Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Neurocognitive Enhancement in Major Depressive Disorder [NA]
The clinical trial investigating neurocognitive enhancement in Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Concurrent Treatment for Depressed Parents and DepressedAdolescents [NA]
A completed clinical trial from Brown University studied concurrent treatment for depressed parents and depressed adolescents; results were …
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression [Phase 4]
A Phase 4 trial examining continuation electroconvulsive therapy for relapse prevention in major depression has been terminated.
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FDA approval · 2015-08-28FDA Approved: ESCITALOPRAM — Original Application (SOLCO HEALTHCARE US, LLC)
The FDA approved an original application for a generic escitalopram product from Solco Healthcare US, LLC, for the treatment of major depres…
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FDA approval · 2015-08-27FDA Approved: MIRTAZAPINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for a generic mirtazapine product from Mylan Pharmaceuticals Inc., confirming continued approval of …
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FDA approval · 2015-08-26FDA Approved: DULOXETINE — Original Application (Ascend Laboratories, LLC)
The FDA approved Ascend Laboratories' original application for a generic duloxetine product (ANDA 203197), establishing a generic version of…
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CLINICAL_TRIALS research · 2015-08-24Clinical Trial Update: Prevalence Study of Depression in Chinese Patients With Type 2 Diabetes (HK13)
This completed observational study assessed how prevalent depression is among Chinese patients with type 2 diabetes.
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FDA approval · 2015-08-21FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for quetiapine fumarate from Aurobindo Pharma Limited, providing a generic version of the antips…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Desipramine for Improving Cellular Signaling and Decreasing Symptoms of Major Depression [Phase 4]
This document reports a Phase 4 clinical trial evaluating desipramine for improving cellular signaling and reducing symptoms in major depres…
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FDA approval · 2015-08-14FDA Approved: ARIPIPRAZOLE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal's original ANDA for aripiprazole (ARIPIPRAZOLE), enabling the marketing of a generic version of this antipsychotic.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Ostrobothnia Depression Study (ODS). A Naturalistic Follow-up Study on Depression and Related Substance Use Disorders [NA]
This completed naturalistic follow-up study investigated depression and related substance use disorders. It did not evaluate a specific drug…
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: Assessing the Impact of Self-directed Care, Within a Medicaid-funded Environment,on Participation and Community Living [NA]
Completed clinical trial update evaluating the impact of self-directed care in a Medicaid-funded environment on participation and community …
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: Assessing Anterior Cingulate Brain Activity in People With Late-Life Depression
This clinical trial studying anterior cingulate brain activity in people with late-life depression has completed.
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CLINICAL_TRIALS research · 2015-08-11Clinical Trial Update: A Genotype Stratification Study for Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Male Subjects [Phase 1]
This Phase 1 clinical trial investigates how genetic differences influence the pharmacokinetics and pharmacodynamics of amitriptyline in hea…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: The Brain on Whole Body Hyperthermia: A Neuroimaging Study [NA]
A University of Arizona study investigating whole body hyperthermia with neuroimaging in adults with major depressive disorder has completed…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: Whole Body Hyperthermia and Major Depression (MDD) [NA]
The clinical trial evaluating whole-body hyperthermia for major depressive disorder has completed. The study was sponsored by the University…
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CLINICAL_TRIALS withdrawal · 2015-08-07Clinical Trial Update: Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder [Phase 2]
The Phase 2 trial evaluating the effects of Seroquel XR on sleep architecture in Major Depressive Disorder has been withdrawn.
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CLINICAL_TRIALS research · 2015-08-04Clinical Trial Update: e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions [NA]
This clinical trial update discusses the e-Pharmacovigilance II program focused on safety and effectiveness monitoring and calls for earlier…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Chicago Urban Resiliency Building (CURB) [NA]
The CURB trial (Chicago Urban Resiliency Building) for major depression has completed.
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Lexapro for Major Depression in Patients With Epilepsy [Phase 4]
A Phase 4 trial evaluating Lexapro (escitalopram) for major depressive disorder in patients with epilepsy was terminated, with results poste…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Family Based Treatment of Depressed Adolescents [Phase 2]
A Phase 2 clinical trial evaluating family-based treatment for depressed adolescents has been terminated.
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: Nefazodone in the Treatment of Cocaine Dependence and Depression - 4 [Phase 2]
Phase 2 clinical trial of nefazodone for cocaine dependence with comorbid depression has completed (sponsor: Boston Medical Center).
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: Prevalence and Risk Factors in Unipolar Depression Patients Without Remission After One Antidepressant Trial
AstraZeneca-sponsored study completed, assessing the prevalence and risk factors in patients with major depressive disorder who did not remi…
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury [Phase 3]
Phase 3 trial evaluating dietary interventions for reducing chronic inflammation and related disorders after spinal cord injury has complete…
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Depression-Diabetes Mechanisms: Urban African Americans [Phase 4]
A Phase 4 clinical trial investigating mechanisms linking depression and diabetes in urban African American adults has completed. Results we…