Low-grade Glioma
📧 Sign up to get email alerts when something new happens for Low-grade Glioma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. [Phase 2]
Phase 2 clinical trial evaluating trametinib in pediatric neuro-oncology patients with refractory tumors showing MAPK/ERK pathway activation…
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma [NA]
Clinical trial evaluating hippocampal-avoidance using proton therapy in various low-grade gliomas; the study is currently recruiting.
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared
A clinical trial update describing a study in low-grade gliomas evaluating patient-reported outcomes with vorasidenib in combination with ra…
-
CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During Surgery [NA]
A clinical trial is testing a new fluid to improve ultrasound image quality during brain tumor surgery and is currently recruiting. Sponsor:…
-
CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma [Phase 3]
A Phase 3 randomized trial comparing selumetinib to carboplatin and vincristine in patients with low-grade glioma is currently recruiting.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma [Phase 1, Phase 2]
Selumetinib is being studied in pediatric patients with recurrent or refractory low-grade glioma across Phase 1 and Phase 2 trials; the stud…
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) [Phase 1]
A Phase 1 PNOC021 trial of trametinib and everolimus for pediatric and young adult patients with recurrent gliomas has been suspended.
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma [Phase 3]
Phase 3 trial comparing selumetinib to carboplatin/vincristine in patients with neurofibromatosis type 1-associated low-grade glioma, with t…
-
CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations [Phase 2]
Phase 2 clinical trial update announcing the evaluation of FORE8394 in participants with cancers harboring BRAF alterations, including high-…
-
CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma [NA]
An ongoing clinical trial is evaluating the efficacy of Laser Interstitial Thermal Therapy in young patients with low-grade glioma, includin…
-
CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study of DS-1001b in Patients With Chemotherapy- and Radiotherapy-Naive IDH1 Mutated WHO Grade II Glioma [Phase 2]
DS-1001b is a Phase 2 study in IDH1-mutated, chemo- and radiotherapy-naive WHO Grade II glioma. The trial is currently active but not recrui…
-
CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas [Phase 1]
A Phase 1 clinical trial evaluating the combination of BGB-290 with temozolomide in patients with IDH1/IDH2-mutant gliomas, including gliobl…
-
CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma [NA]
A clinical trial of Vorasidenib guided by AGX PET in recurrent and low-grade glioma is not yet recruiting, with Huashan Hospital listed as s…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas [Phase 2]
A Phase 2 clinical trial evaluating the combination of dabrafenib and trametinib for BRAF V600-mutant low-grade gliomas is currently recruit…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) [Phase 3]
This clinical trial update describes a Phase 3 study (LOGGIC/FIREFLY-2) comparing DAY101 to standard-of-care chemotherapy for pediatric low-…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours [Phase 1]
A Phase 1 clinical trial in Japan is evaluating the safety and dosing of Tovorafenib in children and young adults with brain tumors, specifi…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Mind-Body Intervention in Glioma Couples [NA]
Clinical trial update for a mind-body intervention targeting glioma patients and their partners. The study is currently active but not recru…
-
CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of Avutometinib for People With Solid Tumor Cancers [Phase 1]
A Phase 1 study of Avutometinib for people with solid tumors, including CNS tumors and NF1-associated tumors, is currently recruiting.
-
CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of mirdametinib and vinblastine for newly diagnosed pediatric low-grade glioma with…
-
CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial [Phase 2]
A Phase 2 trial (PODS) is evaluating post-operative dosing of dexamethasone in brain tumor patients after craniotomy; the study is currently…
-
CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Niraparib In Recurrent IDH 1/2 Gliomas [EARLY_Phase 1]
An early-phase 1 trial update evaluating niraparib in recurrent IDH1/2-mutant gliomas, including low-grade and malignant gliomas.
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma [Phase 1, Phase 2]
Clinical trial update for SJ901 evaluating mirdametinib in children, adolescents, and young adults with low-grade glioma; the Phase 1/Phase …
-
CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration [Phase 1, Phase 2]
Status update for a Phase 1/2 trial evaluating dabrafenib, trametinib, and hydroxychloroquine in patients with recurrent low-grade or high-g…
-
CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma [NA]
Ongoing clinical trial evaluating intensity-modulated stereotactic radiotherapy for patients with grade II–IV gliomas, including glioblastom…
-
CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors
The study aims to establish a living tissue bank of patient-derived glioma organoids. Recruitment is ongoing for patients with low-grade gli…