Ischemia-reperfusion Injury
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CLINICAL_TRIALS trial_result · 2021-05-28Clinical Trial Update: Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation [NA]
A terminated clinical trial investigated the effect of nitric oxide on ischemia/reperfusion injury during extended donor criteria liver tran…
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery [Phase 1, Phase 2]
Phase 1/2 trial evaluating intravenous Bendavia for reperfusion injury during renal artery angioplasty; the study was terminated with result…
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Reparixin in Prevention of Delayed Graft Function After Kidney Transplantation [Phase 2]
Phase 2 clinical trial update on reparixin to prevent delayed graft function after kidney transplantation following ischemia-reperfusion inj…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass [NA]
This completed clinical trial evaluated whether administering inhaled nitric oxide during neonatal cardiopulmonary bypass reduces ischemia/r…
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy [NA]
Clinical trial update on remote ischemic preconditioning in living donor hepatectomy; study completed and results posted.
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Clinical Study of Cardiomyopeptidin on Postoperative Ischemia-reperfusion Injury in Patients With Primary PCI [Phase 4]
Phase 4 clinical trial update for Cardiomyopeptidin in patients undergoing primary PCI, focusing on myocardial survival area and left ventri…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Desflurane Preconditioning in Hepatectomies [NA]
A completed clinical trial update examining desflurane preconditioning in liver resection to mitigate ischemia-reperfusion injury.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement [NA]
Completed clinical trial comparing Del Nido versus cold blood cardioplegia in aortic valve replacement; the study status indicates completio…
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CLINICAL_TRIALS trial_result · 2018-11-19Clinical Trial Update: The Effect of Pregabalin Given Preoperatively on the Tourniquet Induced Ischemia-reperfusion [Phase 4]
Phase 4 clinical trial evaluating the effect of pregabalin given preoperatively on tourniquet-induced ischemia-reperfusion injury has comple…
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CLINICAL_TRIALS trial_result · 2018-06-25Clinical Trial Update: C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI [Phase 1, Phase 2]
Phase 1/2 trial evaluating C1 esterase inhibitor given before and after kidney transplant to prevent Delayed graft function and ischemia-rep…
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: Effect of Dexmedetomidine on Ischemia-Reperfusion Injury in Lower Extremity Operations [NA]
A completed clinical trial evaluating the effect of dexmedetomidine on ischemia-reperfusion injury in patients undergoing lower-extremity ar…
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Dexmedetomidine Effect on Mitochondrial Function [Phase 4]
Phase 4 clinical trial evaluating the effect of dexmedetomidine on mitochondrial function, sponsored by The Hospital for Sick Children; the …
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Microcirculation and Anesthesia in Vascular Surgery
Completed clinical trial evaluating microcirculation and anesthesia in vascular surgery, with focus on ischemia-reperfusion injury and aorti…
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CLINICAL_TRIALS trial_result · 2017-12-15Clinical Trial Update: Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting [Phase 2]
Phase 2 trial updating the protection of the heart with doxycycline during coronary artery bypass grafting.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers [Phase 3]
Phase 3 trial update evaluating the role of oxygen in suspected acute myocardial infarction using biomarkers; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers [Phase 1]
Phase 1 pilot study in healthy volunteers assessing how oxygen treatment influences mechanisms involved in ischemia-reperfusion injury.
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome. [Phase 2]
Phase 2 clinical trial update evaluating remote ischemic conditioning to attenuate myocardial injury and improve operative outcomes during c…
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery [NA]
Clinical trial evaluating erythropoietin for myocardial ischemia-reperfusion injury during coronary artery bypass grafting has completed.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Ischemia Reperfusion: Prostaglandins and Antioxidants [NA]
A University of Essex-sponsored trial investigating prostaglandins and antioxidants for ischemia-reperfusion injury has completed.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Limitation of Ischemic Injury of a Kidney Stored in Machine Perfusion in Hypothermia - Evaluation of the Impact on Kidney Allograft Function [Phase 2]
Phase 2 trial evaluating whether hypothermic machine perfusion can limit ischemic injury to a transplanted kidney and improve allograft func…
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CLINICAL_TRIALS research · 2017-03-28Clinical Trial Update: Omega 3 Lipid Emulsions and Liver Transplantation [NA]
A clinical trial from Mansoura University is evaluating omega-3 lipid emulsions for ischemia-reperfusion injury in liver transplantation, bu…
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: TOP-Study (Tacrolimus Organ Perfusion): Treatment of Ischemia Reperfusion Injury in Marginal Organs With an ex Vivo Tacrolimus Perfusion [Phase 2, Phase 3]
The TOP-Study evaluated ex vivo tacrolimus perfusion to treat ischemia-reperfusion injury in marginal liver grafts (Phase 2/3). The trial st…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus [NA]
A completed clinical trial evaluated tacrolimus flushing for use during liver transplantation to mitigate ischemia-reperfusion injury and ea…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Effects of Dexmedetomidine on the Liver Injury After Hepatectomy [Phase 4]
Phase 4 trial evaluating whether dexmedetomidine reduces liver injury after hepatectomy in the context of ischemia-reperfusion, with the stu…
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: The Effect of Melatonin on Ischemia-reperfusion Injury Following Acute Myocardial Infarction [Phase 2]
Phase 2 trial examining whether melatonin can reduce ischemia-reperfusion injury after acute myocardial infarction has completed.