Ischemia-reperfusion Injury
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and potential efficacy of treprostinil (Remodulin) to reduce ischemia-reperfusion injury…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Intravenous Estrogen in Kidney Transplant Study [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 clinical trial evaluating intravenous estrogen to mitigate ischemia-reperfusion injury in ki…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of BX-001N in Preventing Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) and Major Adverse Kidney Events (MAKE) [Phase 2]
A Phase 2 clinical trial evaluating BX-001N for preventing cardiac surgery-associated acute kidney injury and major adverse kidney events is…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI [Phase 2]
Phase 2 clinical trial evaluating whether L-Carnitine affects biomarkers of myocardial reperfusion injury in patients with ST-elevation myoc…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Auricular Vagus Stimulation and STEMI [NA]
A clinical trial evaluating auricular vagus nerve stimulation for patients with STEMI/acute coronary syndrome is currently recruiting at the…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Differential Impact of Pringle and Portal Vein Occlusion on Myocardial Injury After Non-Cardiac Surgeries.
A clinical trial evaluating how Pringle vs. portal vein occlusion affects myocardial injury risk during non-cardiac surgery; currently recru…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: OSA as a Remote Ischemic Preconditioning in Vascular Surgery
A ClinicalTrials.gov update reports a study evaluating obstructive sleep apnea as a remote ischemic preconditioning approach in vascular sur…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY) [Phase 2]
Phase 2 CINERGY trial evaluating whether administering a calcineurin inhibitor to neurologically deceased donors can reduce delayed graft fu…
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Safety and Efficacy of Remote Ischemic Conditioning for Patients Taking Off-pump Coronary Artery Bypass Grafting [NA]
A clinical trial is investigating remote ischemic conditioning for patients undergoing off-pump coronary artery bypass grafting. The study i…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys [Phase 3]
This update describes a Phase 3 trial comparing intermittent versus continuous surface oxygen during hypothermic machine perfusion of donati…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome. [Phase 2]
Phase 2 clinical trial update evaluating remote ischemic conditioning to attenuate myocardial injury and improve operative outcomes during c…
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CLINICAL_TRIALS research · 2017-10-24Clinical Trial Update: Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery [NA]
Clinical trial evaluating erythropoietin for myocardial ischemia-reperfusion injury during coronary artery bypass grafting has completed.
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CLINICAL_TRIALS research · 2017-03-28Clinical Trial Update: Omega 3 Lipid Emulsions and Liver Transplantation [NA]
A clinical trial from Mansoura University is evaluating omega-3 lipid emulsions for ischemia-reperfusion injury in liver transplantation, bu…
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CLINICAL_TRIALS research · 2015-04-30Clinical Trial Update: Mitochondrial Apoptotic Pathway Induced by Myocardial Ischemia-Reperfusion Injury in Human [NA]
A clinical trial update investigating the mitochondrial apoptotic pathway in human myocardial ischemia-reperfusion injury, sponsored by Wang…
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CLINICAL_TRIALS research · 2013-04-17Clinical Trial Update: Study of the Glycocalyx in Abdominal Aortic Aneurysm [NA]
A clinical trial update on a study of the glycocalyx in abdominal aortic aneurysm, with the current status listed as UNKNOWN.
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CLINICAL_TRIALS research · 2013-01-18Clinical Trial Update: Ischaemia-réperfusion During the Coronary Surgery With Beating Heart [Phase 3]
Phase 3 clinical trial update on ischemia-reperfusion during beating-heart coronary surgery; current status is unknown.
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CLINICAL_TRIALS research · 2012-08-14Clinical Trial Update: Effect of Remote Ischemic Perconditioning on Acute Kidney Injury in Adult Valve Replace [NA]
An update on a clinical trial evaluating whether remote ischemic perconditioning can reduce acute kidney injury in adults undergoing valve r…
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CLINICAL_TRIALS research · 2011-05-06Clinical Trial Update: Intermittent Normoxia Reduces Myocardial Reperfusion Injury [NA]
A clinical trial update from Central South University investigates whether intermittent normoxia can reduce myocardial reperfusion injury, w…
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CLINICAL_TRIALS research · 2010-11-11Clinical Trial Update: Thymoglobulin Induction in Kidney Transplant Recipients [Phase 3]
A Phase 3 clinical trial evaluating thymoglobulin induction in kidney transplant recipients; current status is not disclosed.
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CLINICAL_TRIALS research · 2010-03-12Clinical Trial Update: Infusion of a Single Dose of Erythropoietin to Prevent Injury in an Ischemia Reperfusion Forearm Model [NA]
A clinical trial update describing the use of a single dose of erythropoietin to prevent ischemia-reperfusion injury in a forearm model; the…
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CLINICAL_TRIALS research · 2008-07-18Clinical Trial Update: Effects of Sevoflurane in Subanesthetic Concentrations on the Forearm Perfusion [Phase 4]
Clinical trial update on the effects of subanesthetic sevoflurane on forearm perfusion in ischemia/reperfusion injury (Phase 4); status is U…