Low-grade Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Seizure Control as a New Metric in Assessing Efficacy of Tumor Treatment in Patients With Low Grade Glioma
This clinical trial update discusses using seizure control as a new metric to assess the efficacy of tumor treatment in patients with low-gr…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: FCI in Post-operative Low Grade Gliomas [NA]
A clinical trial evaluating FCI in patients with post-operative low-grade gliomas has completed.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma [Phase 3]
This clinical trial update describes a Phase 3 study comparing selumetinib alone to selumetinib plus vinblastine in patients with recurrent …
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma [EARLY_Phase 1]
This update reports the completion of an early-phase study of AB-218 in IDH1-mutated low-grade glioma, with the trial status now listed as C…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms [Phase 2]
A Phase 2 clinical trial evaluating Fluoroethyltyrosine for the evaluation of intracranial neoplasms, including low-grade glioma and recurre…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: DAY101 In Gliomas and Other Tumors [Phase 1]
A Phase 1 trial update for DAY101 in gliomas and other tumors, with the Low-grade glioma arm reported as completed.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation [Phase 3]
A Phase 3 trial evaluating vorasidenib for Asian participants with residual or recurrent grade 2 IDH-mutant glioma is currently active but n…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Fluorescence Spectroscopy Guided Surgery [Phase 1]
Phase 1 clinical trial evaluating fluorescence spectroscopy guided surgery for patients with gliomas. The study including low-grade glioma a…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype [Phase 2]
A Phase 2 trial of nivolumab in IDH-mutant gliomas, with and without hypermutator phenotype, has results posted on ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Study of MEK162 for Children With Low-Grade Gliomas [Phase 1, Phase 2]
Phase 1/2 trial of MEK162 for children with low-grade gliomas has completed, with results posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas [Phase 1]
Phase 1 clinical trial update for Vorasidenib in combination with a tumor-specific peptide vaccine in recurrent IDH1-mutant lower-grade glio…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue [NA]
SonoClear is reporting completion of its clinical trial evaluating Acoustic Coupling Fluid (ACF) for brain-tissue–mimicking use in condition…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration [Phase 3]
This Phase 3 trial compares FCN-159 monotherapy with investigator's-choice chemotherapy for pediatric low-grade glioma with BRAF alterations…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation [Phase 2]
Phase 2 clinical trial evaluating proton radiotherapy for pediatric brain tumors requiring partial brain irradiation has completed enrollmen…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Phase II Trial of Poly-ICLC for Low-Grade Gliomas [Phase 2]
A terminated Phase II trial evaluating poly-ICLC for low-grade gliomas in NF1 patients has posted results.
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Feasibility of the LUM Imaging System for Detection of Cancer to the Brain [NA]
A feasibility trial of the LUM Imaging System for detecting cancer in the brain has been terminated.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of BGB-290 in combination with temozolomide in patients with recurrent gli…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas [Phase 1]
This Phase 1 pilot trial evaluated glioma-associated antigen vaccines with the Toll-like receptor 3 agonist Poly-ICLC in pediatric gliomas a…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluating observation or radiation therapy with or without combination chemotherapy for low-grade glioma.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Evaluation of the Correlation Between Molecular Phenotype and Radiological Signature (by PET-scanner and MRI) of Incident WHO II and III Grade Gliomas.
A completed study evaluating the relationship between molecular phenotype and radiological features on PET and MRI in patients with incident…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) [Phase 1]
Phase 1 trial evaluating varlilumab in combination with the IMA950 vaccine and Poly-ICLC in adults with WHO grade II low-grade glioma; the s…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG) [Phase 2]
Phase 2 trial update evaluating vinblastine with or without bevacizumab in children with unresectable or progressive low grade glioma.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO) [Phase 3]
Phase 3 INDIGO study of vorasidenib (AG-881) in participants with residual or recurrent IDH-mutant low-grade glioma; results were posted in …
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas [Phase 2]
Phase 2 trial evaluating recombinant human endostatin in combination with CV regimen for pediatric low-grade gliomas has completed.