Low-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG) [Phase 2]
Phase 2 trial update evaluating vinblastine with or without bevacizumab in children with unresectable or progressive low grade glioma.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO) [Phase 3]
Phase 3 INDIGO study of vorasidenib (AG-881) in participants with residual or recurrent IDH-mutant low-grade glioma; results were posted in …
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas [Phase 2]
Phase 2 trial evaluating recombinant human endostatin in combination with CV regimen for pediatric low-grade gliomas has completed.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas [Phase 2]
Phase 2 clinical trial in recurrent pediatric low-grade gliomas assessing Poly-ICLC; completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-12-29Clinical Trial Update: Everolimus With and Without Temozolomide in Adult Low Grade Glioma [Phase 2]
Phase 2 trial investigating everolimus with and without temozolomide in adult low grade glioma has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-01Clinical Trial Update: Trial in Low Grade Glioma Patients: Wait or Treat [Phase 3]
A Phase 3 trial in low-grade glioma evaluating a wait-and-treat strategy was terminated.
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children [Phase 2]
Phase II study of everolimus in pediatric patients with recurrent or progressive low-grade gliomas has completed enrollment with results pos…
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CLINICAL_TRIALS trial_result · 2020-11-18Clinical Trial Update: Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma [Phase 2]
Phase II trial assessing oral vinorelbine in children with recurrent or progressive unresectable low-grade glioma has completed.
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery [Phase 2, Phase 3]
A clinical trial comparing radiotherapy alone versus radiotherapy plus temozolomide in high-risk low-grade gliomas after surgery is currentl…
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CLINICAL_TRIALS trial_result · 2019-05-20Clinical Trial Update: Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas [Phase 2]
Phase 2 clinical trial evaluating vinorelbine for children with progressive or recurrent low-grade gliomas has completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Temozolomide in Treating Patients With Low-Grade Glioma [Phase 2]
Phase 2 clinical trial update for temozolomide in patients with low-grade glioma. The study is completed and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
A clinical trial evaluating the PET tracer 11C-dLop as a marker of P-glycoprotein function in gliomas was terminated. The study enrolled pat…
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
A completed clinical trial evaluating rotating frame relaxation and diffusion-weighted imaging in patients with gliomas.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas [NA]
A completed clinical trial evaluating radiation therapy or combination chemotherapy for progressive low-grade gliomas in patients, as report…
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI
A completed clinical trial update assessing whether advanced pre- and intra-operative MRI improves surgical outcomes for patients with low-g…
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CLINICAL_TRIALS withdrawal · 2017-10-11Clinical Trial Update: Phase 2 Study of IDH305 in Low Grade Gliomas [Phase 2]
Phase 2 study of IDH305 for low-grade gliomas has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) [Phase 2]
A Phase 2 clinical trial update evaluating weekly vinblastine in chemotherapy-naive children with progressive low-grade glioma.
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CLINICAL_TRIALS research · 2017-03-28Clinical Trial Update: ROCOCO - Low Grade Glioma - Planning Study
ROCOCO is a completed planning study for low-grade glioma conducted by Maastricht Radiation Oncology. The trial entry indicates the study st…
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Late Effects of Proton Radiation Therapy in Patients With Low-Grade Glioma [NA]
This clinical trial update reports on the late effects of proton radiation therapy in patients with low-grade glioma; the study is completed…
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CLINICAL_TRIALS research · 2016-07-18Clinical Trial Update: Study of Tissue and Blood Samples From Patients With Low-Grade Glioma
This clinical trial update describes a completed study collecting tissue and blood samples from patients with low-grade glioma to study dise…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Angiogenic Profile and Non-invasive Imaging May Predict Tumor Progression of High Risk Group Low Grade Glioma (LGG)
The study suggests that angiogenic profiling and non-invasive imaging may help predict tumor progression in high-risk low-grade glioma.
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas [Phase 2]
Phase 2 trial of sorafenib in children and young adults with recurrent or progressive low-grade astrocytomas, including patients with neurof…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas [Phase 2]
Phase 2 trial evaluating everolimus (RAD001) in children with chemotherapy-refractory progressive or recurrent low-grade gliomas has complet…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: Confocal Laser Endomicroscopy for Brain Tumors [Phase 1]
A Phase 1 trial evaluating confocal laser endomicroscopy for brain tumors (low-grade glioma and high-grade glioma) has been terminated.
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CLINICAL_TRIALS research · 2015-09-22Clinical Trial Update: FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma
Update on a clinical trial evaluating FET-PET imaging for diagnosis and monitoring of low-grade gliomas, including astrocytoma, oligodendrog…