Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: The Efficacy, Safety, and Tolerability of Probiotics on the Mood and Cognition of Depressed Patients [Phase 3]
Phase 3 clinical trial evaluating probiotics for mood and cognition in patients with major depressive disorder; study completed.
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: Improving Mood in Veterans in Primary Care [NA]
Clinical trial on improving mood in veterans in primary care has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-13Clinical Trial Update: Vortioxetine vs Sertraline in Mexicans [Phase 4]
Phase 4 trial comparing vortioxetine to sertraline in Mexican patients with depression and type 2 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2019-06-12Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression [Phase 2]
Phase 2 trial update showing safety and efficacy results for intranasal esketamine in treatment-resistant depression, with results posted in…
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CLINICAL_TRIALS trial_result · 2019-06-11Clinical Trial Update: An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder [Phase 2]
Phase 2 study evaluating the efficacy and safety of sirukumab in adults with major depressive disorder; the trial has completed and results …
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: PCORI-1306-02918 Evaluation of Parent-based Programs to Support Children After Traumatic Injury [NA]
A completed clinical trial evaluating parent-based programs to support children after traumatic injury; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: Nurse-Led Interprofessional Mental Health Promotion Intervention for Older Home Care Clients
Clinical trial evaluating a nurse-led interprofessional mental health promotion intervention for older home care clients with depressive sym…
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CLINICAL_TRIALS trial_result · 2019-06-06Clinical Trial Update: Ketamine for Suicidality in Bipolar Depression [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating ketamine for suicidality in bipolar depression; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-06Clinical Trial Update: the Efficacy and Safety of Agomelatine in the Patients With Parkinson's Disease [Phase 4]
Phase 4 trial evaluating the efficacy and safety of agomelatine in patients with Parkinson's disease and depression.
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CLINICAL_TRIALS trial_result · 2019-06-04Clinical Trial Update: Buprenorphine Used With Treatment Resistant Depression in Older Adults [Phase 1, Phase 2]
Clinical trial updates on buprenorphine for treatment resistant depression in older adults have completed phases 1 and 2 with posted results…
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: IntelliCare Study: Artificial Intelligence in a Mobile (AIM) Intervention for Depression [NA]
Clinical trial update for the AIM intervention using artificial intelligence to treat depression and anxiety; study completed with results p…
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology [NA]
Clinical trial assessing the effects of buprenorphine on mood in adults with depressive symptoms has completed with results posted.
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FDA approval · 2019-05-23FDA Approved: FLUOXETINE — Original Application (Cadila Pharmaceuticals Limited)
Cadila Pharmaceuticals Limited received FDA approval for an original application of fluoxetine (generic).
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FDA approval · 2019-05-22FDA Approved: DULOXETINE — Supplemental Application (Zydus Lifesciences Limited)
FDA approves a supplemental application for a generic duloxetine from Zydus Lifesciences Limited, authorizing marketing of the product.
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: A Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD) [Phase 2]
Phase 2 clinical trial evaluating ALKS 5461 for major depressive disorder has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: Daily Weight Feedback for Wheelchair Users to Promote Weight Loss [NA]
A completed clinical trial studying daily weight feedback for wheelchair users to promote weight loss in overweight individuals, with result…
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CLINICAL_TRIALS trial_result · 2019-05-20Clinical Trial Update: The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression [Phase 4]
Phase 4 clinical trial assessing safety and efficacy of naltrexone and scopolamine in treatment of major depression has completed with poste…
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CLINICAL_TRIALS trial_result · 2019-05-16Clinical Trial Update: Sevoflurane in Electroconvulsive Therapy [Phase 4]
Phase 4 clinical trial updating sevoflurane use in electroconvulsive therapy has been completed.
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Dichotic Listening as a Predictor of Medication Response in Depression [Phase 1, Phase 2]
A Phase 1/2 clinical trial explored dichotic listening as a predictor of medication response in depression, with results posted after comple…
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FDA approval · 2019-05-09FDA Approved: SPRAVATO — Supplemental Application (Janssen Pharmaceuticals Inc.)
The FDA approved a supplemental application for SPRAVATO (esketamine hydrochloride) submitted by Janssen Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2019-05-08Clinical Trial Update: African American Depression Intervention Trial (AADI) [Phase 3]
Phase 3 clinical trial update for the African American Depression Intervention Trial (AADI) investigating major depressive disorder.
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CLINICAL_TRIALS trial_result · 2019-05-08Clinical Trial Update: Role of Magnesium Supplementation in the Treatment of Depression [Phase 2, Phase 3]
A clinical trial update reports completed results for magnesium supplementation in treatment of depression across Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2019-05-08Clinical Trial Update: Behavioral Study of Effects of Low-Level Light Therapy on Mood and Reaction Time [NA]
A completed clinical trial evaluating the effects of low-level light therapy on mood and reaction time in individuals with depression; resul…
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FDA approval · 2019-05-07FDA Approved: DESVENLAFAXINE — Original Application (Marlex Pharmaceuticals, Inc.)
FDA approved Marlex Pharmaceuticals’ generic desvenlafaxine via an original ANDA submission. This establishes a generic option for the antid…
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression [Phase 3]
A Phase 3 long-term safety and efficacy study of intranasal esketamine for treatment-resistant depression has completed, with results posted…