Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2019-08-12Clinical Trial Update: Text Messaging and Cognitive Behavioral Therapy for Depression [NA]
A completed clinical trial investigating text messaging and cognitive behavioral therapy for depression with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-12Clinical Trial Update: Growth Mindset Psychoeducation for Modifiable Risk Factors for CMD [NA]
A completed clinical trial evaluating growth mindset psychoeducation for modifiable risk factors in depression and anxiety; results posted i…
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Modafinil's Effects on Cognition in Remitted MDD [Phase 3]
Phase 3 trial investigating modafinil for cognitive impairment in remitted major depressive disorder was terminated.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: Circadian Effects of Escitalopram [NA]
Clinical trial update on the circadian effects of escitalopram in depression; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: Omega-3 for Depression and Other Cardiac Risk Factors - 2 [Phase 2]
Phase 2 clinical trial update evaluating Omega-3 for depression and cardiac risk factors; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression [Phase 3]
Phase 3 clinical trial evaluating minocycline and celecoxib as adjunctive treatments for bipolar depression has completed.
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Medications for the Treatment of Dysthymic Disorder and Double Depression [Phase 4]
Phase 4 clinical trial update on medications for treating dysthymic disorder and double depression.
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND} [Phase 3]
A Phase 3 trial comparing sertraline to cognitive behavioral therapy for depression in patients with end-stage renal disease has completed w…
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CLINICAL_TRIALS trial_result · 2019-07-22Clinical Trial Update: The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy [Phase 4]
Phase 4 exploratory trial assessing ramelteon for insomnia in patients with major depressive disorder; results posted after completion.
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CLINICAL_TRIALS withdrawal · 2019-07-19Clinical Trial Update: Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD) [Phase 3]
Phase 3 study of rapastinel monotherapy for major depressive disorder has been withdrawn.
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Ketamine in the Treatment of Depression [Phase 2]
Phase 2 clinical trial update on ketamine for treating major depressive disorder; results completed and posted.
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: Goal Achievement After a Change to Vortioxetine in Adults With Major Depressive Disorder [Phase 4]
A Phase 4 trial update reports goal achievement after a change to vortioxetine in adults with major depressive disorder; results completed a…
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CLINICAL_TRIALS trial_result · 2019-07-10Clinical Trial Update: Effect of Bupropion on Seizure Threshold in Depressed Patients [Phase 4]
Phase 4 clinical trial investigating the effect of bupropion on seizure threshold in patients with major depressive disorder completed with …
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: A Study of LY2216684 and Theophylline in Healthy Subjects [Phase 1]
Phase 1 study evaluating LY2216684 with theophylline in healthy subjects; completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: A Study of L-DOPA for Depression and Slowing in Older Adults [Phase 4]
Phase 4 trial update on L-DOPA for depression and slowing in older adults, with completed status and posted results.
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CLINICAL_TRIALS trial_result · 2019-07-02Clinical Trial Update: Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDD [Phase 3]
Phase 3 trial comparing levomilnacipran ER to adjunctive quetiapine for adults with inadequate relief from SSRIs in major depressive disorde…
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CLINICAL_TRIALS trial_result · 2019-07-01Clinical Trial Update: Wellness Programs for Brain-Injured Individuals [NA]
Clinical trial evaluating wellness programs for brain-injured individuals has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-27Clinical Trial Update: Influenza Vaccine as a Novel Experimental Model of the Behavioral Immune Response in Depression [Phase 4]
Phase 4 clinical trial exploring influenza vaccine as a novel experimental model of the behavioral immune response in depression.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: A Phase 3 Study of Lu AA21004 in Patients With Major Depressive Disorder [Phase 3]
Phase 3 trial update for Lu AA21004 in major depressive disorder has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: A Study of LY2216684 in Healthy Participants [Phase 1]
Phase 1 study of LY2216684 in healthy participants completed; results posted.
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FDA approval · 2019-06-25FDA Approved: SPRAVATO — Supplemental Application (Janssen Pharmaceuticals Inc.)
FDA approved Janssen's supplemental application for SPRAVATO (esketamine hydrochloride), resulting in labeling changes for the product.
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-3 Study [Phase 3]
Phase 3 clinical trial update for ALKS 5461 in major depressive disorder; study completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Low Pulse Amplitude Focal ECT (LAP Study) [Phase 3]
Phase 3 clinical trial update for Low Pulse Amplitude Focal ECT (LAP Study) investigating depression; study completed.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Neurobehavioral Intervention as a Novel Treatment Approach for Emotion-Regulatory Deficits [NA]
A completed clinical trial from Stanford University evaluating a neurobehavioral intervention for emotion-regulatory deficits in anxiety and…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Combination Lexapro and Massage for Treatment of Depression in Older Adults [NA]
Clinical trial evaluating combination of Lexapro and massage for depression in older adults was terminated; results posted.