Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Enhancing Psychotherapy for Mood Disorders With Whole Body Hyperthermia [NA]
A clinical trial evaluating whole-body hyperthermia as an adjunctive treatment for major depressive disorder has been terminated. The sponso…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Blame Rebalance fMRI Feedback Proof-of-concept [NA]
A completed clinical trial evaluating a proof-of-concept fMRI feedback approach for major depressive disorder.
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Depression, Epinephrine, and Platelet Function [Phase 4]
Phase 4 clinical trial update examining the relationship between depression, epinephrine, and platelet function; results were posted in 2015…
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CLINICAL_TRIALS withdrawal · 2015-07-21Clinical Trial Update: Mood and Anti-craving Effects of Varenicline in Psychiatric Inpatients [NA]
The clinical trial evaluating mood and anti-craving effects of varenicline in psychiatric inpatients was withdrawn.
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CLINICAL_TRIALS trial_result · 2015-07-16Clinical Trial Update: Deep Brain Stimulation in Treatment Refractory Depression [Phase 1, Phase 2]
The trial update reports termination of a Phase 1/2 study evaluating deep brain stimulation for treatment-refractory major depressive disord…
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FDA approval · 2015-07-15FDA Approved: NORTRIPTYLINE HYDROCHLORIDE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
The FDA approved a supplemental application for Nortriptyline Hydrochloride from Dr. Reddy's Laboratories Inc.
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CLINICAL_TRIALS trial_result · 2015-07-15Clinical Trial Update: Randomized-controlled Trial of Aftercare-Coordination by Phone for Depression and Anxiety [NA]
This document reports that the randomized-controlled trial evaluating aftercare coordination by phone for depression and anxiety has complet…
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CLINICAL_TRIALS trial_result · 2015-07-15Clinical Trial Update: Modeling and Predicting Real World Behavior Using Mobile Sensor Data on Patients With Major Depressive Disorder [NA]
This completion notice describes a study by Ginger.io that used mobile sensor data to model and predict real-world behavior in patients with…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder [Phase 3]
A Phase 3 trial evaluating synchronized transcranial magnetic stimulation (sTMS) for major depressive disorder has completed, with results p…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Trial of Telephone-based Psychotherapy for Depression With and Without Adjunctive Supportive Mail [NA]
The study reports results for telephone-based psychotherapy for depression, with and without adjunctive supportive mail, and its status is l…
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CLINICAL_TRIALS trial_result · 2015-07-13Clinical Trial Update: Cluster Randomized Trial of Stepped Care Intervention vs. Treatment as Usual for Patients With Depression [NA]
This entry notes the completion of a cluster randomized trial comparing a stepped care intervention to treatment as usual for patients with …
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CLINICAL_TRIALS trial_result · 2015-07-13Clinical Trial Update: Mindfulness Meditation Format Pilot Study [Phase 1]
Phase 1 pilot study evaluating a mindfulness meditation format for posttraumatic stress disorder and depression has been completed. The tria…
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Electroconvulsive Therapy (ECT) for Elderly Patients With Major Depression [Phase 4]
An update on a Phase 4 clinical trial evaluating electroconvulsive therapy for elderly patients with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Treatment of Suicidal Ideation With Intravenous Ketamine Infusion [NA]
A completed clinical trial evaluated intravenous ketamine infusion for suicidal ideation in depression, with results posted in 2015.
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CLINICAL_TRIALS research · 2015-07-08Clinical Trial Update: A Prospective Epidemiological Research on Functioning Outcomes Related to Major Depressive Disorder
A completed prospective epidemiological study evaluating functioning outcomes in individuals with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: An Expert System to Reduce Depression in Primary Care [Phase 2]
Phase 2 trial update of an expert system aimed at reducing depression in primary care; results posted after completion.
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Liothyronine (T3) for Bipolar Depression [Phase 3]
Phase 3 trial evaluating Liothyronine (T3) for bipolar depression has completed with results posted in 2015. The sponsor is Northwell Health…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: The Effect on Depressive Symptoms in ECF Residents With COPD [Phase 4]
Phase 4 clinical trial update assessing the effect on depressive symptoms in residents with chronic obstructive pulmonary disease; results p…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: Preventing Depression Relapse With Mindfulness-Based Cognitive Therapy [Phase 4]
A Phase 4 clinical trial update reports a completed study evaluating mindfulness-based cognitive therapy to prevent relapse in depression. T…
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CLINICAL_TRIALS trial_result · 2015-06-30Clinical Trial Update: The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression [Phase 2]
Phase 2 trial evaluating whether adding minocycline impacts relapse after an initial ketamine/minocycline response in major depressive disor…
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FDA approval · 2015-06-29FDA Approved: DESVENLAFAXINE — Original Application (Advagen Pharma Ltd)
FDA approved Advagen Pharma Ltd's original application for desvenlafaxine (generic), enabling a generic version of the antidepressant.
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CLINICAL_TRIALS trial_result · 2015-06-29Clinical Trial Update: Creatine as a Treatment Option for Depression in Methamphetamine Using Females [Phase 4]
A Phase 4 trial evaluated creatine as a treatment for depression in females using methamphetamine, and results were posted in 2015.
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FDA approval · 2015-06-29FDA Approved: DESVENLAFAXINE SUCCINATE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' generic desvenlafaxine succinate in an Original Application (ANDA 204172) for the treatment of major dep…
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FDA approval · 2015-06-29FDA Approved: DESVENLAFAXINE — Original Application (Alembic Pharmaceuticals Limited)
FDA approves Alembic Pharmaceuticals' original application for desvenlafaxine succinate (desvenlafaxine) as a generic antidepressant.
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Treatment of Comorbid Depression and Substance Abuse in Young People [Phase 2]
Phase 2 clinical trial investigating treatment for comorbid depression and substance use disorders in youth has completed enrollment. The up…