Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: The Lived Experiences Measured Using Rings Pilot Study [Phase 2]
The University of Vermont-conducted Phase 2 pilot study on lived experiences related to depression, stress, sleep, and anxiety has completed…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Effect of ChatGPT-Based Digital Counseling on Anxiety and Depression in Cancer: A Randomized Trial [NA]
A completed randomized trial evaluated the effect of ChatGPT-based digital counseling on anxiety and depression in cancer patients.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers [EARLY_Phase 1]
A Phase 1 study of Ketamine-assisted Psychotherapy for existential distress in patients with non-operable gastrointestinal cancers was termi…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: The Danish Neuropsychological Study of the Adverse Effects of ECT
Clinical trial update from the University of Copenhagen examining adverse effects of electroconvulsive therapy in depressive disorders.
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder [NA]
This clinical trial update indicates recruitment for an individualized non-invasive brain stimulation approach using transcranial alternatin…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Living Well: A Digital ACT Intervention [NA]
Complete update on a clinical trial of Living Well, a digital ACT intervention. The study targeted depressive symptoms and anxiety.
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CLINICAL_TRIALS withdrawal · 2025-04-16Clinical Trial Update: Humanoid Robot vs Treatment as Usual for Loneliness [NA]
A trial comparing a humanoid robot intervention to treatment as usual for loneliness and depression has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program [NA]
This clinical trial update notes ongoing recruitment for a program aimed at improving identity and coping skills to address chronic stress, …
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Income Volatility and Mental Health, Pilot Study [NA]
Pilot study results examining the relationship between income volatility and depressive symptoms have been completed and results posted.
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EMA approval · 2025-04-15EMA Authorised: Valdoxan (agomelatine) — Les Laboratoires Servier
The EMA authorised Valdoxan (agomelatine) for major depressive disorder, with Les Laboratoires Servier as the marketing authorisation holder…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Mobile Transcranial Magnetic Stimulation [NA]
A completed clinical trial evaluating mobile transcranial magnetic stimulation for depression, sponsored by the University of Regensburg.
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Metacognitive Therapy for Depression and Generalized Anxiety Disorder in Primary Care, Blended Version of Mediated Treatment [NA]
Update on a primary care trial of metacognitive therapy for depression and generalized anxiety disorder, using a blended mediated-treatment …
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: The Utility of Concurrent TBS/fNIRS for Antidepressant Treatment Optimization [NA]
A completed clinical trial evaluating concurrent TBS and fNIRS for optimizing antidepressant treatment in Major Depressive Disorder.
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: A Neuroimaging Study of Open-label Placebo in Depressed Adolescents [NA]
This entry reports a neuroimaging study of open-label placebo in depressed adolescents, sponsored by the University of California, San Franc…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
An ongoing Mayo Clinic study recruiting participants to identify cerebral hemodynamic patterns in mood disorders and mild cognitive impairme…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Investigating Dynamic Interactions in Distributed Cognitive Control Networks
Clinical trial update on an ongoing study at the University of Alabama at Birmingham examining dynamic interactions in distributed cognitive…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings [NA]
Completed clinical trial of the Friendship Bench mental health intervention for adolescent girls and young women in South Africa within PrEP…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial [NA]
A multicenter randomized trial evaluating primary care behavioral health with added self-help CBT is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
A clinical trial update shows recruitment for a study examining how benzodiazepines affect cognitive function using fNIRs and PET/MRI at The…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression [NA]
This clinical trial update reports on the clinical effectiveness of the TARA therapy versus standard treatment for depression in adolescents…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Imaging SV2A in Mood Disorders [NA]
This clinical trial update indicates ongoing recruitment for a study using SV2A imaging to investigate mood disorders, specifically major de…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression [NA]
A clinical trial studying modulation of repetitive negative thinking brain networks in young adults with major depressive disorder has been …
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Increasing Psychological Resilience in Combat Soldiers Applying Advanced Eye-Tracking-Based Attention Bias Modification [NA]
Tel Aviv University completed a trial evaluating an eye-tracking-based attention bias modification designed to increase psychological resili…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Understanding and Treating Suicidal Ideation With Ketamine [Phase 2, Phase 3]
A clinical trial update indicates ketamine is being studied in Phase 2 and Phase 3 trials for suicidal ideation and major depressive disorde…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder [Phase 1, Phase 2]
Phase 1/2 clinical trial updates show results for using ketamine to rapidly treat Major Depressive Disorder and Alcohol Use Disorder, with c…