammation in COVID-19 and Depression
A clinical trial investigating neuroinflammation in patients with COVID-19 and major depressive disorder has completed.
-
CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Microglial Activation in Inflammatory Bowel Disease
This clinical trial update reports on microglial activation in inflammatory bowel disease and its relation to major depressive episodes, wit…
-
CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Evaluating the Feasibility of a School-based Stepped Care Program for Internalizing Symptoms in Adolescents in Pakistan [NA]
A feasibility study evaluating a school-based stepped care program to address internalizing symptoms (depression and anxiety) among adolesce…
-
CLINICAL_TRIALS research · 2025-04-21Clinical Trial Update: Brain Connectivity in Depression [NA]
This clinical trial update indicates that Brigham and Women's Hospital is recruiting participants for a study on brain connectivity in depre…
-
CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine [EARLY_Phase 1]
Emory University is conducting an early-phase 1 trial to explore whether glutamatergic adaptation to stress underpins anhedonia and treatmen…
-
CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: The Mindfulness-Based Psycho-Educational Program Focused on Emotion Regulation Strategies [NA]
Clinical trial update for a mindfulness-based psycho-educational program focused on emotion regulation; the study is active but not recruiti…
-
FDA approval · 2025-04-18FDA Approved: BUPROPION HYDROCHLORIDE SR — Supplemental Application (Dr. Reddys Laboratories Inc.)
FDA approved a supplemental application for Bupropion Hydrochloride SR from Dr. Reddy's Laboratories, authorizing its continued marketing as…
-
CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Effect of Tao Calligraphy Meditation and Energized Water on Depression [NA]
A clinical trial is evaluating Tao Calligraphy Meditation and Energized Water for unipolar depression, and is currently recruiting.
-
CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Psychological Effect of Explicit Recall After Sedation (PEERS)
The PEERS trial (NCT04747379) examining the psychological effect of explicit recall after sedation has completed. The study addresses awaren…
-
CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: From Fear to Purpose ACT Protocol. Implications of Death Anxiety in Depression and Anxiety Symptoms. [NA]
This clinical trial protocol from Babes-Bolyai University investigates the role of death anxiety in depression and anxiety symptoms and prop…
-
CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Pramipexole to Enhance Social Connections [Phase 2]
A Phase 2 trial is evaluating pramipexole to enhance social connections in individuals with anxiety disorders and depression; the study is c…