Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Trial of Levomilnacipran in Geriatric Depression [Phase 4]
Phase 4 trial update for levomilnacipran in geriatric depression has completed with results posted.
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CLINICAL_TRIALS research · 2019-04-25Clinical Trial Update: Investigation of Genetic Predictors of the Response to Selective Serotonin Re-uptake Inhibitors (SSRI) Treatment [Phase 4]
A Phase 4 clinical trial evaluating genetic predictors of response to SSRI treatment in major depression.
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CLINICAL_TRIALS trial_result · 2019-04-24Clinical Trial Update: A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide [Phase 2]
Phase 2 double-blind study evaluating intranasal esketamine for rapid reduction of depressive symptoms and suicidal ideation in adults with …
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CLINICAL_TRIALS trial_result · 2019-04-24Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression [Phase 3]
Phase 3 study evaluated intranasal esketamine plus an oral antidepressant in elderly patients with treatment-resistant depression; results w…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Brain Mechanisms of Human Motivation
Completed clinical trial investigating brain mechanisms of human motivation in Major Depressive Disorder and Bipolar Disorder; results poste…
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression [Phase 3]
Phase 3 study evaluating the efficacy, safety, and tolerability of flexible doses of intranasal esketamine in combination with an oral antid…
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CLINICAL_TRIALS trial_result · 2019-04-19Clinical Trial Update: Effects of Therapist Behavior on the Treatment of Depressed Adolescents [Phase 1, Phase 2]
A completed phase 1/2 clinical trial evaluating how therapist behavior influences treatment outcomes in depressed adolescents.
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CLINICAL_TRIALS withdrawal · 2019-04-18Clinical Trial Update: A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults [Phase 4]
Phase 4 trial comparing medication augmentation versus PST for depression in older adults was withdrawn.
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FDA approval · 2019-04-17FDA Approved: DULOXETINE — Original Application (Qingdao BAHEAL Pharmaceutical Co., Ltd.)
FDA approved a generic version of duloxetine from Qingdao BAHEAL Pharmaceutical Co., Ltd. under an Original Application (ANDA 210599). The a…
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FDA approval · 2019-04-16FDA Approved: DESIPRAMINE HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals NY LLC)
FDA approved Amneal Pharmaceuticals NY LLC's supplemental application for desipramine hydrochloride, approving a generic version of desipram…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Study to Treat Major Depressive Disorder (MDD) With a New Medication [Phase 2]
A Phase 2 clinical trial evaluating a new medication for Major Depressive Disorder has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Implementing Health Plan-Level Care Management for Solo & Small Practices [NA]
Clinical trial update on care management implementation for solo and small practices in bipolar disorder and depression; study completed wit…
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FDA approval · 2019-04-16FDA Approved: DESIPRAMINE HYDROCHLORIDE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
FDA approved a supplemental application for desipramine hydrochloride from Heritage Pharmaceuticals (Avet) to support a marketed generic pro…
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FDA approval · 2019-04-15FDA Approved: FLUOXETINE HYDROCHLORIDE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approves Lupin's original (generic) application for fluoxetine hydrochloride.
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Evaluation of Depression Symptoms and Brain Activity Associated With Response to Treatment of Depression [Phase 4]
Phase 4 clinical trial evaluating how depression symptoms relate to treatment response and associated brain activity; results were posted in…
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CLINICAL_TRIALS trial_result · 2019-04-09Clinical Trial Update: Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder [Phase 4]
A Phase 4 trial update on adjunctive aripiprazole (Abilify) for inadequate response in major depressive disorder.
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CLINICAL_TRIALS research · 2019-04-09Clinical Trial Update: Psychological and Psychosocial Intervention With War-Affected Children [NA]
A completed clinical trial evaluating psychological and psychosocial interventions for war-affected children; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: Ketamine for Depression: An MRI Study [Phase 4]
Phase 4 clinical trial update on ketamine for depression, including anxious depression, with results posted.
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CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: Citalopram Titration in Early Non-responder Patients With Major Depressive Disorders [Phase 2]
Phase 2 clinical trial updating citalopram titration in early non-responders with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2019-04-01Clinical Trial Update: Predictors of Depression Treatment Response to Exercise [Phase 3]
Phase 3 clinical trial evaluating predictors of response to exercise treatment in Depression/Major Depressive Disorder has completed.
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FDA approval · 2019-03-29FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for Venlafaxine Hydrochloride from Sun Pharmaceutical Industries to support the generic product's co…
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CLINICAL_TRIALS trial_result · 2019-03-29Clinical Trial Update: Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients [NA]
Pilot study evaluating the health effects of daylight exposure in dementia patients; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-27Clinical Trial Update: A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - FORWARD-5 Study [Phase 3]
A Phase 3 clinical trial update for ALKS 5461 in treatment of Major Depressive Disorder has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-27Clinical Trial Update: A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-4 Study [Phase 3]
Phase 3 study update for ALKS 5461 in major depressive disorder completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-03-27Clinical Trial Update: A Study of Different Titration Schedules of ALKS 5461 in Adults With Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial update evaluating different titration schedules of ALKS 5461 in adults with Major Depressive Disorder has completed with resul…